Multivisceral resection vs standard gastrectomy for gastric adenocarcinoma

Imagem de Miniatura
Arquivos
art_DIAS_Multivisceral_resection_vs_standard_gastrectomy_for_gastric_adenocarcinoma_2020.PDF (1.1 MB)
Citações na Scopus
9
Tipo de produção
article
Data de publicação
2020
DOI
Scopus
Web of Science
PubMed
Título da Revista
ISSN da Revista
Título do Volume
Editora
WILEY
Autores
Citação
JOURNAL OF SURGICAL ONCOLOGY, v.121, n.5, p.840-847, 2020
Projetos de Pesquisa
Unidades Organizacionais
Fascículo
Resumo
Introduction Multivisceral resection (MVR) is potentially curative for selected gastric cancer patients, supposedly at the cost of increased complications. However, current data comparing MVR to standard gastrectomy (SG) is lacking. Objectives Compare complications and survival after MVR and SG. Methods In a retrospective cohort of 1015 patients with gastric adenocarcinoma, 58 underwent MVR and 466 SG. Groups were compared concerning their characteristics, complications, and survival. Results One hundred seventy-six patients had postoperative complications. Major complications were more frequent after MVR (P = .002). Surgical mortality was 8.6% and 4.9% for MVR and SG (P = .221). Older age, higher morbidities, and MVR were independent risk factors for major complications. The odds ratio for major complications was 5.89 for MVR with one or two organs and 38.01 for MVR with three or more organs. The pancreas was the most commonly removed organ and pT4b disease were confirmed in 34 (58.6%) of the MVR cases. Disease-free survival (DFS) was lower in MVR patients (51% vs 77.8%; P < .001), being worse according to the number of organs resected. In pN+ patients, DFS was worse after MVR. DFS was equivalent to pT4b and non-pT4b in the MVR group. Conclusions Increased morbidity and lower survival are expected for gastric cancer patients undergoing MVR.
Palavras-chave
gastric adenocarcinoma, gastric cancer, multiorgan, multivisceral resection
URI
https://observatorio.fm.usp.br/handle/OPI/35946
Referências
  1. Amin MB, 2017, CA-CANCER J CLIN, V67, P93, DOI 10.3322/caac.21388
  2. Brar SS, 2012, GASTRIC CANCER, V15, pS100, DOI 10.1007/s10120-011-0074-9
  3. Carboni F, 2005, J SURG ONCOL, V90, P95, DOI 10.1002/jso.20244
  4. CHARLSON ME, 1987, J CHRON DIS, V40, P373, DOI 10.1016/0021-9681(87)90171-8
  5. Cheng CT, 2011, ANN SURG ONCOL, V18, P1606, DOI 10.1245/s10434-010-1534-x
  6. D'Amato A, 2004, HEPATO-GASTROENTEROL, V51, P609
  7. Dhar DK, 2001, J SURG ONCOL, V76, P278, DOI 10.1002/jso.1046
  8. Dias AR, 2016, GASTRIC CANCER, V19, P136, DOI 10.1007/s10120-014-0443-2
  9. Dindo D, 2004, ANN SURG, V240, P205, DOI 10.1097/01.sla.0000133083.54934.ae
  10. Doyle DJ, 2017, AM SOC ANESTHESIOLOG
  11. Isozaki Hiroshi, 2000, Gastric Cancer, V3, P202, DOI 10.1007/PL00011718
  12. Japanese Gastric Canc Assoc, 2017, GASTRIC CANCER, V20, P1, DOI 10.1007/s10120-016-0622-4
  13. Jeong O, 2009, J SURG ONCOL, V100, P115, DOI 10.1002/jso.21306
  14. Kim DY, 2006, ANZ J SURG, V76, P453, DOI 10.1111/j.1445-2197.2006.03751.x
  15. Kobayashi A, 2004, J GASTROINTEST SURG, V8, P464, DOI 10.1016/j.gassur.2003.12.018
  16. Ramos MFKP, 2019, ABCD-ARQ BRAS CIR DI, V32, DOI 10.1590/0102-672020190001e1435
  17. Kunisaki C, 2006, J AM COLL SURGEONS, V202, P223, DOI 10.1016/j.jamcollsurg.2005.10.020
  18. Li MZ, 2014, PLOS ONE, V9, DOI 10.1371/journal.pone.0107061
  19. Martin RCG, 2002, ANN SURG, V236, P159, DOI 10.1097/00000658-200208000-00003
  20. Mendonca EQ, 2018, CLINICS, V73, DOI 10.6061/clinics/2018/e553s
  21. Mita K, 2017, J GASTROINTEST SURG, V21, P1993, DOI 10.1007/s11605-017-3559-y
  22. Mita K, 2012, AM J SURG, V203, P107, DOI 10.1016/j.amjsurg.2010.12.007
  23. Onate-Ocana LF, 2008, J SURG ONCOL, V98, P336, DOI 10.1002/jso.21118
  24. Ozer I, 2009, AM J SURG, V198, P25, DOI 10.1016/j.amjsurg.2008.06.031
  25. Pacelli F, 2013, JAMA SURG, V148, P353, DOI 10.1001/2013.jamasurg.309
  26. Pereira MA, 2015, HISTOPATHOLOGY, V66, P388, DOI 10.1111/his.12532
  27. Pereira MA, 2018, J GASTROINTEST SURG, V22, P23, DOI 10.1007/s11605-017-3517-8
  28. Persiani R, 2008, J AM COLL SURGEONS, V207, P13, DOI 10.1016/j.jamcollsurg.2007.12.050
  29. Ramos MFKP, 2020, J GASTROINTEST SURG, V24, P19, DOI 10.1007/s11605-019-04462-z
  30. Saito H, 2001, Gastric Cancer, V4, P206, DOI 10.1007/s10120-001-8011-y
  31. Szor DJ, 2018, CLINICS, V73, DOI 10.6061/clinics/2018/e360
  32. Szor DJ, 2018, J SURG ONCOL, V117, P851, DOI 10.1002/jso.25036
  33. Tran TB, 2015, ANN SURG ONCOL, V22, pS840, DOI 10.1245/s10434-015-4694-x

Coleções
Artigos e Materiais de Revistas Científicas - FM/MGT
Artigos e Materiais de Revistas Científicas - HC/ICESP
Artigos e Materiais de Revistas Científicas - HC/ICHC
Artigos e Materiais de Revistas Científicas - LIM/24
Artigos e Materiais de Revistas Científicas - LIM/35
Artigos e Materiais de Revistas Científicas - ODS/03