THE EPIDEMIOLOGY OF SEPSIS IN CHILDHOOD

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Arquivos
art_SOUZA_THE_EPIDEMIOLOGY_OF_SEPSIS_IN_CHILDHOOD_2017.PDF (141.87 KB)
Citações na Scopus
33
Tipo de produção
article
Data de publicação
2017
Editora
LIPPINCOTT WILLIAMS & WILKINS
DOI
Indexadores
Scopus
Web of Science
PubMed
Título da Revista
ISSN da Revista
Título do Volume
Autores
SOUZA, Daniela Carla de
FARIA, Lucilia Santana
Autor de Grupo de pesquisa
Editores
Coordenadores
Organizadores
Citação
SHOCK, v.47, n.1, suppl.1, p.2-5, 2017
Projetos de Pesquisa
Unidades Organizacionais
Fascículo
Resumo
Background: Sepsis, or systemic inflammatory response to infection, is a major childhood disease and a common cause of death in children. Despite its importance, a global perspective on the epidemiology and mortality of pediatric sepsis across the world is still lacking. Methods: A non-systematic review of the medical articles published in Medline from 2005 to 2015. Results: Studies suggest that there has been a rise in the number of pediatric sepsis cases along the last two decades, which may relate to the increased survival of preterm and low birth-weight infants and children with severe chronic conditions. Children living in low-income countries represent a vulnerable population for sepsis. Despite several initiatives to improve the diagnosis and early treatment of pediatric sepsis, the mortality resulting from pediatric sepsis remains high, ranging from 5% to 40%. Poor outcomes, however, do not seem to be related to the limitation of resources but to the delay in the recognition and early treatment of sepsis. Conclusions: Educational efforts aiming to increase the awareness on sepsis by the general public and the adherence to the treatment guidelines by healthcare providers may result in significant improvements in sepsis survival. The global attention to pediatric sepsis, however, can only be achieved with the standardization of the definitions and the use of simple and sensitive diagnostic criteria that incorporate the differences in the necessities among different settings and the availability of local resources.
Palavras-chave
Child, incidence, mortality, outcome, prevalence, sepsis, septic shock, severe sepsis
URI
https://observatorio.fm.usp.br/handle/OPI/20389
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Coleções
Artigos e Materiais de Revistas Científicas - HU