Hypertension and arterial stiffness in heart transplantation patients

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dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP
dc.contributor.authorSOUZA-NETO, Joao David de
dc.contributor.authorOLIVEIRA, Italo Martins de
dc.contributor.authorLIMA-ROCHA, Hermano Alexandre
dc.contributor.authorOLIVEIRA-LIMA, Jose Wellington
dc.contributor.authorBACAL, Fernando
dc.date.accessioned2016-12-20T16:44:27Z
dc.date.available2016-12-20T16:44:27Z
dc.date.issued2016
dc.description.abstractOBJECTIVES: Post-transplantation hypertension is prevalent and is associated with increased cardiovascular morbidity and subsequent graft dysfunction. The present study aimed to identify the factors associated with arterial stiffness as measured by the ambulatory arterial stiffness index. METHODS: The current study used a prospective, observational, analytical design to evaluate a group of adult heart transplantation patients. Arterial stiffness was obtained by monitoring ambulatory blood pressure and using the ambulatory arterial stiffness index as the surrogate outcome. Multivariate logistic regression analyses were performed to control confounding. RESULTS: In a group of 85 adult heart transplantation patients, hypertension was independently associated with arterial stiffness (OR 4.98, CI 95% 1.06-23.4) as well as systolic and diastolic blood pressure averages and nighttime descent. CONCLUSIONS: Measurement of ambulatory arterial stiffness index is a new, non-invasive method that is easy to perform, may contribute to better defining arterial stiffness prognosis and is associated with hypertension.
dc.description.indexMEDLINE
dc.description.sponsorshipFundacao Cearense de Apoio do Desenvolvimento Cientifico e Tecnologico (FUNCAP) [MD1-0053-00037.01.00/12]
dc.identifier.citationCLINICS, v.71, n.9, p.494-499, 2016
dc.identifier.doi10.6061/clinics/2016(09)02
dc.identifier.eissn1980-5322
dc.identifier.issn1807-5932
dc.identifier.urihttps://observatorio.fm.usp.br/handle/OPI/17279
dc.language.isoeng
dc.publisherHOSPITAL CLINICAS, UNIV SAO PAULO
dc.relation.ispartofClinics
dc.rightsopenAccess
dc.rights.holderCopyright HOSPITAL CLINICAS, UNIV SAO PAULO
dc.subjectVascular Stiffness
dc.subjectHypertension
dc.subjectGraft Rejection
dc.subjectBlood Pressure Monitoring Ambulatory
dc.subject.otherblood-pressure
dc.subject.otherpulse pressure
dc.subject.otheraortic stiffness
dc.subject.othercardiac transplantation
dc.subject.othercardiovascular events
dc.subject.otherinternational society
dc.subject.otheraugmentation index
dc.subject.otherdiabetes-mellitus
dc.subject.otherrenal-function
dc.subject.otherrecipients
dc.subject.wosMedicine, General & Internal
dc.titleHypertension and arterial stiffness in heart transplantation patients
dc.typearticle
dc.type.categoryoriginal article
dc.type.versionpublishedVersion
dspace.entity.typePublication
hcfmusp.author.externalSOUZA-NETO, Joao David de:Hosp Messejana Dr Carlos Alberto Studart Gomes, Unidade Transplante & Insuficiencia Cardiaca, Fortaleza, CE, Brazil
hcfmusp.author.externalOLIVEIRA, Italo Martins de:Hosp Messejana Dr Carlos Alberto Studart Gomes, Unidade Transplante & Insuficiencia Cardiaca, Fortaleza, CE, Brazil
hcfmusp.author.externalLIMA-ROCHA, Hermano Alexandre:Univ Fed Ceara, Dept Saude Comunitaria, Fortaleza, CE, Brazil
hcfmusp.author.externalOLIVEIRA-LIMA, Jose Wellington:Univ Estadual Ceara, Dept Saude Comunitaria, Fortaleza, CE, Brazil
hcfmusp.citation.scopus9
hcfmusp.contributor.author-fmusphcFERNANDO BACAL
hcfmusp.description.beginpage494
hcfmusp.description.endpage499
hcfmusp.description.issue9
hcfmusp.description.volume71
hcfmusp.origemWOS
hcfmusp.origem.pubmed27652829
hcfmusp.origem.scieloSCIELO:S1807-59322016000900494
hcfmusp.origem.scopus2-s2.0-84988027370
hcfmusp.origem.wosWOS:000382872800002
hcfmusp.publisher.citySAO PAULO
hcfmusp.publisher.countryBRAZIL
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