Obsessive-compulsive symptoms in children with first degree relatives diagnosed with obsessive-compulsive disorder

Carregando...
Imagem de Miniatura
Citações na Scopus
13
Tipo de produção
article
Data de publicação
2018
Título da Revista
ISSN da Revista
Título do Volume
Editora
ASSOC BRASILEIRA PSIQUIATRIA
Citação
REVISTA BRASILEIRA DE PSIQUIATRIA, v.40, n.4, p.388-393, 2018
Projetos de Pesquisa
Unidades Organizacionais
Fascículo
Resumo
Objective: A first-degree relative affected by obsessive-compulsive disorder (OCD) and obsessive-compulsive symptoms (OCS) in childhood is an important risk factor for developing the disorder in adulthood. The relationship between a family history of OCD and the presence of OCS and its correlates in childhood is not well established. Methods: A total of 66 children whose parents or siblings have been diagnosed with OCD were assessed for the presence of OCS and clinical correlates. Results: Three children (4.5%) were reported to have received an OCD diagnosis and another 26 (39.4%) were identified as having OCS. Children with OCS had higher rates of coercive behavior and came from families with lower socioeconomic status. Contamination/cleaning dimension symptoms in the proband were associated with OCS in the assessed children. Conclusion: OCS are frequent among family members of individuals with OCD and are associated with socioeconomic status, coercive behaviors and proband contamination/cleaning symptoms. Future longitudinal studies should test the risk of developing OCD in association with these characteristics.
Palavras-chave
Obsessive-compulsive symptoms, children, familial OCD, coercive behaviors
Referências
  1. Black DW, 2003, ACTA PSYCHIAT SCAND, V107, P305, DOI 10.1034/j.1600-0447.2003.02182.x
  2. Budman CL, 1998, J CLIN PSYCHIAT, V59, P576, DOI 10.4088/JCP.v59n1103
  3. CALVOCORESSI L, 1995, AM J PSYCHIAT, V152, P441
  4. Calvocoressi L, 1999, J NERV MENT DIS, V187, P636, DOI 10.1097/00005053-199910000-00008
  5. Chacon P, 2007, AM J MED GENET B, V144B, P551, DOI 10.1002/ajmg.b.30457
  6. de Mathis MA, 2013, EUR NEUROPSYCHOPHARM, V23, P594, DOI 10.1016/j.euroneuro.2012.08.006
  7. Degnan KA, 2010, J CHILD PSYCHOL PSYC, V51, P497, DOI 10.1111/j.1469-7610.2010.02228.x
  8. Evans DW, 1999, CHILD PSYCHIAT HUM D, V29, P261, DOI 10.1023/A:1021392931450
  9. FAVA M, 1995, PSYCHIAT RES, V56, P205, DOI 10.1016/0165-1781(95)02577-J
  10. FLAMENT MF, 1988, J AM ACAD CHILD PSY, V27, P764, DOI 10.1097/00004583-198811000-00018
  11. Fullana MA, 2009, AM J PSYCHIAT, V166, P329, DOI [10.1176/appi.ajp.2008.08071006, 10.1176/appi.ajp.2008/08071006]
  12. Geller DA, 2001, J NERV MENT DIS, V189, P471, DOI 10.1097/00005053-200107000-00009
  13. Grover S, 2011, TURK PSIKIYATR DERG, V22, P239
  14. Hanna GL, 2005, BIOL PSYCHIAT, V57, P895, DOI 10.1016/j.biopsych.2004.12.022
  15. Hanna GL, 2005, AM J MED GENET B, V134B, P13, DOI 10.1002/ajmg.30138
  16. Hasler G, 2007, BIOL PSYCHIAT, V61, P617, DOI 10.1016/j.biopsych.2006.05.040
  17. Iervolino AC, 2011, ARCH GEN PSYCHIAT, V68, P637, DOI 10.1001/archgenpsychiatry.2011.54
  18. Katerberg H, 2010, BEHAV GENET, V40, P505, DOI 10.1007/s10519-010-9339-z
  19. Krebs G, 2013, J CHILD PSYCHOL PSYC, V54, P313, DOI 10.1111/j.1469-7610.2012.02605.x
  20. Lebowitz ER, 2012, EXPERT REV NEUROTHER, V12, P229, DOI [10.1586/ern.11.200, 10.1586/ERN.11.200]
  21. Lebowitz ER, 2011, DEPRESS ANXIETY, V28, P899, DOI 10.1002/da.20858
  22. Leckman JF, 2003, AM J MED GENET B, V116B, P60, DOI 10.1002/ajmg.b.10001
  23. Mataix-Cols D, 2013, JAMA PSYCHIAT, V70, P709, DOI 10.1001/jamapsychiatry.2013.3
  24. Miguel EC, 2009, REV BRAS PSIQUIATR, V31, P85, DOI 10.1590/S1516-44462009000200001
  25. Miguel EC, 2008, REV BRAS PSIQUIATR, V30, P185, DOI 10.1590/S1516-44462008000300003
  26. Painuly Nitesh Prakash, 2011, Ind Psychiatry J, V20, P115, DOI 10.4103/0972-6748.102501
  27. Painuly NP, 2011, PSYCHIAT CLIN NEUROS, V65, P165, DOI 10.1111/j.1440-1819.2010.02177.x
  28. PAULS DL, 1995, AM J PSYCHIAT, V152, P76
  29. Rohde P, 1997, AM J PSYCHIAT, V154, P1593, DOI 10.1176/ajp.154.11.1593
  30. Rosario-Campos MC, 2006, MOL PSYCHIATR, V11, P495, DOI 10.1038/sj.mp.4001798
  31. Ruscio AM, 2010, MOL PSYCHIATR, V15, P53, DOI 10.1038/mp.2008.94
  32. SANSON AV, 1994, MERRILL PALMER QUART, V40, P233
  33. Sidman M., 1989, COERCION ITS FALLOUT
  34. Storch EA, 2012, J AM ACAD CHILD PSY, V51, P582, DOI 10.1016/j.jaac.2012.02.016
  35. VALLENIBASILE LA, 1994, J AM ACAD CHILD PSY, V33, P782, DOI 10.1097/00004583-199407000-00002
  36. van Grootheest DS, 2005, TWIN RES HUM GENET, V8, P450, DOI 10.1375/twin.8.5.450
  37. Wilcox HC, 2008, J AFFECT DISORDERS, V111, P31, DOI 10.1016/j.jad.2008.01.025