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https://observatorio.fm.usp.br/handle/OPI/1395
Title: | Effects of repetitive transcranial magnetic stimulation on clinical, social, and cognitive performance in postpartum depression |
Authors: | MYCZKOWSKI, Martin Luiz; DIAS, Alvaro Machado; LUVISOTTO, Tatiana; ARNAUT, Debora; BELLINI, Bianca Boura; MANSUR, Carlos Gustavo; RENNO, Joel; TORTELLA, Gabriel; RIBEIRO, Philip Leite; MARCOLIN, Marco Antonio |
Citation: | NEUROPSYCHIATRIC DISEASE AND TREATMENT, v.8, p.491-500, 2012 |
Abstract: | Background: This randomized, placebo-controlled, double-blind pilot study evaluated the impact of repetitive transcranial magnetic stimulation (rTMS) on clinical, cognitive, and social performance in women suffering with postpartum depression. Methods: Fourteen patients were randomized to receive 20 sessions of sham rTMS or active 5 Hz rTMS over the left dorsolateral prefrontal cortex. Psychiatric clinical scales and a neuropsychological battery were applied at baseline (pretreatment), week 4 (end of treatment), and week 6 (follow-up, posttreatment week 2). Results: The active rTMS group showed significant improvement 2 weeks after the end of rTMS treatment (week 6) in Hamilton Depression Rating Scale (P = 0.020), Global Assessment Scale (P = 0.037), Clinical Global Impression (P = 0.047), and Social Adjustment Scale-Self Report-Work at Home (P = 0.020). Conclusion: This study suggests that rTMS has the potential to improve the clinical condition in postpartum depression, while producing marginal gains in social and cognitive function. |
Appears in Collections: | Artigos e Materiais de Revistas Científicas - HC/IPq Artigos e Materiais de Revistas Científicas - LIM/21 |
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