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DC Field | Value | Language |
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dc.contributor | Sistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP | - |
dc.contributor.author | MATTOS, Paulo | - |
dc.contributor.author | LOUZA, Mario Rodrigues | - |
dc.contributor.author | PALMINI, Andre Luis Fernandes | - |
dc.contributor.author | OLIVEIRA, Irismar Reis de | - |
dc.contributor.author | ROCHA, Fabio Lopes | - |
dc.date.accessioned | 2013-09-23T16:55:07Z | - |
dc.date.available | 2013-09-23T16:55:07Z | - |
dc.date.issued | 2013 | - |
dc.identifier.citation | JOURNAL OF ATTENTION DISORDERS, v.17, n.5, p.444-448, 2013 | - |
dc.identifier.issn | 1087-0547 | - |
dc.identifier.uri | https://observatorio.fm.usp.br/handle/OPI/2404 | - |
dc.description.abstract | The available literature provides few studies on the effectiveness of methylphenidate in improving quality of life in individuals with ADHD. Objective: To assess the effectiveness of Methyphenidate OROS formulation (OROS MPH) through QoL in adults with ADHD. Method: A 12-week, multicenter, open-label trial involving 60 patients was used. The measures used were Adult Self-Rating Scale, Adult ADHD Quality of Life Scale (AAQoL), State and Trait Anxiety Inventory (STAI), Hamilton Depression Rating Scale (HAM-D), Clinical Global Impression (CGI), and safety measures. A significance statistic level of 5% was adopted. Results: Analyses included 60 patients (66.7% male; M age = 31.1 years) for safety and 58 patients for effectiveness. All AAQoL subscales improved from baseline to Week 12 (p < .0001), as well as the Total AAQoL (p < .0001). A significant reduction on Clinical Global Impression-Improvement (CGI-I), HAM-D, STAI, and ASRS scores was observed (p < .0001). No serious adverse event was reported. Conclusion: Treatment of adult ADHD patients with OROS MPH improves QoL. | - |
dc.description.sponsorship | Janssen-Cilag Brazil | - |
dc.language.iso | eng | - |
dc.publisher | SAGE PUBLICATIONS INC | - |
dc.relation.ispartof | Journal of Attention Disorders | - |
dc.rights | restrictedAccess | - |
dc.subject | ADHD | - |
dc.subject | adult ADHD | - |
dc.subject | stimulants | - |
dc.subject.other | attention-deficit/hyperactivity disorder | - |
dc.subject.other | questionnaire aaqol | - |
dc.subject.other | portuguese version | - |
dc.subject.other | reliability | - |
dc.subject.other | impairment | - |
dc.subject.other | validation | - |
dc.subject.other | diagnosis | - |
dc.subject.other | symptoms | - |
dc.title | A Multicenter, Open-Label Trial to Evaluate the Quality of Life in Adults With ADHD Treated With Long-Acting Methylphenidate (OROS MPH): Concerta Quality of Life (CONQoL) Study | - |
dc.type | article | - |
dc.rights.holder | Copyright SAGE PUBLICATIONS INC | - |
dc.identifier.doi | 10.1177/1087054711434772 | - |
dc.identifier.pmid | 22334621 | - |
dc.subject.wos | Psychology, Developmental | - |
dc.subject.wos | Psychiatry | - |
dc.type.category | original article | - |
dc.type.version | publishedVersion | - |
hcfmusp.author.external | MATTOS, Paulo:Univ Fed Rio de Janeiro, Inst DOr Res & Learning, BR-22280010 Rio De Janeiro, RJ, Brazil; Inst DOr Res & Learning, Rio De Janeiro, Brazil | - |
hcfmusp.author.external | PALMINI, Andre Luis Fernandes:Pontificia Univ Catolica Rio Grande do Sul, Porto Alegre, RS, Brazil | - |
hcfmusp.author.external | OLIVEIRA, Irismar Reis de:Univ Fed Bahia, Fac Med, Programa Posgrad Med & Saude, BR-41170290 Salvador, BA, Brazil | - |
hcfmusp.author.external | ROCHA, Fabio Lopes:Inst Previdencia Servidores Estado Minas Gerais, Postgrad Course, Belo Horizonte, MG, Brazil; Inst Previdencia Servidores Estado Minas Gerais, Psychiat Clin, Belo Horizonte, MG, Brazil | - |
hcfmusp.description.beginpage | 444 | - |
hcfmusp.description.endpage | 448 | - |
hcfmusp.description.issue | 5 | - |
hcfmusp.description.volume | 17 | - |
hcfmusp.origem | WOS | - |
hcfmusp.origem.id | 2-s2.0-84878450938 | - |
hcfmusp.origem.id | WOS:000319686800008 | - |
hcfmusp.publisher.city | THOUSAND OAKS | - |
hcfmusp.publisher.country | USA | - |
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dc.description.index | MEDLINE | - |
hcfmusp.remissive.sponsorship | Janssen | - |
hcfmusp.citation.scopus | 36 | - |
hcfmusp.scopus.lastupdate | 2024-04-12 | - |
Appears in Collections: | Artigos e Materiais de Revistas Científicas - HC/IPq |
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art_LOUZA_A_Multicenter_Open_Label_Trial_to_Evaluate_the_2013.PDF Restricted Access | publishedVersion (English) | 650.48 kB | Adobe PDF | View/Open Request a copy |
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