Comprehensive left ventricular mechanics analysis by speckle tracking echocardiography in Chagas disease

Imagem de Miniatura
Arquivos
art_LIMA_Comprehensive_left_ventricular_mechanics_analysis_by_speckle_tracking_2016.PDF (1.44 MB)
Citações na Scopus
11
Tipo de produção
article
Data de publicação
2016
Editora
BIOMED CENTRAL LTD
DOI
Indexadores
Scopus
Web of Science
PubMed
Título da Revista
ISSN da Revista
Título do Volume
Autores
VILLARRAGA, Hector R.
Autor de Grupo de pesquisa
Editores
Coordenadores
Organizadores
Citação
CARDIOVASCULAR ULTRASOUND, v.14, article ID 20, 11p, 2016
Projetos de Pesquisa
Unidades Organizacionais
Fascículo
Resumo
Background: Chagas disease (CD) is a frequent cause of dilated cardiomyopathy (CMP) in developing countries, leading to clinical heart failure and worse prognosis. Therefore, the development and evolution of this CMP has always been a major topic in numbers of previous studies. A comprehensive echocardiographic study of left ventricular (LV) mechanics, fully assessing myocardial contraction, has never been done before. This could help characterize and improve the understanding of the evolution of this prevalent CMP. Methods: A total of 47 chagasic and 84 control patients were included in this study and allocated in groups according to LV ejection fraction. 2D-Echocardiogram was acquired for LV mechanics analysis by speckle tracking echocardiography. Results: Mean age of chagasic individuals was 55y and 16 (34 %) were men. Significant difference was found in global longitudinal velocity analysis, with lower values in indeterminate form. In the group with severe systolic dysfunction, a paradoxical increase in longitudinal and apical radial displacements were demonstrated. In parallel, segmental analyzes highlighted lower values of radial displacement, strain and strain rate into inferior and inferolateral walls, with increase of these values in septal and anterior walls. Conclusion: Chagasic CMP has a vicarious pattern of contraction in the course of its evolution, defined by reduced displacement and strain into inferior and posterior walls with paradoxical increase in septal and anterior segments. Also, lower longitudinal velocities were demonstrated in CD indeterminate form, which may indicate an incipient myocardial injury.
Palavras-chave
Speckle tracking echocardiography, Cardiomyopathies, Cardiac mechanics, Strain
URI
https://observatorio.fm.usp.br/handle/OPI/16446
Referências
  1. Acquatella H, 2007, CIRCULATION, V115, P1124, DOI 10.1161/CIRCULATIONAHA.106.627323
  2. Amundsen BH, 2006, J AM COLL CARDIOL, V47, P789, DOI 10.1016/j.jacc.2005.10.040
  3. Andrade J.P., 2011, Arq. Bras. Cardiol., V97, P01, DOI 10.1590/S0066-782X2011001600001
  4. Bansal M, 2008, J AM SOC ECHOCARDIOG, V21, P887, DOI 10.1016/j.echo.2008.01.011
  5. Barbosa MM, 2014, ECHOCARDIOGR-J CARD, V31, P623, DOI 10.1111/echo.12426
  6. BARRETTO ACP, 1986, AM HEART J, V111, P307, DOI 10.1016/0002-8703(86)90144-4
  7. Barros MVL, 2001, ECHOCARDIOGR-J CARD, V18, P131, DOI 10.1046/j.1540-8175.2001.00131.x
  8. Becker M, 2006, HEART, V92, P1102, DOI 10.1136/hrt.2005.077107
  9. Biolo A, 2010, PROG CARDIOVASC DIS, V52, P300, DOI 10.1016/j.pcad.2009.11.008
  10. Edvardsen T, 2006, PROG CARDIOVASC DIS, V49, P207, DOI 10.1016/j.pcad.2006.08.008
  11. Garcia-Alvarez A, 2011, J CARD FAIL, V17, P1028, DOI 10.1016/j.cardfail.2011.08.007
  12. GUERRA HAC, 1987, AM HEART J, V113, P716
  13. Helle-Valle T, 2005, CIRCULATION, V112, P3149, DOI 10.1161/CIRCULATIONAHA.104.531558
  14. Hunt, 2006, CIRCULATION, V113, pE684
  15. Kim HK, 2007, J AM SOC ECHOCARDIOG, V20, P45, DOI 10.1016/j.echo.2006.07.007
  16. Lang RM, 2015, J AM SOC ECHOCARDIOG, V28, P1, DOI 10.1016/j.echo.2014.10.003
  17. Langeland S, 2005, CIRCULATION, V112, P2157, DOI 10.1161/CIRCULATIONAHA.105.554006
  18. MADY C, 1994, CIRCULATION, V90, P3098
  19. Mor-Avi V, 2011, EUR J ECHOCARDIOGR, V12, P167, DOI 10.1093/ejechocard/jer021
  20. Notomi Y, 2005, J AM COLL CARDIOL, V45, P2034, DOI 10.1016/j.jacc.2005.02.082
  21. Opdahl A, 2008, J AM SOC ECHOCARDIOG, V21, P1121, DOI 10.1016/j.echo.2008.06.012
  22. Park SJ, 2008, J AM SOC ECHOCARDIOG, V21, P1129, DOI 10.1016/j.echo.2008.04.002
  23. Pazin A, 2007, J AM SOC ECHOCARDIOG, V20, P1338, DOI 10.1016/j.echo.2007.04.029
  24. Pinto AD, 2007, ARQ BRAS CARDIOL, V89, P385, DOI 10.1590/S0066-782X2007001800006
  25. Rassi Salvador, 2005, Arq. Bras. Cardiol., V84, P309, DOI 10.1590/S0066-782X2005000400007
  26. Regueiro A, 2013, INT J CARDIOL, V165, P107, DOI 10.1016/j.ijcard.2011.07.089
  27. Rochitte CE, 2005, J AM COLL CARDIOL, V46, P1553, DOI 10.1016/j.jacc.2005.06.067
  28. Sambiase NV, 2010, INVEST CLIN, V51, P531
  29. Schmunis GA, 2010, ACTA TROP, V115, P14, DOI 10.1016/j.actatropica.2009.11.003
  30. Silva Carlos Eduardo Suaide, 2005, Arq. Bras. Cardiol., V84, P285, DOI 10.1590/S0066-782X2005000400003
  31. Takeuchi M, 2006, J AM SOC ECHOCARDIOG, V19, P1077, DOI 10.1016/j.ccho.2006.04.011
  32. van Dalen BM, 2008, AM J PHYSIOL-HEART C, V295, pH1705, DOI 10.1152/ajpheart.00513.2008
  33. Viotti RJ, 2004, HEART, V90, P655, DOI 10.1136/hrt.2003.018960
  34. Zhang Y, 2010, ECHOCARDIOGR-J CARD, V27, P1205, DOI 10.1111/j.1540-8175.2010.01226.x

Coleções
Artigos e Materiais de Revistas Científicas - HC/InCor
Carregar mais