Treatment of Depression in Older Adults

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art_BOTTINO_Treatment_of_Depression_in_Older_Adults_2012.PDF (172.48 KB)
Citações na Scopus
30
Tipo de produção
article
Data de publicação
2012
Editora
SPRINGER
DOI
Indexadores
Scopus
Web of Science
PubMed
Título da Revista
ISSN da Revista
Título do Volume
Autores
Autor de Grupo de pesquisa
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Citação
CURRENT PSYCHIATRY REPORTS, v.14, n.4, p.289-297, 2012
Projetos de Pesquisa
Unidades Organizacionais
Fascículo
Resumo
Depression is the most frequent mental disorder in older people, often causing emotional distress and reduced quality of life. Despite its clinical significance, depression remains underdiagnosed and inadequately treated in older patients. Regarding prognosis, data suggest that almost 70% of patients, treated long enough and with appropriate doses, recover from an index episode of depression. Antidepressants are efficient for treating depressed outpatients with several comorbid physical diseases as well as hospitalized patients, with selective serotonin reuptake inhibitors being the antidepressants of choice for older patients. Available data can guide pharmacological treatment in both the acute and maintenance stages, but further research is required to guide clinical strategies when remission is not achieved. Approaches for the management of resistance to treatment are summarized, including optimization strategies, drug changes, algorithms, and combined and augmentation pharmacological treatments. Finally, additional therapeutic choices such as electroconvulsive therapy, transcranial magnetic stimulation, and integrated psychotherapy are presented.
Palavras-chave
Depression, Aging, Older adults, Comorbidity, Polypharmacy, Antidepressants, Tricyclic antidepressants, Selective serotonin reuptake inhibitors, Serotonin and norepinephrine reuptake inhibitors, Monoamine oxidase inhibitors, Adverse effects, Treatment, Resistance to treatment, Recovery, Electroconvulsive therapy, Integrated psychotherapy
URI
https://observatorio.fm.usp.br/handle/OPI/1568
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Coleções
Artigos e Materiais de Revistas Científicas - LIM/21
Artigos e Materiais de Revistas Científicas - HC/IPq