Livedoid vasculopathy: an intringuing cutaneous disease

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dc.contributor Sistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP
dc.contributor.author CRIADO, Paulo Ricardo FMUSP-HC
RIVITTI, Evandro Ararigboia FMUSP-HC
SOTTO, Mirian Nacagami FMUSP-HC
VALENTE, Neusa Yuriko Sakai FMUSP-HC
AOKI, Valeria FMUSP-HC
CARVALHO, Jozelio Freire de FMUSP-HC
VASCONCELLOS, Cidia FMUSP-HC
dc.date.issued 2011
dc.identifier.citation ANAIS BRASILEIROS DE DERMATOLOGIA, v.86, n.5, p.961-977, 2011
dc.identifier.issn 0365-0596
dc.identifier.uri http://observatorio.fm.usp.br/handle/OPI/22950
dc.description.abstract Livedoid vasculopathy is a skin disease that occludes the blood vessels of the dermis. It has a pauciinflammatory or non-inflammatory nature. It is characterized by the presence of macular or papular, erythematous-purpuric lesions affecting the legs, especially the ankles and feet, and producing intensely painful ulcerations, which cause white atrophic scars called ""atrophie blanche"". This review includes studies and case reports found in the medical literature regarding the etiopathogenic associations of the disease, particularly those related to thrombophilia, their histopathological findings and the therapeutic approaches used in the difficult clinical management of these cases.
dc.description.abstract A vasculopatia livedoide é uma afecção cutânea oclusiva dos vasos sanguíneos da derme, de caráter pauci-inflamatório ou não-inflamatório. Caracteriza-se pela presença de lesões maculosas ou papulosas, eritêmato-purpúricas, nas pernas, especialmente nos tornozelos e pés, as quais produzem ulcerações intensamente dolorosas, que originam cicatrizes atróficas esbranquiçadas, denominadas "atrofia branca". Nesta revisão, abordamos os estudos e relatos de caso da literatura médica referentes às associações etiopatogênicas da doença, particularmente as que se referem aos estados de trombofilia, seus achados histopatológicos e abordagens terapêuticas empregadas na difícil condução clínica destes casos.
dc.language.iso por
dc.language.iso eng
dc.publisher SOC BRASILEIRA DERMATOLOGIA
dc.relation.ispartof Anais Brasileiros de Dermatologia
dc.rights openAccess
dc.subject Leg ulcer; Livedo reticularis; Thrombophilia; Thrombosis; Venous thrombosis; Livedo reticular; Trombofilia; Trombose; Trombose venosa; Úlcera da perna
dc.subject.other molecular-weight heparin; plasminogen-activator inhibitor-1; segmental hyalinizing vasculitis; promoter homozygosity 4g/4g; idiopathic atrophy blanche; v-leiden mutation; low-dose danazol; intravenous immunoglobulin; antiphospholipid syndrome; prothrombin g20210a
dc.title Livedoid vasculopathy: an intringuing cutaneous disease
dc.title.alternative Vasculopatia livedoide: uma doença cutânea intrigante
dc.type article
dc.rights.holder Copyright SOC BRASILEIRA DERMATOLOGIA
dc.description.group LIM/53
dc.description.group LIM/56
dc.identifier.pmid 22147037
dc.type.category review
dc.type.version publishedVersion
hcfmusp.author CRIADO, Paulo Ricardo:HC:LIM/53
hcfmusp.author RIVITTI, Evandro Ararigboia:FM:MDT
hcfmusp.author SOTTO, Mirian Nacagami:FM:MDT
hcfmusp.author VALENTE, Neusa Yuriko Sakai:HC:ICHC
hcfmusp.author AOKI, Valeria:FM:MDT
hcfmusp.author CARVALHO, Jozelio Freire de:HC:ICHC
hcfmusp.author VASCONCELLOS, Cidia:FM:
hcfmusp.origem.id WOS:000297756500015
hcfmusp.origem.id 2-s2.0-83755195645
hcfmusp.publisher.city RIO DE JANEIRO RJ
hcfmusp.publisher.country BRAZIL
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dc.description.index MEDLINE
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