Six- minute walk test (6MWT) in children and teenages with chronic kidney disease: tolerance, reproducibility and comparison with normal reference values

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dc.contributor Sistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP KOCH, Vera FMUSP-HC
dc.identifier.citation PEDIATRIC NEPHROLOGY, v.28, n.8, p.1365-1365, 2013
dc.identifier.issn 0931-041X
dc.description.abstract Objective: To evaluate exercise tolerance using the six-minute walk test (6MWT) in children and adolescents with stage 5 chronic kidney disease (CKD, to assess the reproducibility of the 6MWT and compare the performance of these children with reference values. Methods: Children and adolescents aged 6 to 16 years with stage 5 CKD were evaluated prospectively using 6MWT, according to the American Thoracic Society methodology. Measurement of Heart rate (HR), respiratory rate (RR), pulse oxygen saturation (SpO2), blood pressure (BP) and dyspnea scale (Borg) at rest (pre) and posttest (post) was performed. The test with the larger walked distance was considered for analysis. Reproducibility was evaluated by t-test and the Bland-Altman methods. Brazilian population reference values were used for comparison with normal children. Results: We studied 38 children and adolescents (14F:24M), 4 on peritoneal dialysis, 12 hemodialysis and 22 post renal transplantation with a mean age of 11.3 ± 2.9 years, mean weight of 32.3 ± 11.7 kg, mean height of 131 ± 17cm and mean BMI of 18.3 ± 3.1 kg/m2. There were no adverse events observed during or after the tests. The 6MWT was found to be reproducible, second walk walked distances were greater than first walk ones (p <0.001). Children with CKD performed significantly poorer (548.9 ± 71.4 m) than reference values of children with similar height (576.46 ±39.76 m) (p <0.001). HR, SpO2, systolic BP (pre), diastolic BP were significantly higherin children with CKD. Conclusion: The 6MWT proved to be safe, reproducible and well tolerated. A learning effect was observed between the first and second test. CKD patients performed significantly poorer than reference values.
dc.language.iso eng
dc.publisher SPRINGER
dc.relation.ispartof Pediatric Nephrology
dc.rights restrictedAccess
dc.title Six- minute walk test (6MWT) in children and teenages with chronic kidney disease: tolerance, reproducibility and comparison with normal reference values
dc.type conferenceObject
dc.rights.holder Copyright SPRINGER
dc.description.conferencedate AUGUST 30-SEPTEMBER 3, 2013
dc.description.conferencelocal Shangai, CHINA
dc.description.conferencename 16TH TRI-ANNUAL IPNA CONGRESS LIM/21 LIM/36
dc.type.category meeting abstract
dc.type.version publishedVersion KOCH, Vera:HC:ICR CUNHA, Maristela:HC:ICR FERRARO, Alexandre:FM:MPE JULIANI, Regina:HC:ICR · WATANABE, Flavia T.:Nstituto Crianca HCFMUSP, Pediat, Sao Paulo, Brazil WOS:000321387201056 NEW YORK USA
dc.description.index MEDLINE
hcfmusp.citation.wos 0 Brasil

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