Brazilian guidelines for the clinical management of paracoccidioidomycosis

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dc.contributor Sistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP
dc.contributor.author SHIKANAI-YASUDA, Maria Aparecida FMUSP-HC
MENDES, Rinaldo Poncio
COLOMBO, Arnaldo Lopes
QUEIROZ-TELLES, Flavio de
KONO, Adriana Satie Goncalves FMUSP-HC
PANIAGO, Anamaria M. M.
NATHAN, Andre FMUSP-HC
VALLE, Antonio Carlos Francisconi do
BAGAGLI, Eduardo
BENARD, Gil FMUSP-HC
FERREIRA, Marcelo Simao
TEIXEIRA, Marcus de Melo
SILVA-VERGARA, Mario Leon
PEREIRA, Ricardo Mendes
CAVALCANTE, Ricardo de Souza
HAHN, Rosane
DURLACHER, Rui Rafael
KHOURY, Zarifa
CAMARGO, Zoilo Pires de
MORETTI, Maria Luiza
MARTINEZ, Roberto
dc.date.issued 2017
dc.identifier.citation REVISTA DA SOCIEDADE BRASILEIRA DE MEDICINA TROPICAL, v.50, n.5, p.715-740, 2017
dc.identifier.issn 0037-8682
dc.identifier.uri http://observatorio.fm.usp.br/handle/OPI/24282
dc.description.abstract Paracoccidioidomycosis is a systemic fungal disease occurring in Latin America that is associated with rural environments and agricultural activities. However, the incidence and prevalence of paracoccidiodomycosis is underestimated because of the lack of compulsory notification. If paracoccidiodomycosis is not diagnosed and treated early and adequately, the endemic fungal infection could result in serious sequelae. While the Paracoccidioides brasiliensis (P. brasiliensis) complex has been known to be the causal agent of paracoccidiodomycosis, a new species, Paracoccidioides lutzii (P. lutzii), has been reported in Rondonia, where the disease has reached epidemic levels, and in the Central West and Para. Accurate diagnoses and availability of antigens that are reactive with the patients' sera remain significant challenges. Therefore, the present guidelines aims to update the first Brazilian consensus on paracoccidioidomycosis by providing evidence-based recommendations for bedside patient management. This consensus summarizes etiological, ecoepidemiological, molecular epidemiological, and immunopathological data, with emphasis on clinical, microbiological, and serological diagnosis and management of clinical forms and sequelae, as well as in patients with comorbidities and immunosuppression. The consensus also includes discussion of outpatient treatments, severe disease forms, disease prevalence among special populations and resource-poor settings, a brief review of prevention and control measures, current challenges and recommendations.
dc.description.sponsorship · Brazilian Society of Tropical Medicine and Hygiene
· Brazilian Society of Infectology and Sociedade Paulista de Infectologia
· Departamento de Molestias Infecciosas e Parasitarias da FMUSP
dc.language.iso eng
dc.publisher SOC BRASILEIRA MEDICINA TROPICAL
dc.relation.ispartof Revista da Sociedade Brasileira de Medicina Tropical
dc.rights openAccess
dc.subject Paracoccidioidomycosis; Guidelines; Clinical management; Diagnosis; Treatment follow-up
dc.subject.other human-immunodeficiency-virus; regulatory t-cells; pulmonary paracoccidioidomycosis; trimethoprim-sulfamethoxazole; follow-up; itraconazole; brasiliensis; lutzii; tests; immunosuppression
dc.title Brazilian guidelines for the clinical management of paracoccidioidomycosis
dc.type article
dc.rights.holder Copyright SOC BRASILEIRA MEDICINA TROPICAL
dc.description.group LIM/09
dc.description.group LIM/48
dc.description.group LIM/53
dc.identifier.doi 10.1590/0037-8682-0230-2017
dc.identifier.pmid 28746570
dc.type.category original article
dc.type.version publishedVersion
hcfmusp.author SHIKANAI-YASUDA, Maria Aparecida:FM:MIP
hcfmusp.author KONO, Adriana Satie Goncalves:HC:ICHC
hcfmusp.author NATHAN, Andre:HC:INCOR
hcfmusp.author BENARD, Gil:FM:MDT
hcfmusp.author.external · MENDES, Rinaldo Poncio:Univ Estadual Paulista, Fac Med Botucatu, Dept Doencas Tropicais & Diagnost Imagem, Botucatu, SP, Brazil
· COLOMBO, Arnaldo Lopes:Univ Fed Sao Paulo, Escola Paulista Med, Dept Med, Sao Paulo, SP, Brazil
· QUEIROZ-TELLES, Flavio de:Univ Fed Parana, Dept Saude Comunitaria, Curitiba, Parana, Brazil
· PANIAGO, Anamaria M. M.:Univ Fed Mato Grosso do Sul, Fac Med, Campo Grande, MS, Brazil
· VALLE, Antonio Carlos Francisconi do:Fundacao Oswaldo Cruz, Inst Pesquisa Clin Evandro Chagas, Rio De Janeiro, RJ, Brazil
· BAGAGLI, Eduardo:Univ Estadual Paulista, Inst Biociencias, Dept Microbiol & Imunol, Botucatu, SP, Brazil
· FERREIRA, Marcelo Simao:Univ Fed Uberlandia, Fac Med, Serv Infectol, Uberlandia, MG, Brazil
· TEIXEIRA, Marcus de Melo:No Arizona Univ, Translat Genom Res Inst, Flagstaff, AZ 86011 USA
· SILVA-VERGARA, Mario Leon:Univ Fed Triangulo Mineiro, Dept Clin Med, Fac Med, Uberaba, MG, Brazil
· PEREIRA, Ricardo Mendes:Univ Estadual Campinas, Dept Pediat, Fac Ciencias Med, Campinas, SP, Brazil
· CAVALCANTE, Ricardo de Souza:Univ Estadual Paulista, Fac Med Botucatu, Dept Doencas Tropicais & Diagnost Imagem, Botucatu, SP, Brazil
· HAHN, Rosane:Univ Fed Mato Grosso, Fac Ciencias Med, Nucleo Doencas Infecciosas & Tropicais, Cuiaba, MT, Brazil
· DURLACHER, Rui Rafael:Ctr Med Trop Rondonia, Porto Velho, RO, Brazil
· KHOURY, Zarifa:Secretaria Estado Saude Sao Paulo, Inst Infectol Emilio Ribas, Sao Paulo, SP, Brazil
· CAMARGO, Zoilo Pires de:Univ Fed Sao Paulo, Dept Microbiol & Imunol, Sao Paulo, SP, Brazil
· MORETTI, Maria Luiza:Univ Estadual Campinas, Dept Clin Med, Fac Ciencias Med, Campinas, SP, Brazil
· MARTINEZ, Roberto:Univ Sao Paulo, Fac Med Ribeirao Preto, Dept Clin Med, Ribeirao Preto, SP, Brazil
hcfmusp.origem.id WOS:000414732300025
hcfmusp.origem.id 2-s2.0-85032028722
hcfmusp.origem.id SCIELO:S0037-86822017000500715
hcfmusp.publisher.city BRASILIA
hcfmusp.publisher.country BRAZIL
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dc.description.index MEDLINE
hcfmusp.citation.scopus 50
hcfmusp.citation.wos 42
hcfmusp.affiliation.country Brasil
hcfmusp.affiliation.country Estados Unidos


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