Drug-Induced Anaphylaxis

Imagem de Miniatura
Arquivos
art_AUN_DrugInduced_Anaphylaxis_2017.PDF (374.26 KB)
Citações na Scopus
22
Tipo de produção
article
Data de publicação
2017
DOI
Scopus
Web of Science
PubMed
Título da Revista
ISSN da Revista
Título do Volume
Editora
W B SAUNDERS CO-ELSEVIER INC
Autores
Citação
IMMUNOLOGY AND ALLERGY CLINICS OF NORTH AMERICA, v.37, n.4, p.629-0, 2017
Projetos de Pesquisa
Unidades Organizacionais
Fascículo
Resumo
Drugs are among the main triggers of anaphylaxis, but identification of the culprit drug is frequently difficult. To confirm diagnosis of the causative agent, medical records and clinical history are fundamental. There are a few in vitro tests available in clinical practice, such as serum-specific IgE and basophil activation test. Skin tests are often useful for the diagnosis, although drug challenge is indicated in patients with inconclusive clinical history or to provide safe alternatives. Treatment of anaphylaxis is standard and intramuscular epinephrine is the main agent to prevent morbidity and mortality. Rapid desensitization may be indicated in selected cases.
Palavras-chave
Anaphylaxis, Drug allergy, Adverse drug reactions, Hypersensitivity, Nonsteroidal anti-inflammatory drugs, Epinephrine
URI
https://observatorio.fm.usp.br/handle/OPI/24205
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Coleções
Artigos e Materiais de Revistas Científicas - FM/MCM
Artigos e Materiais de Revistas Científicas - HC/ICHC
Artigos e Materiais de Revistas Científicas - LIM/19
Artigos e Materiais de Revistas Científicas - LIM/60