Complications from carcinoid syndrome: review of the current evidence

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61
Tipo de produção
article
Data de publicação
2016
Editora
CANCER INTELLIGENCE LTD
DOI
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Scopus
Web of Science
PubMed
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Citação
ECANCERMEDICALSCIENCE, v.10, article ID 662, 17p, 2016
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Unidades Organizacionais
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Resumo
Patients with well-differentiated neuroendocrine tumours may develop carcinoid syndrome (CS), which is characterised by flushing, abdominal cramps, diarrhoea, and bronchospasms. In this scenario, long-term secretion of vasoactive substances-serotonin, tachynins, and others, may induce fibrogenic responses in local or distant tissues, leading to complications such as carcinoid heart disease (CHD), mesenteric and/or retroperitoneal fibrosis. Rare cases of lung/pleural fibrosis and scleroderma have also been described. Despite it not being well described yet, current evidence suggests the pathogenesis of such fibrogenic complications relies on signalling through 5-HT2B and TGF-beta 1. Medical management is still very limited and lacks prospective and randomised studies for definitive recommendations. Surgical procedures remain the best definitive treatment option for CHD and abdominal fibrosis. Recently, cognitive impairment has also been described as a potential consequence of CS. This review critically discusses the literature concerning the epidemiology, pathogenesis, clinical features, diagnosis, and treatment options for CS-related long-term complications.
Palavras-chave
carcinoid syndrome, complications, carcinoid heart disease, fibrosis
URI
https://observatorio.fm.usp.br/handle/OPI/17213
Referências
  1. Al Kharrat H, 2003, J CLIN GASTROENTEROL, V36, P87
  2. Becher G, 2013, CLIN EXP DERMATOL, V38, P310, DOI 10.1111/ced.12046
  3. Bell HK, 2005, BRIT J DERMATOL, V152, P71, DOI 10.1111/J.1365-2133.2004.06273.X
  4. Bergestuen DS, 2010, NEUROENDOCRINOLOGY, V92, P168, DOI 10.1159/000318014
  5. Bergestuen DS, 2010, BMC CANCER, V10, DOI 10.1186/1471-2407-10-6
  6. Bernheim AM, 2008, MAYO CLIN PROC, V83, P143, DOI 10.4065/83.2.143
  7. Bernheim AM, 2007, PROG CARDIOVASC DIS, V49, P439, DOI 10.1016/j.pcad.2006.12.002
  8. Bernheim AM, 2007, AM J CARDIOL, V99, P292, DOI 10.1016/j.amjcard.2006.07.092
  9. BERRY EM, 1974, GUT, V15, P34, DOI 10.1136/gut.15.1.34
  10. Bhattacharyya S, 2011, AM J CARDIOL, V107, P1221, DOI 10.1016/j.amjcard.2010.12.025
  11. Bhattacharyya S, 2010, CIRC-CARDIOVASC IMAG, V3, P103, DOI 10.1161/CIRCIMAGING.109.886846
  12. Bhattacharyya S, 2008, AM J CARDIOL, V101, P378, DOI 10.1016/j.amjcard.2007.08.045
