Cardiac Remodeling Patterns in Severe Obesity According to Arterial Hypertension Grade

Imagem de Miniatura
Arquivos
art_CLEVA_Cardiac_Remodeling_Patterns_in_Severe_Obesity_According_to_2018.PDF (2.7 MB)
Citações na Scopus
7
Tipo de produção
article
Data de publicação
2018
Editora
SPRINGER
DOI
Indexadores
Scopus
Web of Science
PubMed
Título da Revista
ISSN da Revista
Título do Volume
Autores
COSTA, Fabio de Oliveira
Autor de Grupo de pesquisa
Editores
Coordenadores
Organizadores
Citação
OBESITY SURGERY, v.28, n.4, p.1047-1054, 2018
Projetos de Pesquisa
Unidades Organizacionais
Fascículo
Resumo
The purpose of this study is to correlate the left ventricular hypertrophy (LVH) patterns according to severe obesity and arterial hypertension (AHT) grades. A cross-sectional prospective study was conducted in 379 patients with severe obesity. Obesity was classified according to the BMI in the following: morbidly obese (MO; 40 < BMI < 50 kg/m(2)) and super obese (SO; BMI > 50 kg/m(2)). The AHT was classified into classes 1 and 2 according to American Heart Association. The presence of LVH and the pattern of cardiac remodeling were determined by transthoracic echocardiography. LVH was present in 58.6% of patients. Obesity and AHT had additive effects in LVH prevalence. LVH was found in 32.9 and 46.7% of MO with AHT grades 1 and 2, respectively. LVH was diagnosed in 39.1% in SO with AHT grade 1 and in 50% of AHT grade 2. Patients with AHT presented a significantly higher risk of developing LVH (OR 1.97; p = 0.003). Hypertension grade was also a determinant variable in the development of LVH. Patients with AHT 2 had 4.31-fold greater risk (p < 0.001) when compared to normotensive patients. BMI was only considered an independent risk factor for LVH in patients with BMI greater than 47.17 kg/m(2) (OR 1.62; p = 0.023). AHT is a stronger predictive factor of LVH than obesity grade.
Palavras-chave
Severe obesity, Hypertension, Left ventricular hypertrophy
URI
https://observatorio.fm.usp.br/handle/OPI/26321
Referências
  1. ALPERT MA, 1995, AM J CARDIOL, V76, P1194, DOI 10.1016/S0002-9149(99)80338-5
  2. Aurigemma GP, 2002, AM HEART J, V143, P546, DOI 10.1067/mhj.2002.119764
  3. Avelar E, 2007, HYPERTENSION, V49, P34, DOI 10.1161/01.HYP.0000251711.92482.14
  4. Beinart R, 2004, J AM COLL CARDIOL, V44, P327, DOI 10.1016/j.jacc.2004.03.062
  5. Bombelli M, 2009, J HYPERTENS, V27, P2458, DOI 10.1097/HJH.0b013e328330b845
  6. Bray GA, 2004, J CLIN ENDOCR METAB, V89, P2583, DOI 10.1210/jc.2004-0535
  7. Calle EE, 1993, NEW ENGL J MED, V41, P1097
  8. CAMPUS S, 1987, J CLIN HYPERTENS, V3, P79
  9. Chobanian AV, 2003, HYPERTENSION, V42, P1206, DOI 10.1161/01.HYP.0000107251.49515.c2
  10. Centers for Disease Control and Prevention, OV OB US OB TRENDS
  11. de Simone G, 2001, HYPERTENSION, V38, P13, DOI 10.1161/01.HYP.38.1.13
  12. DELAMAZA MP, 1994, INT J OBESITY, V18, P193
  13. DESIMONE G, 1994, HYPERTENSION, V23, P600, DOI 10.1161/01.HYP.23.5.600
  14. Ford ES, 2008, J CLIN ENDOCR METAB, V93, pS1, DOI 10.1210/jc.2008-1356
  15. FROHLICH ED, 1989, J MOL CELL CARDIOL, V21, P3, DOI 10.1016/0022-2828(89)90767-0
  16. GANAU A, 1992, J AM COLL CARDIOL, V19, P1550, DOI 10.1016/0735-1097(92)90617-V
  17. GANAU A, 1990, CIRCULATION, V81, P25, DOI 10.1161/01.CIR.81.1.25
  18. GANAU A, 1991, J HYPERTENS, V9, pS150
  19. Gerdts E, 2007, HYPERTENSION, V49, P311, DOI 10.1161/01.HYP.0000254322.96189.85
  20. Giampaoli S, 2009, PREV MED, V48, P525, DOI 10.1016/j.ypmed.2009.03.017
  21. GROSSMAN W, 1975, J CLIN INVEST, V56, P56, DOI 10.1172/JCI108079
  22. HAMMOND IW, 1986, J AM COLL CARDIOL, V7, P639, DOI 10.1016/S0735-1097(86)80476-4
  23. Kenchaiah S, 2002, NEW ENGL J MED, V347, P305, DOI 10.1056/NEJMoa020245
  24. Kotchen TA, 2010, AM J HYPERTENS, V23, P1170, DOI 10.1038/ajh.2010.172
  25. KRONMAL RA, 1993, J ROY STAT SOC A STA, V156, P379, DOI 10.2307/2983064
  26. Lang RM, 2005, J AM SOC ECHOCARDIOG, V18, P1440, DOI 10.1016/j.echo.2005.10.005
  27. LAUER MS, 1991, JAMA-J AM MED ASSOC, V266, P231, DOI 10.1001/jama.266.2.231
  28. LAUER MS, 1992, J AM COLL CARDIOL, V19, P130, DOI 10.1016/0735-1097(92)90063-S
  29. Le Jemtel TH, 2017, CURR HYPERTENS REP, V19, DOI 10.1007/s11906-017-0767-5
  30. LEVY D, 1990, NEW ENGL J MED, V322, P1561, DOI 10.1056/NEJM199005313222203
  31. LEVY D, 1989, ANN INTERN MED, V110, P101, DOI 10.7326/0003-4819-110-2-101
  32. Li XR, 2004, CIRCULATION, V110, P3488, DOI 10.1161/01.CIR.0000149713.48317.27
  33. Melenovsky V, 2007, J AM COLL CARDIOL, V49, P198, DOI 10.1016/j.jacc.2006.08.050
  34. MESSERLI FH, 1983, ANN INTERN MED, V99, P757, DOI 10.7326/0003-4819-99-6-757
  35. MESSERLI FH, 1982, LANCET, V1, P1165
  36. Peterson LR, 2004, J AM COLL CARDIOL, V43, P1399, DOI 10.1016/j.jacc.2003.10.062
  37. Sturm R, 2007, PUBLIC HEALTH, V121, P492, DOI 10.1016/j.puhe.2007.01.006
  38. Verdecchia P, 1998, CIRCULATION, V97, P48
  39. Wilson PWF, 2002, ARCH INTERN MED, V162, P1867, DOI 10.1001/archinte.162.16.1867
  40. Wong CY, 2004, CIRCULATION, V110, P3081, DOI 10.1161/01.CIR.0000147184.13872.0F

Coleções
Artigos e Materiais de Revistas Científicas - FM/MGT
Artigos e Materiais de Revistas Científicas - HC/ICHC
Artigos e Materiais de Revistas Científicas - LIM/35
Artigos e Materiais de Revistas Científicas - ODS/03