Please use this identifier to cite or link to this item: https://observatorio.fm.usp.br/handle/OPI/14370
Title: Cost-utility analysis of methylphenidate treatment for children and adolescents with ADHD in Brazil
Authors: MAIA, Carlos R.STELLA, Steffan F.WAGNER, FlaviaPIANCA, Thiago G.KRIEGER, Fernanda V.CRUZ, Luciane N.POLANCZYK, Guilherme V.ROHDE, Luis A.POLANCZYK, Carisi A.
Citation: REVISTA BRASILEIRA DE PSIQUIATRIA, v.38, n.1, p.30-38, 2016
Abstract: Objective: To perform a cost-utility analysis on the treatment of attention deficit hyperactivity disorder (ADHD) with methylphenidate immediate-release (MPH-1R) in children and adolescents from Brazil. Method: A Markov model was constructed to compare MPH-1R vs. no treatment. A 24 -week naturalistic study was conducted to collect transition probabilities and utility data. Effectiveness was expressed as quality -adjusted life -years (QALY), and costs reported in 2014 international dollars (1$). The perspective was the Brazilian Unified Health System as payer, and the time horizon was 6 years. Results: Of 171 patients, 73 provided information at baseline, and 56 at week 24. Considering the MPH-1R monthly cost of 1$ 38, the incremental cost-effectiveness ratio (ICER) of treatment was 1$ 9,103/QALY for children and 1$ 11,883/QALY for adolescents. In two-way sensitivity analysis, considering one Gross National Product per capita (1$ 11,530) as willingness-to-pay,a cost of no-treatment lower than 1$ 45/month would render MPH-IR a cost-saving strategy. Discussion: MPH-1R treatment of children and adolescents is cost-effective for ADHD patients from the Brazilian public health system perspective. Both patients and the healthcare system might benefit from such a strategy.
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Artigos e Materiais de Revistas Científicas - FM/MPS
Departamento de Psiquiatria - FM/MPS

Artigos e Materiais de Revistas Científicas - LIM/21
LIM/21 - Laboratório de Neuroimagem em Psiquiatria


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