Tramadol wound infiltration is not different from intravenous tramadol in children: a randomized controlled trial

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dc.contributor Sistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP
dc.contributor.author GIRALDES, Ana Laura Albertoni
SOUSA, Angela Maria FMUSP-HC
SLULLITEL, Alexandre
GUIMARAES, Gabriel Magalhaes Nunes FMUSP-HC
SANTOS, Melina Genevieve Mary Egan FMUSP-HC
PINTO, Renata Evangelista FMUSP-HC
ASHMAWI, Hazem Adel FMUSP-HC
SAKATA, Rioko Kimiko
dc.date.issued 2016
dc.identifier.citation JOURNAL OF CLINICAL ANESTHESIA, v.28, p.62-66, 2016
dc.identifier.issn 0952-8180
dc.identifier.uri http://observatorio.fm.usp.br/handle/OPI/13545
dc.description.abstract Study Objective: The purpose of this trial was to assess if tramadol wound infiltration is superior to intravenous (IV) tramadol after minor surgical procedures in children because tramadol seems to have local anesthetic like effect. Design: Randomized double-blind controlled trial. Setting: Postanesthesia care unit. Patients: Forty children, American Society of Anesthesiologists physical status I or II, scheduled to elective inguinal hernia repair. Interventions: Children were randomly distributed in 1 of 2 groups: IV tramadol (group 1) or subcutaneous infiltration with tramadol (group 2). At the end of the surgery, group 1 received 2 mg/kg tramadol (3 mL) by IV route and 3-mL saline into the surgical wound; group 2 received 2 mg/kg tramadol (3 mL) into the surgical wound and 3-mL saline by IV route. Measurements: In the postanesthesia care unit, patients were evaluated for pain intensity, nausea and vomiting, time to first rescue medication, and total rescue morphine and dipyrone consumption. Main Results: Pain scores measured during the postanesthesia recovery time were similar between groups. Time to first rescue medication was shorter, but not statistically significant in the IV group. The total dose of rescue morphine and dipyrone was also similar between groups. Conclusions: We concluded that tramadol was effective in reducing postoperative pain in children, and there was no difference in pain intensity, nausea and vomiting, or somnolence regarding IV route or wound infiltration.
dc.language.iso eng
dc.publisher ELSEVIER SCIENCE INC
dc.relation.ispartof Journal of Clinical Anesthesia
dc.rights restrictedAccess
dc.subject Infiltration anesthesia; Tramadol; Intravenous administration; Postoperative pain; Hemioplasty
dc.subject.other regional anesthesia; nerve block; pain; levobupivacaine; analgesia; surgery; pharmacokinetics; lidocaine; repair
dc.title Tramadol wound infiltration is not different from intravenous tramadol in children: a randomized controlled trial
dc.type article
dc.rights.holder Copyright ELSEVIER SCIENCE INC
dc.description.group LIM/08
dc.identifier.doi 10.1016/j.jclinane.2015.08.009
dc.identifier.pmid 26440437
dc.type.category original article
dc.type.version publishedVersion
hcfmusp.author SOUSA, Angela Maria:HC:ICESP
hcfmusp.author GUIMARAES, Gabriel Magalhaes Nunes:HC:ICESP
hcfmusp.author SANTOS, Melina Genevieve Mary Egan:HU:SVANES-62
hcfmusp.author PINTO, Renata Evangelista:HU:SVANES-62
hcfmusp.author ASHMAWI, Hazem Adel:HC:ICHC
hcfmusp.author.external · GIRALDES, Ana Laura Albertoni:Univ Fed Sao Paulo, Pediat Anesthesia Unit, Dept Anesthesia, Div Surg, Sao Paulo, Brazil
· SLULLITEL, Alexandre:Santa Paula Hosp, Dept Anesthesia & Pain Management, Sao Paulo, Brazil
· SAKATA, Rioko Kimiko:Univ Fed Sao Paulo, Pediat Anesthesia Unit, Dept Anesthesia, Div Surg, Sao Paulo, Brazil
hcfmusp.origem.id 2-s2.0-84955344634
hcfmusp.origem.id WOS:000369194300013
hcfmusp.publisher.city NEW YORK
hcfmusp.publisher.country USA
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dc.description.index MEDLINE
dc.identifier.eissn 1873-4529
hcfmusp.citation.scopus 4
hcfmusp.citation.wos 4
hcfmusp.affiliation.country Brasil


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