HOW CAN WE ESTIMATE SEPSIS INCIDENCE AND MORTALITY?

Imagem de Miniatura
Arquivos
art_GOBATTO_HOW_CAN_WE_ESTIMATE_SEPSIS_INCIDENCE_AND_MORTALITY_2017.PDF (232.86 KB)
Citações na Scopus
22
Tipo de produção
article
Data de publicação
2017
DOI
Scopus
Web of Science
PubMed
Título da Revista
ISSN da Revista
Título do Volume
Editora
LIPPINCOTT WILLIAMS & WILKINS
Autores
Citação
SHOCK, v.47, n.1, suppl.1, p.6-11, 2017
Projetos de Pesquisa
Unidades Organizacionais
Fascículo
Resumo
Sepsis is one of the oldest and complex syndromes in medicine that has been in debate for over two millennia. Valid and comparable data on the population burden of sepsis constitute an essential resource for guiding health policy and resource allocation. Despite current epidemiological data suggesting that the global burden of sepsis is huge, the knowledge of its incidence, prevalence, mortality, and case-fatality rates is subject to several flaws. The objective of this narrative review is to assess how sepsis incidence and mortality can be estimated, providing examples on how it has been done so far in medical literature and discussing its possible biases. Results of recent studies suggest that sepsis incidence rates are increasing consistently during the last decades. Although estimates might be biased, this probably reflects a real increase in incidence over time. Nevertheless, case fatality rates have decreased, which is a probable reflex of advances in critical care provision to this very sick population at high risk of death. This conclusion can only be drawn with a reasonable degree of certainty for high-income countries. Conversely, adequately designed studies from middle-and low-income countries are urgently needed. In these countries, sepsis incidence and case-fatality rates could be disproportionally higher due to health care provision constraints and ineffective preventive measures.
Palavras-chave
Epidemiology, incidence, mortality, sepsis, septic shock, severe sepsis
URI
https://observatorio.fm.usp.br/handle/OPI/20260
Referências
  1. Angus DC, 2015, INTENS CARE MED, V41, P1549, DOI 10.1007/s00134-015-3822-1
  2. Angus DC, 2001, CRIT CARE MED, V29, P1303, DOI 10.1097/00003246-200107000-00002
  3. Angus DC, 2013, NEW ENGL J MED, V369, P840, DOI 10.1056/NEJMra1208623
  4. Beale R, 2009, INFECTION, V37, P222, DOI 10.1007/s15010-008-8203-z
  5. BONE RC, 1992, CHEST, V101, P1644, DOI 10.1378/chest.101.6.1644
  6. Bouza Carmen, 2014, BMC Infect Dis, V14, P3863, DOI 10.1186/s12879-014-0717-7
  7. Brower RG, 2000, NEW ENGL J MED, V342, P1301
  8. Davis JS, 2011, MED J AUSTRALIA, V194, P519
  9. Dombrovskiy VY, 2007, CRIT CARE MED, V35, P1244, DOI 10.1097/01.CCM.0000261890.41311.E9
  10. Esteban A, 2007, CRIT CARE MED, V35, P1284, DOI 10.1097/01.CCM.0000260960.94300.DE
  11. Flaatten H, 2004, CRIT CARE, V8, pR180, DOI 10.1186/cc2867
  12. Fleischmann C, 2016, AM J RESP CRIT CARE, V193, P259, DOI 10.1164/rccm.201504-0781OC
  13. Gaieski DF, 2013, CRIT CARE MED, V41, P1167, DOI 10.1097/CCM.0b013e31827c09f8
  14. Investigators A, 2014, NEW ENGL J MED, V371, P1496, DOI 10.1056/NEJM0A1404380
  15. Jawad Issrah, 2012, J Glob Health, V2, P010404, DOI 10.7189/jogh.02.010404
  16. Kaukonen KM, 2015, NEW ENGL J MED, V372, P1629, DOI 10.1056/NEJMoa1415236
  17. Kaukonen KM, 2014, JAMA-J AM MED ASSOC, V311, P1308, DOI 10.1001/jama.2014.2637
  18. Kauss IAM, 2010, BRAZ J INFECT DIS, V14, P264, DOI 10.1590/S1413-86702010000300011
  19. Klouwenberg PMCK, 2015, CRIT CARE, V19, DOI 10.1186/s13054-015-1035-1
  20. Lagu T, 2012, CRIT CARE MED, V40, P754, DOI 10.1097/CCM.0b013e318232db65
  21. Lindenauer PK, 2012, JAMA-J AM MED ASSOC, V307, P1405, DOI 10.1001/jama.2012.384
  22. Martin GS, 2006, CRIT CARE MED, V34, P15, DOI 10.1097/01.CCM.0000194535.82812.BA
  23. Martin GS, 2003, NEW ENGL J MED, V348, P1546, DOI 10.1056/NEJMoa022139
  24. Mouncey PR, 2015, NEW ENGL J MED, V372, P1301, DOI 10.1056/NEJMoa1500896
  25. Noritomi DT, 2014, INTENS CARE MED, V40, P182, DOI 10.1007/s00134-013-3131-5
  26. Pro CI, 2014, NEW ENGL J MED, V370, P1683, DOI 10.1056/NEJMOA1401602
  27. Rodriguez F, 2011, CRIT CARE MED, V39, P1675, DOI 10.1097/CCM.0b013e318218a35e
  28. Shen HN, 2010, CHEST, V138, P298, DOI 10.1378/chest.09-2205
  29. Silva E, 2004, CRIT CARE, V8, pR251, DOI 10.1186/cc2892
  30. Stehr SN, 2013, SHOCK, V39, P3, DOI 10.1097/SHK.0b013e31828fad61
  31. Sundararajan V, 2005, CRIT CARE MED, V33, P71, DOI 10.1097/01.CCM.0000150027.98160.80
  32. Taniguchi LU, 2014, CRIT CARE, V18, DOI 10.1186/s13054-014-0608-8
  33. van Gestel A, 2004, CRIT CARE, V8, pR153, DOI 10.1186/cc2858
  34. Wilhelms SB, 2010, CRIT CARE MED, V38, P1442, DOI 10.1097/CCM.0b013e3181de4406

Coleções
Artigos e Materiais de Revistas Científicas - HC/ICHC
Artigos e Materiais de Revistas Científicas - LIM/51