In utero exposure to air pollution lowers erythrocyte antioxidant defense and decreases weight in adult mice
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Tipo de produção
article
Data de publicação
2011
Editora
ELSEVIER SCIENCE BV
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Título do Volume
Autores
ABE, Karina Camasmie
BRANDAO, Leticia de Campos
TUFIK, Sergio
D'ALMEIDA, Vania
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Citação
ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY, v.32, n.2, p.315-318, 2011
Resumo
In this study, we tested the influence of ambient air pollution on different phases of development of adult mice. With respect to adult weight, the animals that had spent their in utero period exposed to pollution showed less weight gain over their lifetime, as well as lower activity levels of the antioxidant enzymes catalase, superoxide dismutase (SOD) and glutathione peroxidase (GPx). Our study suggests that contact with atmospheric pollutants during the foetal period produces important changes on enzymatic erythrocyte antioxidant defense and weight in adult mice.
Palavras-chave
Air pollution, Antioxidant defense, Catalase, Superoxide dismutase, Glutathione peroxidase
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