  13. Bhattacharyya S, 2009, LANCET, V374, P577, DOI 10.1016/S0140-6736(09)60252-X
  14. Bhattacharyya S, 2008, AM J CARDIOL, V102, P938, DOI 10.1016/j.amjcard.2008.05.047
  15. Bhattacharyya S, 2013, J HEART VALVE DIS, V22, P400
  16. Biasco E, 2015, TUMORI, V101, pE24, DOI 10.5301/tj.5000259
  17. BIVENS CH, 1973, NEW ENGL J MED, V289, P844, DOI 10.1056/NEJM197310182891608
  18. Borman RA, 1997, ANN NY ACAD SCI, V812, P224, DOI 10.1111/j.1749-6632.1997.tb48183.x
  19. Bouma G, 2016, NEUROENDOCRINOLOGY, V103, P489, DOI 10.1159/000440621
  20. Capurso G, 2012, BRIT J SURG, V99, P1480, DOI 10.1002/bjs.8842
  21. Carrilho-Ferreira P, 2013, CAN J CARDIOL, V29, DOI 10.1016/j.cjca.2012.09.015
  22. Carter CA, 2015, CASE REP ONCOL, V8, P423, DOI 10.1159/000441122
  23. CASTIELLO RJ, 1972, ARCH DERMATOL, V105, P574, DOI 10.1001/archderm.105.4.574
  24. Castillo JG, 2008, BRIT J ANAESTH, V101, P618, DOI 10.1093/bja/aen237
  25. Castillo Javier G, 2013, Semin Cardiothorac Vasc Anesth, V17, P212, DOI 10.1177/1089253212465475
  26. Chambers AJ, 2010, WORLD J SURG, V34, P1356, DOI 10.1007/s00268-010-0404-9
  27. Chua Chiaco JM, 2013, CLEV CLIN J MED, V80, P638
  28. Condron ME, 2016, SURGERY, V159, P358, DOI 10.1016/j.surg.2015.05.036
  29. Connolly HM, 2015, J AM COLL CARDIOL, V66, P2189, DOI 10.1016/j.jacc.2015.09.014
  30. Connolly HM, 2002, CIRCULATION, V106, pI51, DOI 10.1161/01.cir.0000032884.55215.87
  31. CONNOLLY HM, 1995, J AM COLL CARDIOL, V25, P410, DOI 10.1016/0735-1097(94)00374-Y
  32. Denney WD, 1998, J AM COLL CARDIOL, V32, P1017, DOI 10.1016/S0735-1097(98)00354-4
  33. Dobson R, 2014, BRIT J CANCER, V111, P1703, DOI 10.1038/bjc.2014.468
  34. Dobson R, 2014, INT J CARDIOL, V173, P29, DOI 10.1016/j.ijcard.2014.02.037
  35. Dobson R, 2013, PLOS ONE, V8, DOI 10.1371/journal.pone.0073679
  36. DONOWITZ M, 1975, AM J DIG DIS, V20, P1115, DOI 10.1007/BF01070754
  37. Druce MR, 2010, QJM-INT J MED, V103, P177, DOI 10.1093/qjmed/hcp191
  38. Druce M, 2009, NAT REV ENDOCRINOL, V5, P276, DOI 10.1038/nrendo.2009.51
  39. Edwards NC, 2016, J CLIN ENDOCR METAB, V101, P182, DOI 10.1210/jc.2015-3295
  40. ENGELMAN K, 1967, NEW ENGL J MED, V277, P1103, DOI 10.1056/NEJM196711232772101
  41. Fabre A, 2008, EUR RESPIR J, V32, P426, DOI 10.1183/09031936.00126907
  42. Franzen D, 2009, CLIN CARDIOL, V32, P92, DOI [10.1002/clc.20260, DOI 10.1002/CLC.20260]
  43. Gelhorn HL, 2016, CLIN THER, V38, P759, DOI 10.1016/j.clinthera.2016.03.002
  44. Gershon MD, 2013, CURR OPIN ENDOCRINOL, V20, P14, DOI 10.1097/MED.0b013e32835bc703
  45. Grozinsky-Glasberg S, 2015, NEUROENDOCRINOLOGY, V101, P263, DOI 10.1159/000381930
  46. Guo LJ, 2014, ASIAN PAC J CANCER P, V15, P6679, DOI 10.7314/APJCP.2014.15.16.6679
  47. GUPTA A, 1985, Q J MED, V56, P367
  48. Gustafsson BI, 2008, INT J CARDIOL, V129, P318, DOI 10.1016/j.ijcard.2008.02.019
