Non-Alcoholic Cirrhosis and Heart Rate Variability: A Systematic Mini-Review

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Imagem de Miniatura
Citações na Scopus
5
Tipo de produção
article
Data de publicação
2020
Título da Revista
ISSN da Revista
Título do Volume
Editora
MDPI
Autores
ARAB, Claudia
ABREU, Luiz Carlos
VALENTI, Vitor E.
MONTEIRO, Carlos B. M.
Citação
MEDICINA-LITHUANIA, v.56, n.3, article ID 116, 11p, 2020
Projetos de Pesquisa
Unidades Organizacionais
Fascículo
Resumo
Background and Objectives: Cirrhosis is a liver disease that causes about one million deaths annually worldwide. The estimated cirrhosis prevalence ranges from 4.5-9.5% in the general population. Up to 40% of cirrhotic patients are asymptomatic and may be diagnosed late. Studies have described the importance of the functions of the liver and autonomic nervous system (ANS) and their relationship. There is limited information available on non-alcoholic cirrhosis and heart rate variability (HRV), which is a measure of the ANS. This study aimed to evaluate cardiac autonomic modulation through HRV in non-alcoholic cirrhosis individuals reported in previous observational and clinical trial studies. Materials and Methods: We performed a systematic review according to the Preferred Reporting Items for Systematic Review and Meta-Analyses (PRISMA) statement using the Medline, Scopus, and Web of Science electronic databases. Five studies were identified and reviewed. Results: HRV was decreased in patients with non-alcoholic cirrhosis, even in the first stage. Conclusions: HRV could be used as a complementary method to improve both the diagnosis and prognosis of non-alcoholic cirrhosis.
Palavras-chave
liver cirrhosis, autonomic nervous system disorders, end stage liver disease, heart rate variability
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