T-piece versus self-inflating bag ventilation in preterm neonates at birth

Carregando...
Imagem de Miniatura
Citações na Scopus
44
Tipo de produção
article
Data de publicação
2018
Título da Revista
ISSN da Revista
Título do Volume
Editora
BMJ PUBLISHING GROUP
Autores
GUINSBURG, Ruth
ALMEIDA, Maria Fernanda Branco de
CASTRO, Junia Sampel de
GONCALVES-FERRI, Walusa Assad
MARQUES, Patricia Franco
CALDAS, Jamil Pedro Siqueira
RUGOLO, Ligia Maria Suppo de Souza
ALMEIDA, Joao Henrique Carvalho Leme de
LUZ, Jorge Hecker
Citação
ARCHIVES OF DISEASE IN CHILDHOOD-FETAL AND NEONATAL EDITION, v.103, n.1, p.F49-F54, 2018
Projetos de Pesquisa
Unidades Organizacionais
Fascículo
Resumo
Objective To verify whether the use of the T-piece resuscitator compared with the self-inflating bag in preterm infants ventilated at birth modifies survival to hospital discharge without major morbidities. Design Pragmatic prospective cohort study. Setting 20 Brazilian university hospitals of Brazilian Network on Neonatal Research. Patients were 1962 inborn infants in 2014-2015 ventilated at birth with 23-33' weeks gestation and birth weight 400-1499 g without malformations. Patients transferred until the 27th day after birth were excluded. Interventions Positive pressure ventilation at birth with T-piece resuscitator or self-inflating bag without positive end expiratory pressure valve. Intervention with ventilation followed the Brazilian Society of Pediatrics guidelines. The choice of the equipment was at the neonatologist's discretion in each delivery. The main outcome measures were survival to hospital discharge without bronchopulmonary dysplasia, severe peri-intraventricular haemorrhage and periventricular leucomalada. Logistic regression adjusted for confounding variables was applied for main outcome. Results 1456 (74%) were only ventilated with T-piece resuscitator and 506 (26%) with the self-inflating bag. The characteristics of those ventilated with T-Piece resuscitator versus self-inflating bag were birth weight 969 +/- 277 vs 941 +/- 279 g, gestational age 28.2 +/- 2.5 vs 27.8 +/- 2.7 weeks and survival to hospital discharge without major morbidities 47% vs 35%, Logistic regression adjusted for maternal characteristics, obstetric and neonatal morbidities showed that the T-piece resuscitator increased the chance of survival to hospital discharge without major morbidities (OR=1.38; 95% Cl 1.06 to 1.80; Hosmer-Lemeshow goodness of fit: 0.695). Conclusion This study is the first that highlights the effectiveness of T-piece resuscitator ventilation in improving relevant outcomes in preterm neonates.
Palavras-chave
Referências
  1. Azevedo Bittencourt SD, 2014, CAD SAUDE PUBLICA S1, pS1
  2. Braima O, 2008, Ir Med J, V101, P142
  3. Dawson JA, 2011, J PEDIATR-US, V158, P912, DOI 10.1016/j.jpeds.2010.12.003
  4. DEVRIES LS, 1992, BEHAV BRAIN RES, V49, P1, DOI 10.1016/S0166-4328(05)80189-5
  5. Fernandez R, 2014, ARCH ARGENT PEDIATR, V112, P405, DOI [10.5546/aap.2014.405, 10.1590/S0325-00752014000500004]
  6. Guinsburg R, 2012, CURSO REANIMACAO PRE
  7. Guinsburg R, 2016, J MATERN-FETAL NEO M, V29, P1005, DOI 10.3109/14767058.2015.1031740
  8. Hawkes CP, 2012, RESUSCITATION, V83, P797, DOI 10.1016/j.resuscitation.2011.12.020
  9. Hooper SB, 2016, ARCH DIS CHILD-FETAL, V101, pF266, DOI 10.1136/archdischild-2013-305704
  10. Hooper SB, 2013, SEMIN FETAL NEONAT M, V18, P336, DOI 10.1016/j.siny.2013.08.011
  11. Horbar JD, 2012, PEDIATRICS, V129, P1019, DOI 10.1542/peds.2011-3028
  12. Iriondo M, 2009, ACTA PAEDIATR, V98, P786, DOI 10.1111/j.1651-2227.2009.01233.x
  13. Jobe Alan H., 2001, American Journal of Respiratory and Critical Care Medicine, V163, P1723
  14. Kusuda S, 2012, PEDIATR RES, V72, P531, DOI 10.1038/pr.2012.114
  15. Mann C, 2012, RESUSCITATION, V83, P607, DOI 10.1016/j.resuscitation.2012.01.002
  16. Olsen IE, 2010, PEDIATRICS, V125, pE214, DOI 10.1542/peds.2009-0913
  17. PAPILE LA, 1978, J PEDIATR-US, V92, P529, DOI 10.1016/S0022-3476(78)80282-0
  18. Perlman JM, 2015, CIRCULATION, V132, pS204, DOI 10.1161/CIR.0000000000000276
  19. Richardosn DK, 2001, J PEDIATR-US, V138, P92, DOI 10.1067/mpd.2001.109608
  20. Roehr CC, 2010, EUR J MED RES, V15, P493, DOI 10.1186/2047-783X-15-11-493
  21. Ruegger C, 2012, BMC PEDIATR, V12, DOI 10.1186/1471-2431-12-17
  22. Saude BMda, 2017, EST VIT
  23. Stoll BJ, 2010, PEDIATRICS, V126, P443, DOI 10.1542/peds.2009-2959
  24. Szyld E, 2014, J PEDIATR-US, V165, P234, DOI 10.1016/j.jpeds.2014.02.035
  25. Thakur A, 2015, RESUSCITATION, V90, P21, DOI 10.1016/j.resuscitation.2015.01.021
  26. Tyson J, 2015, AM J PERINAT, V32, P1095, DOI 10.1055/s-0035-1562927
  27. Watson SI, 2016, ARCH DIS CHILD-FETAL, V101, pF195, DOI 10.1136/archdischild-2015-309435
  28. World Health Organization, 1997, THERM PROT NEWB PRAC