Please use this identifier to cite or link to this item:
https://observatorio.fm.usp.br/handle/OPI/16055
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor | Sistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP | - |
dc.contributor.author | SILVA, Fernando P. | - |
dc.contributor.author | SCHMIDT, Andre P. | - |
dc.contributor.author | VALENTIN, Livia S. | - |
dc.contributor.author | PINTO, Katia O. | - |
dc.contributor.author | ZEFERINO, Suely P. | - |
dc.contributor.author | OSES, Jean P. | - |
dc.contributor.author | WIENER, Carolina D. | - |
dc.contributor.author | OTSUKI, Denise A. | - |
dc.contributor.author | TORT, Adriano B. L. | - |
dc.contributor.author | PORTELA, Luis V. | - |
dc.contributor.author | SOUZA, Diogo O. | - |
dc.contributor.author | AULER JR., Jose O. C. | - |
dc.contributor.author | CARMONA, Maria J. C. | - |
dc.date.accessioned | 2016-10-17T16:34:07Z | - |
dc.date.available | 2016-10-17T16:34:07Z | - |
dc.date.issued | 2016 | - |
dc.identifier.citation | EUROPEAN JOURNAL OF ANAESTHESIOLOGY, v.33, n.9, p.681-689, 2016 | - |
dc.identifier.issn | 0265-0215 | - |
dc.identifier.uri | https://observatorio.fm.usp.br/handle/OPI/16055 | - |
dc.description.abstract | BACKGROUND Postoperative cognitive dysfunction (POCD) may be related to the systemic inflammatory response and an increase in serum markers of brain injury such as S100B protein and neuron-specific enolase (NSE). OBJECTIVE The study aims to evaluate the association between POCD and serum levels of S100B and NSE after coronary artery bypass grafting surgery (CABG). DESIGN Prospective observational study. SETTING Single university teaching hospital. PATIENTS We investigated 88 patients undergoing CABG. MAIN OUTCOMES MEASURES Cognitive function was measured preoperatively, and at the 21st and 180th postoperative days (i.e. 6 months after surgery). S100B protein and NSE serum levels were evaluated preoperatively, after induction of anaesthesia, at the end of surgery and at 6 and 24 h after surgery. RESULTS The incidence of POCD was 26.1% at 21 days after surgery and 22.7% at 6 months after surgery. Increased serum levels of S100B protein and NSE were observed postoperatively and may indicate brain damage. CONCLUSION Although serum levels of S100B protein and NSE are both significantly increased postoperatively, our findings indicate that serum levels of S100B protein may be more accurate than NSE in the detection of POCD after CABG. | - |
dc.description.sponsorship | Foundation of Support to Research from Sao Paulo (FAPESP) [2007/55659-6] | - |
dc.description.sponsorship | Brazilian research agencies CNPq [482964/2001-1] | - |
dc.description.sponsorship | CAPES (CAPES/PROAP) [055/2011] | - |
dc.description.sponsorship | FAPERGS | - |
dc.description.sponsorship | UFRGS | - |
dc.description.sponsorship | USP | - |
dc.language.iso | eng | - |
dc.publisher | LIPPINCOTT WILLIAMS & WILKINS | - |
dc.relation.ispartof | European Journal of Anaesthesiology | - |
dc.rights | restrictedAccess | - |
dc.subject.other | cardiac-surgery | - |
dc.subject.other | off-pump | - |
dc.subject.other | s-100-beta protein | - |
dc.subject.other | elderly-patients | - |
dc.subject.other | serum-levels | - |
dc.subject.other | head-injury | - |
dc.subject.other | on-pump | - |
dc.subject.other | outcomes | - |
dc.subject.other | delirium | - |
dc.subject.other | markers | - |
dc.title | S100B protein and neuron-specific enolase as predictors of cognitive dysfunction after coronary artery bypass graft surgery A prospective observational study | - |
dc.type | article | - |
