Semen Analysis and Fertility Rates after Bariatric Surgery in Males

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dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP
dc.contributor.authorROSENBLATT, Alberto
dc.contributor.authorFAINTUCH, Joel
dc.contributor.authorPAJECKI, Denis
dc.contributor.authorSANTO, Marco Aurelio
dc.contributor.authorFAINTUCH, Salomao
dc.contributor.authorCECCONELLO, Ivan
dc.date.accessioned2017-10-24T13:18:00Z
dc.date.available2017-10-24T13:18:00Z
dc.date.issued2017
dc.description.abstractBackground: Obesity poses challenges to male reproduction, but the effect of bariatric surgery on semen parameters and fertility is debated. This study evaluates Roux-en-Y gastric bypass (RYGB) influence on these variables. Methods: Seventy-nine sexually active men attempting to conceive with a partner were stratified into four groups: Group 1 (n = 23)-bariatric follow-up >= 5 years; Group 2 (n = 23)-mean bariatric follow-up 2 years; Group 3-obese controls (n = 18); Group 4-lean controls (n = 15). Groups 2, 3, and 4 were matched for age; Groups 1, 2, and 3 were matched for body mass index (BMI). Sexual quality of life questionnaire for males (SQOL-M), fasting blood glucose, C-reactive protein, vitamin D, zinc, total testosterone (TT), and free testosterone (FT), estradiol (E2), sex hormone-binding globulin (SHBG), and semen parameters were investigated. Results: SQOL-M scores increased; vitamin D was low in most of Group 2 and Group 3 participants, negatively correlating with BMI (p < 0.01). TT, FT, and SHBG improved postoperatively; however, E2 remained elevated. Semen aberrations occurred in 57.1% of Group 2 patients and BMI correlated with oligoasthenoteratospermia. Scant bariatric men fathered a child (13.0% preoperatively, 4.3% postoperatively, not significant). Conclusion: Semen abnormalities and subfertility were observed after RYGB, despite improved androgenic profile and SQOL-M. Possible negative impacts of hyperestrogenism and hypovitaminosis D on semen parameters warrant further studies.
dc.description.indexPubMed
dc.description.sponsorshipCAPES, Brazil [PNPD20131663-USP/ 3300201022P2]
dc.identifier.citationBARIATRIC SURGICAL PRACTICE AND PATIENT CARE, v.12, n.3, p.94-99, 2017
dc.identifier.doi10.1089/bari.2017.0016
dc.identifier.eissn2168-0248
dc.identifier.issn2168-023X
dc.identifier.urihttps://observatorio.fm.usp.br/handle/OPI/21906
dc.language.isoeng
dc.publisherMARY ANN LIEBERT, INC
dc.relation.ispartofBariatric Surgical Practice and Patient Care
dc.rightsrestrictedAccess
dc.rights.holderCopyright MARY ANN LIEBERT, INC
dc.subjectbariatric surgery
dc.subjectsemen analysis
dc.subjectmale fertility
dc.subjectsex hormones
dc.subjectandrogens
dc.subjectvitamins
dc.subjecttrace elements
dc.subjectmale obesity
dc.subject.othery gastric bypass
dc.subject.otherbody-mass index
dc.subject.othervitamin-d
dc.subject.otherhuman osteoblasts
dc.subject.othersperm parameters
dc.subject.otherlong-term
dc.subject.otherdeficiencies
dc.subject.othermetaanalysis
dc.subject.otherassociation
dc.subject.otherinfertility
dc.subject.wosNursing
dc.titleSemen Analysis and Fertility Rates after Bariatric Surgery in Males
dc.typearticle
dc.type.categoryoriginal article
dc.type.versionpublishedVersion
dspace.entity.typePublication
hcfmusp.affiliation.countryEstados Unidos
hcfmusp.affiliation.countryisous
hcfmusp.author.externalFAINTUCH, Salomao:Harvard Med Sch, New England Deaconess Med Ctr, Dept Radiol, Boston, MA USA
hcfmusp.citation.scopus0
hcfmusp.contributor.author-fmusphcALBERTO ROSENBLATT
hcfmusp.contributor.author-fmusphcJOEL FAINTUCH
hcfmusp.contributor.author-fmusphcDENIS PAJECKI
hcfmusp.contributor.author-fmusphcMARCO AURELIO SANTO
hcfmusp.contributor.author-fmusphcIVAN CECCONELLO
hcfmusp.description.beginpage94
hcfmusp.description.endpage99
hcfmusp.description.issue3
hcfmusp.description.volume12
hcfmusp.origemWOS
hcfmusp.origem.scopus2-s2.0-85058033103
hcfmusp.origem.wosWOS:000411388600002
hcfmusp.publisher.cityNEW ROCHELLE
hcfmusp.publisher.countryUSA
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