  49. Gustafsson BI, 2005, CIRCULATION, V111, P1517, DOI 10.1161/01.CIR.0000159356.42064.48
  50. Hafizi S, 2000, J HEART VALVE DIS, V9, P454
  51. HARGREAVES AD, 1994, INT J CARDIOL, V45, P150, DOI 10.1016/0167-5273(94)90274-7
  52. HARRIS AL, 1983, CANCER CHEMOTH PHARM, V10, P137, DOI 10.1007/BF00446228
  53. Hellman P, 2002, WORLD J SURG, V26, P991, DOI 10.1007/s00268-002-6630-z
  54. Hemminki K, 2001, CANCER, V92, P2204, DOI 10.1002/1097-0142(20011015)92:8<2204::AID-CNCR1564>3.0.CO;2-R
  55. HIMELMAN RB, 1989, AM J CARDIOL, V63, P347, DOI 10.1016/0002-9149(89)90344-5
  56. Hutcheson JD, 2011, PHARMACOL THERAPEUT, V132, P146, DOI 10.1016/j.pharmthera.2011.03.008
  57. Jackson LN, 2009, CLIN CANCER RES, V15, P2747, DOI 10.1158/1078-0432.CCR-08-2346
  58. JACOBSEN MB, 1995, EUR HEART J, V16, P263
  59. Janssen W, 2015, BIOMED RES INT, DOI 10.1155/2015/438403
  60. Jian B, 2002, AM J PATHOL, V161, P2111, DOI 10.1016/S0002-9440(10)64489-6
  61. KAHIL ME, 1964, ARCH INTERN MED, V114, P26
  62. Koopmans KP, 2005, J NUCL MED, V46, P1240
  63. KUCUK O, 1988, CANCER, V62, P1026, DOI 10.1002/1097-0142(19880901)62:5<1026::AID-CNCR2820620532>3.0.CO;2-E
  64. Kulke MH, 2015, EUR J CANCER, V51, pS728
  65. Kulke MH, 2015, NANETS S
  66. KVOLS LK, 1994, ANN NY ACAD SCI, V733, P464, DOI 10.1111/j.1749-6632.1994.tb17296.x
  67. KVOLS LK, 1985, NEW ENGL J MED, V313, P1229
  68. Lafaras CT, 2010, ONKOLOGIE, V33, P300, DOI 10.1159/000313596
  69. Lillegard JB, 2011, J AM COLL SURGEONS, V213, P130, DOI 10.1016/j.jamcollsurg.2011.03.029
  70. Makridis C, 1996, WORLD J SURG, V20, P900
  71. Mansencal N, 2006, AM HEART J, V151, DOI 10.1016/j.ahj.2006.02.019
  72. Mansencal N, 2010, AM J CARDIOL, V105, P527, DOI 10.1016/j.amjcard.2009.10.023
  73. Mansencal N, 2008, AM J CARDIOL, V101, P1035, DOI 10.1016/j.amjcard.2007.11.056
  74. Massimino K, 2013, J SURG ONCOL, V107, P842, DOI 10.1002/jso.23323
  75. MILLER RR, 1995, AM J SURG PATHOL, V19, P653, DOI 10.1097/00000478-199506000-00005
  76. Modlin IM, 2004, AM J GASTROENTEROL, V99, P2466, DOI 10.1111/j.1572-0241.2004.40507.x
  77. Modlin IM, 2005, GASTROENTEROLOGY, V128, P1717, DOI 10.1053/j.gastro.2005.03.038
  78. Mokhles P, 2012, EUR J CARDIO-THORAC, V41, P1278, DOI 10.1093/ejcts/ezr227
  79. Moller JE, 2003, NEW ENGL J MED, V348, P1005, DOI 10.1056/NEJMoa021451
  80. Moller JE, 2005, CIRCULATION, V112, P3320, DOI 10.1161/CIRCULATIONAHA.105.553750
  81. MONERETVAUTRIN DA, 1993, BRIT J ANAESTH, V71, P609, DOI 10.1093/bja/71.4.609
  82. MORGAN JG, 1974, ANN SURG, V180, P720, DOI 10.1097/00000658-197411000-00003
  83. Morrisroe K, 2012, INTERN MED J, V42, P342, DOI 10.1111/j.1445-5994.2012.02719.x
  84. MOSS SF, 1993, Q J MED, V86, P49
  85. Musunuru S, 2005, J SURG RES, V126, P102, DOI 10.1016/j.jss.2005.01.003
  86. Nebigil CG, 2003, CIRCULATION, V107, P3223, DOI 10.1161/01.CIR.0000074224.57016.01