dc.rights.holder | Copyright LIPPINCOTT WILLIAMS & WILKINS | - |
dc.identifier.doi | 10.1097/EJA.0000000000000450 | - |
dc.identifier.pmid | 27433840 | - |
dc.subject.wos | Anesthesiology | - |
dc.type.category | original article | - |
dc.type.version | publishedVersion | - |
hcfmusp.author.external | SILVA, Fernando P.:Univ Sao Paulo, Fac Med, Hosp Clin, Dept Anaesthesia & Surg Intens Care, Sao Paulo, Brazil | - |
hcfmusp.author.external | SCHMIDT, Andre P.:Univ Fed Rio Grande do Sul, HCPA, Div Anaesthesia, Dept Anaesthesia & Perioperat Med, Porto Alegre, RS, Brazil; Fed Univ Hlth Sci Porto Alegre UFCSPA, Dept Surg, Porto Alegre, RS, Brazil; Univ Fed Rio Grande do Sul, Inst Hlth Sci ICBS, Dept Biochem, Porto Alegre, RS, Brazil | - |
hcfmusp.author.external | PINTO, Katia O.:Univ Sao Paulo, Fac Med, Hosp Clin, Dept Anaesthesia & Surg Intens Care, Sao Paulo, Brazil | - |
hcfmusp.author.external | OSES, Jean P.:Univ Catolica Pelotas, Ctr Ciencias Vida & Saude, Programa Posgrad Saude & Comportamento, Lab Neurociencias Clin, Pelotas, Brazil; Univ Catolica Pelotas, Hosp Univ San Francisco, Pelotas, Brazil | - |
hcfmusp.author.external | WIENER, Carolina D.:Univ Catolica Pelotas, Ctr Ciencias Vida & Saude, Programa Posgrad Saude & Comportamento, Lab Neurociencias Clin, Pelotas, Brazil; Univ Catolica Pelotas, Hosp Univ San Francisco, Pelotas, Brazil | - |
hcfmusp.author.external | TORT, Adriano B. L.:Fed Univ Rio Grande do Norte UFRN, Inst Brain, Natal, RN, Brazil | - |
hcfmusp.author.external | PORTELA, Luis V.:Univ Fed Rio Grande do Sul, Inst Hlth Sci ICBS, Dept Biochem, Porto Alegre, RS, Brazil | - |
hcfmusp.author.external | SOUZA, Diogo O.:Univ Fed Rio Grande do Sul, Inst Hlth Sci ICBS, Dept Biochem, Porto Alegre, RS, Brazil | - |
hcfmusp.description.beginpage | 681 | - |
hcfmusp.description.endpage | 689 | - |
hcfmusp.description.issue | 9 | - |
hcfmusp.description.volume | 33 | - |
hcfmusp.origem | WOS | - |
hcfmusp.origem.id | 2-s2.0-84982862015 | - |
hcfmusp.origem.id | WOS:000380765800010 | - |
hcfmusp.publisher.city | PHILADELPHIA | - |
hcfmusp.publisher.country | USA | - |
hcfmusp.relation.reference | Anderson RE, 2001, NEUROSURGERY, V48, P1255, DOI 10.1097/00006123-200106000-00012 | - |
hcfmusp.relation.reference | Bekker Alex Y, 2003, Best Pract Res Clin Anaesthesiol, V17, P259, DOI 10.1016/S1521-6896(03)00005-3 | - |
hcfmusp.relation.reference | Bohmer AE, 2011, NEUROSURGERY, V68, P1624, DOI 10.1227/NEU.0b013e318214a81f | - |
hcfmusp.relation.reference | Bruggemans EF, 2013, NETH HEART J, V21, P70, DOI 10.1007/s12471-012-0347-x | - |
hcfmusp.relation.reference | Chabok SY, 2012, J TRAUMA ACUTE CARE, V72, P1654, DOI 10.1097/TA.0b013e318246887e | - |
hcfmusp.relation.reference | Forn C, 2009, NEUROSCI LETT, V456, P11, DOI 10.1016/j.neulet.2009.03.081 | - |
hcfmusp.relation.reference | GEFFEN GM, 1994, ARCH CLIN NEUROPSYCH, V9, P303, DOI 10.1016/0887-6177(94)90018-3 | - |
hcfmusp.relation.reference | GORDON NG, 1978, PERCEPT MOTOR SKILL, V47, P191 | - |
hcfmusp.relation.reference | Goto T, 2014, J ANESTH, V28, P242, DOI 10.1007/s00540-013-1699-0 | - |
hcfmusp.relation.reference | Hovens IB, 2014, BRAIN BEHAV IMMUN, V38, P202, DOI 10.1016/j.bbi.2014.02.002 | - |
hcfmusp.relation.reference | Ingebrigtsen T, 2003, RESTOR NEUROL NEUROS, V21, P171 | - |
hcfmusp.relation.reference | Inouye SK, 2014, LANCET, V383, P911, DOI 10.1016/S0140-6736(13)60688-1 | - |
hcfmusp.relation.reference | Kofke WA, 2004, ANESTH ANALG, V99, P1323, DOI 10.1213/01.ANE.0000135345.03635.6A | - |
