Angiosarcoma in HIV-negative patients is not associated with HHV-8

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dc.contributor Sistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP
dc.contributor.author AVANCINI, Joao FMUSP-HC
CHERUBIM, Andre Pires Zanata
OLIVEIRA, Cristina Mendes de FMUSP-HC
VALENTE, Neusa Yuriko Sakai FMUSP-HC
FESTA NETO, Cyro FMUSP-HC
SANCHES, Jose Antonio FMUSP-HC
PAZZINI, Renato FMUSP-HC
SUMITA, Laura Masami FMUSP-HC
PANNUTI, Claudio Sergio FMUSP-HC
dc.date.issued 2016
dc.identifier.citation ANAIS BRASILEIROS DE DERMATOLOGIA, v.91, n.6, p.738-741, 2016
dc.identifier.issn 0365-0596
dc.identifier.uri http://observatorio.fm.usp.br/handle/OPI/18807
dc.description.abstract BACKGROUND: Angiosarcoma is an aggressive, malignant neoplasm of vascular or lymphatic origin. Herpes virus 8 (HHV-8) is a member of the herpes family with a tropism for endothelial cells and it has been proven to induce vascular neoplasms, such as Kaposi's sarcoma. The role of HHV-8 in the pathogenesis of angiosarcoma has not been well defined. OBJECTIVE: To investigate the relationship between the presence of HHV-8 and angiosarcoma. METHODS: In this study, the team investigated the relationship between the presence of HHV-8, as determined by polymerase chain reaction, and angiosarcoma, using samples from patients with epidemic Kaposi's sarcoma as controls. RESULTS: While all control cases with epidemic Kaposi's sarcoma were positive for HHV-8, none of the angiosarcoma cases was. CONCLUSION: These findings support most previous studies that found no association between HHV-8 and angiosarcoma.
dc.language.iso eng
dc.publisher SOC BRASILEIRA DERMATOLOGIA
dc.relation.ispartof Anais Brasileiros de Dermatologia
dc.rights openAccess
dc.subject Hemangiosarcoma; Herpesvirus 8; human; HIV
dc.subject.other sarcoma-associated herpesvirus; kaposis-sarcoma; dna-sequences; human-herpesvirus-8 dna; absence; infection; lesions; kshv; populations; tumors
dc.title Angiosarcoma in HIV-negative patients is not associated with HHV-8
dc.type article
dc.rights.holder Copyright SOC BRASILEIRA DERMATOLOGIA
dc.description.group LIM/52
dc.description.group LIM/53
dc.identifier.doi 10.1590/abd1806-4841.20164730
dc.identifier.pmid 28099593
dc.type.category original article
dc.type.version publishedVersion
hcfmusp.author AVANCINI, Joao:HC:ICHC
hcfmusp.author OLIVEIRA, Cristina Mendes de:HC:LIM/52
hcfmusp.author VALENTE, Neusa Yuriko Sakai:HC:ICHC
hcfmusp.author FESTA NETO, Cyro:FM:MDT
hcfmusp.author SANCHES, Jose Antonio:FM:MDT
hcfmusp.author PAZZINI, Renato:HC:ICHC
hcfmusp.author SUMITA, Laura Masami:HC:LIM/52
hcfmusp.author PANNUTI, Claudio Sergio:FM:MIP
hcfmusp.author.external · CHERUBIM, Andre Pires Zanata:Univ Sao Paulo, Sao Paulo, SP, Brazil
hcfmusp.origem.id WOS:000392746000004
hcfmusp.origem.id 2-s2.0-85009823739
hcfmusp.origem.id SCIELO:S0365-05962016000600738
hcfmusp.publisher.city RIO DE JANEIRO RJ
hcfmusp.publisher.country BRAZIL
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dc.description.index MEDLINE
dc.identifier.eissn 1806-4841
hcfmusp.citation.scopus 0
hcfmusp.citation.wos 0
hcfmusp.affiliation.country Brasil


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