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https://observatorio.fm.usp.br/handle/OPI/2225
Title: | Primary neural leprosy: systematic review |
Authors: | GARBINO, Jose Antonio; MARQUES JR., Wilson; BARRETO, Jaison Antonio; HEISE, Carlos Otto; RODRIGUES, Marcia Maria Jardim; ANTUNES, Sergio L.; SOARES, Cleverson Teixeira; FLORIANO, Marcos Cesar; NERY, Jose Augusto; TRINDADE, Maria Angelo Bianconcini; CARVALHO, Noemia Barbosa; ANDRADA, Nathalia Carvalho de; BARREIRA, Amilton Antunes; VIRMOND, Marcos da Cunha Lopes |
Citation: | ARQUIVOS DE NEURO-PSIQUIATRIA, v.71, n.6, p.397-404, 2013 |
Abstract: | The authors proposed a systematic review on the current concepts of primary neural leprosy by consulting the following online databases: MEDLINE, Lilacs/SciELO, and Embase. Selected studies were classified based on the degree of recommendation and levels of scientific evidence according to the ""Oxford Centre for Evidence-based Medicine"". The following aspects were reviewed: cutaneous clinical and laboratorial investigations, i.e. skin clinical exam, smears, and biopsy, and Mitsuda's reaction; neurological investigation (anamnesis, electromyography and nerve biopsy); serological investigation and molecular testing, i.e. serological testing for the detection of the phenolic glycolipid 1 (PGL-1) and the polymerase chain reaction (PCR); and treatment (classification criteria for the definition of specific treatment, steroid treatment, and cure criteria). |
Appears in Collections: | Artigos e Materiais de Revistas Científicas - FM/Outros Artigos e Materiais de Revistas Científicas - ODS/03 |
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