Executive function and depressive symptoms of retardation in nonelderly stroke patients

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dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP
dc.contributor.authorSOBREIRO, Matildes F. M.
dc.contributor.authorMIOTTO, Eliane Correa
dc.contributor.authorTERRONI, Luisa
dc.contributor.authorTINONE, Gisela
dc.contributor.authorIOSIFESCU, Dan V.
dc.contributor.authorLUCIA, Mara C. S. de
dc.contributor.authorSCAFF, Milberto
dc.contributor.authorLEITE, Claudia da Costa
dc.contributor.authorAMARO JR., Edson
dc.contributor.authorFRAGUAS, Renerio
dc.date.accessioned2014-09-30T14:42:28Z
dc.date.available2014-09-30T14:42:28Z
dc.date.issued2014
dc.description.abstractThe depression-executive dysfunction syndrome, a late-onset depression of vascular origin with executive dysfunction and psychomotor retardation, has also been described after stroke. We verified whether this syndrome also occurs in nonelderly stroke patients by investigating the association between domains of depressive symptoms with executive functions in 87 first-ever ischemic stroke patients. The retardation domain of the 31-item Hamilton Rating Scale for Depression was associated with decreased performance on verbal fluency (assessed with FAS). The association was maintained for younger patients (aged <60 years) after adjusting for confounders. This result supports the clinical presentation of depression-executive dysfunction syndrome in younger stroke patients. Confirmation of this finding, its neural correlates, and clinical implication deserve further investigation.
dc.description.indexMEDLINE
dc.description.sponsorshipIcahn School of Medicine at Mount Sinai from National Institute of Mental Health - NIMH (NIH)
dc.description.sponsorshipAstraZeneca
dc.description.sponsorshipBrainsway
dc.description.sponsorshipEuthymics
dc.description.sponsorshipNeosync
dc.description.sponsorshipRoche
dc.description.sponsorshipAvanir
dc.description.sponsorshipCNS Response
dc.description.sponsorshipOtsuka
dc.description.sponsorshipLundbeck
dc.description.sponsorshipServier
dc.description.sponsorshipSunovion
dc.identifier.citationJOURNAL OF CLINICAL AND EXPERIMENTAL NEUROPSYCHOLOGY, v.36, n.6, p.636-647, 2014
dc.identifier.doi10.1080/13803395.2014.925092
dc.identifier.eissn1744-411X
dc.identifier.issn1380-3395
dc.identifier.urihttps://observatorio.fm.usp.br/handle/OPI/7550
dc.language.isoeng
dc.publisherTAYLOR & FRANCIS INC
dc.relation.ispartofJournal of Clinical and Experimental Neuropsychology
dc.rightsrestrictedAccess
dc.rights.holderCopyright TAYLOR & FRANCIS INC
dc.subjectExecutive functions
dc.subjectDepressive symptoms
dc.subjectStroke
dc.subjectNeuropsychological tests
dc.subjectVascular depression
dc.subject.otherlate-life depression
dc.subject.othervascular cognitive impairment
dc.subject.otherwhite-matter hyperintensities
dc.subject.otherhuman cerebral-cortex
dc.subject.otherpoststroke depression
dc.subject.otherdysfunction syndrome
dc.subject.otherfollow-up
dc.subject.otherneuropsychological deficits
dc.subject.otherantidepressant-treatment
dc.subject.otherclinical determinants
dc.subject.wosPsychology, Clinical
dc.subject.wosClinical Neurology
dc.subject.wosPsychology
dc.titleExecutive function and depressive symptoms of retardation in nonelderly stroke patients
dc.typearticle
dc.type.categoryoriginal article
dc.type.versionpublishedVersion
dspace.entity.typePublication
hcfmusp.affiliation.countryEstados Unidos
hcfmusp.affiliation.countryisous
hcfmusp.author.externalIOSIFESCU, Dan V.:Icahn Sch Med Mt Sinai, Mood & Anxiety Disorders Program, New York, NY 10029 USA
hcfmusp.citation.scopus5
hcfmusp.contributor.author-fmusphcMATILDES DE FREITAS MENEZES SOBREIRO
hcfmusp.contributor.author-fmusphcELIANE CORREA MIOTTO
hcfmusp.contributor.author-fmusphcLUISA DE MARILLAC NIRO TERRONI
hcfmusp.contributor.author-fmusphcGISELA TINONE
hcfmusp.contributor.author-fmusphcMARA CRISTINA SOUZA DE LUCIA
hcfmusp.contributor.author-fmusphcMILBERTO SCAFF
hcfmusp.contributor.author-fmusphcCLAUDIA DA COSTA LEITE
hcfmusp.contributor.author-fmusphcEDSON AMARO JUNIOR
hcfmusp.contributor.author-fmusphcRENERIO FRAGUAS JUNIOR
hcfmusp.description.beginpage636
hcfmusp.description.endpage647
hcfmusp.description.issue6
hcfmusp.description.volume36
hcfmusp.origemWOS
hcfmusp.origem.pubmed24974834
hcfmusp.origem.scopus2-s2.0-84903695292
hcfmusp.origem.wosWOS:000338987200008
hcfmusp.publisher.cityPHILADELPHIA
hcfmusp.publisher.countryUSA
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hcfmusp.remissive.sponsorshipLundbeck
hcfmusp.remissive.sponsorshipNIH
hcfmusp.remissive.sponsorshipOtsuka
hcfmusp.remissive.sponsorshipRoche
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