  87. Nebigil CG, 2000, P NATL ACAD SCI USA, V97, P9508, DOI 10.1073/pnas.97.17.9508
  88. OATES JA, 1964, LANCET, V1, P514
  89. OHRI SK, 1994, ANN THORAC SURG, V58, P1161
  90. Pape UF, 2012, NEUROENDOCRINOLOGY, V95, P135, DOI 10.1159/000335629
  91. Pasieka JL, 2014, ANN SURG, V259, P355, DOI 10.1097/SLA.0b013e318288ff6d
  92. Patel C, 2014, AM HEART J, V167, P789, DOI 10.1016/j.ahj.2014.03.018
  93. Pavel ME, 2011, LANCET, V378, P2005, DOI 10.1016/S0140-6736(11)61742-X
  94. PELLIKKA PA, 1993, CIRCULATION, V87, P1188
  95. PETRIK PK, 1989, AM J FOREN MED PATH, V10, P146, DOI 10.1097/00000433-198906000-00011
  96. Plockinger U, 2009, NEUROENDOCRINOLOGY, V90, P190, DOI 10.1159/000225947
  97. Propst J W, 1994, J Cardiothorac Vasc Anesth, V8, P209, DOI 10.1016/1053-0770(94)90065-5
  98. Rajamannan NM, 2001, J HEART VALVE DIS, V10, P827
  99. RATNAVEL RC, 1994, CLIN EXP DERMATOL, V19, P83, DOI 10.1111/j.1365-2230.1994.tb01126.x
  100. RIDKER PM, 1991, AM HEART J, V121, P1835, DOI 10.1016/0002-8703(91)90045-J
  101. Rinke A, 2009, J CLIN ONCOL, V27, P4656, DOI 10.1200/JCO.2009.22.8510
  102. Rinke A, 2017, NEUROENDOCRINOLOGY, V104, P26
  103. ROBIOLIO PA, 1995, CIRCULATION, V92, P790
  104. ROBIOLIO PA, 1995, AM J CARDIOL, V75, P485, DOI 10.1016/S0002-9149(99)80586-4
  105. Russo S, 2004, PSYCHOSOM MED, V66, P422, DOI 10.1097/01.psy.0000126204.97565.91
  106. Sakai D, 2000, PATHOL INT, V50, P404, DOI 10.1046/j.1440-1827.2000.01053.x
  107. Shah GM, 2005, AM J GASTROENTEROL, V100, P2307, DOI 10.1111/j.1572-0241.2005.00268.x
  108. Simula DV, 2002, MAYO CLIN PROC, V77, P139
  109. Soga J, 1999, J EXP CLIN CANC RES, V18, P133
  110. Soga J, 2003, J EXP CLIN CANC RES, V22, P517
  111. SWAIN CP, 1976, GASTROENTEROLOGY, V71, P484
  112. Tamagno G, 2007, INTERNAL MED, V46, P425, DOI 10.2169/internalmedicine.46.6367
  113. THORBURN CW, 1983, AM J CARDIOL, V51, P1128, DOI 10.1016/0002-9149(83)90357-0
  114. VINIK AI, 1989, GASTROENTEROL CLIN N, V18, P865
  115. Walsh JS, 2013, J CLIN ENDOCR METAB, V98, P2902, DOI 10.1210/jc.2012-4174
  116. WALTENBERGER J, 1993, AM J PATHOL, V142, P71
  117. Weingarten TN, 2007, ANESTH ANALG, V105, P1192, DOI 10.1213/01.ane.0000284704.57806.0b
  118. Westberg G, 2001, BRIT J SURG, V88, P865, DOI 10.1046/j.0007-1323.2001.01798.x
  119. Yao JC, 2008, J CLIN ONCOL, V26, P3063, DOI 10.1200/JCO.2007.15.4377
  120. Zacks J, 2016, 13 ANN ENETS C
  121. ZARAFONETIS CJD, 1958, AM J MED SCI, V236, P1, DOI 10.1097/00000441-195807000-00001
  122. Zuetenhorst J, 2004, BRIT J CANCER, V90, P2073, DOI 10.1038/sj.bjc.6601816
  123. Zuetenhorst JM, 2003, CANCER, V97, P1609, DOI 10.1002/cncr.11226

Coleções
Artigos e Materiais de Revistas Científicas - HC/ICESP
Artigos e Materiais de Revistas Científicas - LIM/24
Artigos e Materiais de Revistas Científicas - ODS/03