hcfmusp.relation.reference | Krenk L, 2010, ACTA ANAESTH SCAND, V54, P951, DOI 10.1111/j.1399-6576.2010.02268.x | - |
hcfmusp.relation.reference | Li YC, 2012, ACTA ANAESTH SCAND, V56, P595, DOI 10.1111/j.1399-6576.2011.02616.x | - |
hcfmusp.relation.reference | Linstedt U, 2002, ACTA ANAESTH SCAND, V46, P384, DOI 10.1034/j.1399-6576.2002.460409.x | - |
hcfmusp.relation.reference | Mahanna EP, 1996, ANN THORAC SURG, V61, P1342, DOI 10.1016/0003-4975(95)01095-5 | - |
hcfmusp.relation.reference | Marasco SF, 2008, EUR J CARDIO-THORAC, V33, P961, DOI 10.1016/j.ejcts.2008.03.022 | - |
hcfmusp.relation.reference | McDonagh DL, 2010, ANESTHESIOLOGY, V112, P852, DOI 10.1097/ALN.0b013e3181d31fd7 | - |
hcfmusp.relation.reference | Menge T, 2012, SCI TRANSL MED, V4, DOI 10.1126/scitranslmed.3004660 | - |
hcfmusp.relation.reference | Moller JT, 1998, LANCET, V351, P857, DOI 10.1016/S0140-6736(97)07382-0 | - |
hcfmusp.relation.reference | MURKIN JM, 1995, ANN THORAC SURG, V59, P1289, DOI 10.1016/0003-4975(95)00106-U | - |
hcfmusp.relation.reference | Newman MF, 2006, LANCET, V368, P694, DOI 10.1016/S0140-6736(06)69254-4 | - |
hcfmusp.relation.reference | Newman MF, 2001, NEW ENGL J MED, V344, P395, DOI 10.1056/NEJM200102083440601 | - |
hcfmusp.relation.reference | Peng LY, 2013, PLOS ONE, V8, DOI 10.1371/journal.pone.0079624 | - |
hcfmusp.relation.reference | Rasmussen LS, 1999, ACTA ANESTHESIOLOGIC, V43, P459 | - |
hcfmusp.relation.reference | Rudolph JL, 2010, ACTA ANAESTH SCAND, V54, P663, DOI 10.1111/j.1399-6576.2010.02236.x | - |
hcfmusp.relation.reference | Sauer AM, 2009, J ANESTH, V23, P256, DOI 10.1007/s00540-009-0744-5 | - |
hcfmusp.relation.reference | Selnes OA, 2012, NEW ENGL J MED, V366, P250, DOI 10.1056/NEJMra1100109 | - |
hcfmusp.relation.reference | Seo EH, 2011, ARCH GERONTOL GERIAT, V52, pE26, DOI 10.1016/j.archger.2010.04.008 | - |
hcfmusp.relation.reference | Seo EH, 2008, INT J GERIATR PSYCH, V23, P1020, DOI 10.1002/gps.2027 | - |
hcfmusp.relation.reference | Spinella PC, 2003, CRIT CARE MED, V31, P939, DOI 10.1097/01.CCM.0000053644.16336.52 | - |
hcfmusp.relation.reference | Steiner LA, 2011, EUR J ANAESTH, V28, P723, DOI 10.1097/EJA.0b013e328349b7db | - |
hcfmusp.relation.reference | Tamura A, 2011, ANN THORAC CARDIOVAS, V17, P33 | - |
hcfmusp.relation.reference | Tomic V, 2005, CIRCULATION, V112, P2912, DOI 10.1161/CIRCULATIONAHA.104.531152 | - |
hcfmusp.relation.reference | Tramontina F, 2006, CELL MOL NEUROBIOL, V26, P81, DOI 10.1007/s10571-006-9099-8 | - |
hcfmusp.relation.reference | van Harten AE, 2012, ANAESTHESIA, V67, P280, DOI 10.1111/j.1365-2044.2011.07008.x | - |
hcfmusp.relation.reference | van Munster BC, 2009, BMC NEUROL, V9, DOI 10.1186/1471-2377-9-21 | - |
hcfmusp.relation.reference | Waterloo K, 1997, ACTA NEUROCHIR, V139, P26, DOI 10.1007/BF01850864 | - |
hcfmusp.relation.reference | Woodford HJ, 2007, QJM-INT J MED, V100, P469, DOI 10.1093/qhned/gcn051 | - |
dc.description.index | MEDLINE | - |
dc.identifier.eissn | 1365-2346 | - |
hcfmusp.citation.scopus | 49 | - |
hcfmusp.scopus.lastupdate | 2024-03-29 | - |
Appears in Collections: | Artigos e Materiais de Revistas Científicas - FM/MCG Artigos e Materiais de Revistas Científicas - HC/InCor Artigos e Materiais de Revistas Científicas - LIM/08 Artigos e Materiais de Revistas Científicas - ODS/03 |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
art_SILVA_S100B_protein_and_neuronspecific_enolase_as_predictors_of_2016.PDF Restricted Access | publishedVersion (English) | 604.68 kB | Adobe PDF | View/Open Request a copy |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.