Modified Pfeffer Questionnaire for Functional Assessment in Parkinson Disease

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dc.contributor Sistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP
dc.contributor.author ALMEIDA, Kelson James FMUSP-HC
MACEDO, Livio Pereira de
LOPES, Janine Lemos de Melo Lobo Jofili
BOR-SENG-SHU, Edson FMUSP-HC
CAMPOS-SOUSA, Raimundo Nonato
BARBOSA, Egberto Reis FMUSP-HC
dc.date.issued 2017
dc.identifier.citation JOURNAL OF GERIATRIC PSYCHIATRY AND NEUROLOGY, v.30, n.5, p.261-266, 2017
dc.identifier.issn 0891-9887
dc.identifier.uri http://observatorio.fm.usp.br/handle/OPI/25756
dc.description.abstract Introduction: It was proposed to modify the Pfeffer questionnaire (PQ) for functional assessment in patients with Parkinson disease (PD). Aim: To determine the cutoff score for diagnosis of functional impairment in patients with PD by modified PQ (mPQ). Methods: A total of 110 patients with PD were enrolled into the study, and a neuropsychological test battery was performed to assess their cognitive status. Regarding functional assessment, the mPQ has been applied, and their results were compared to the functional assessment by Informant Questionnaire on Cognitive Decline in the Elderly adapted for use in Brazil (IQCODE-BR). The statistical analysis was accomplished through receiver operating characteristic (ROC) curve with evaluation of the area under the curve, sensitivity, and specificity of the new cutoff point. Results: Eighty-nine patients with PD were evaluated with a mean age of 63.69 +/- 9.14 years. Cognitive status categorization was 28.10% as normal, 44.94% as mild cognitive impairment, and 26.96% of patients as dementia associated with PD. The average score on PQ was 3.49 +/- 4.79 and on the mPQ 2.56 +/- 3.49. In IQCODE-BR, the average score was 6.75 +/- 32.72. The ROC curve for the new cutoff point presented 47.4% sensitivity, 88.10% specificity, and 0.757 of area under the curve, with a standard deviation of 0.055 (95% confidence interval: 0.650-0.864). Conclusion: 3.5 is proposed as the cutoff point to define functional impairment in patients with PD by mPQ.
dc.language.iso eng
dc.publisher SAGE PUBLICATIONS INC
dc.relation.ispartof Journal of Geriatric Psychiatry and Neurology
dc.rights restrictedAccess
dc.subject Parkinson disease; questionnaires; cognition
dc.subject.other mild cognitive impairment; society task-force; informant-questionnaire; diagnostic-criteria; elderly iqcode; dementia; decline; depression; prognosis; cohort
dc.title Modified Pfeffer Questionnaire for Functional Assessment in Parkinson Disease
dc.type article
dc.rights.holder Copyright SAGE PUBLICATIONS INC
dc.description.group LIM/26
dc.description.group LIM/45
dc.identifier.doi 10.1177/0891988717720298
dc.identifier.pmid 28747137
dc.type.category original article
dc.type.version publishedVersion
hcfmusp.author ALMEIDA, Kelson James:FM:
hcfmusp.author BOR-SENG-SHU, Edson:HC:ICHC
hcfmusp.author BARBOSA, Egberto Reis:HC:ICHC
hcfmusp.author.external · MACEDO, Livio Pereira de:Facid Devry Univ Med, Dept Neurol, Canada St 2070, Teresina, Piaui, Brazil
· LOPES, Janine Lemos de Melo Lobo Jofili:Univ Fed Piaui, Dept Neurol, Teresina, Piaui, Brazil
· CAMPOS-SOUSA, Raimundo Nonato:Univ Fed Piaui, Dept Neurol, Teresina, Piaui, Brazil
hcfmusp.origem.id 2-s2.0-85029640661
hcfmusp.origem.id WOS:000417081500003
hcfmusp.publisher.city THOUSAND OAKS
hcfmusp.publisher.country USA
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dc.description.index MEDLINE
dc.identifier.eissn 1552-5708
hcfmusp.citation.scopus 1
hcfmusp.citation.wos 0
hcfmusp.affiliation.country Brasil


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