Management considerations for childhood-onset systemic lupus erythematosus patients and implications on therapy

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Citações na Scopus
32
Tipo de produção
article
Data de publicação
2016
Editora
TAYLOR & FRANCIS LTD
DOI
Indexadores
Scopus
Web of Science
PubMed
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Citação
EXPERT REVIEW OF CLINICAL IMMUNOLOGY, v.12, n.3, p.301-313, 2016
Projetos de Pesquisa
Unidades Organizacionais
Fascículo
Resumo
Childhood-onset systemic lupus erythematosus (cSLE) is a chronic inflammatory and autoimmune disease that may involve various organs and systems. This narrative review focuses on the recent evidence relating to cSLE management. The general management considerations of cSLE patients require the use of validated classification criteria, disease and health-related quality of life tools evaluation, as well as assessments of lupus nephritis biomarkers and cSLE quality indicators. The drug treatment for cSLE patients includes general supportive care and immunosuppressive therapy. Important implications on cSLE therapy are also updated such as infection, vaccination, infertility, pregnancy, contraception, dyslipidemia, physical activity, cancer, bone health, drug pharmacokinetics, adherence, academic outcomes, transition to adult care and cumulative organ damage.
Palavras-chave
Childhood-onset systemic lupus erythematosus, immunosuppressive, infection, vaccination, dyslipidemia, cancer, vitamin D, osteoporosis, exercise, fertility
URI
https://observatorio.fm.usp.br/handle/OPI/13957
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Coleções
Artigos e Materiais de Revistas Científicas - FM/MPE
Artigos e Materiais de Revistas Científicas - FM/MCM
Artigos e Materiais de Revistas Científicas - HC/ICHC
Artigos e Materiais de Revistas Científicas - HC/ICr
Artigos e Materiais de Revistas Científicas - LIM/17
Artigos e Materiais de Revistas Científicas - LIM/36
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