Alternative treatment to surgery for rectal cancer

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Arquivos
art_HABR-GAMA_Alternative_treatment_to_surgery_for_rectal_cancer_2018.PDF (882.09 KB)
Citações na Scopus
Tipo de produção
article
Data de publicação
2018
DOI
Web of Science
Título da Revista
ISSN da Revista
Título do Volume
Editora
AME PUBL CO
Autores
FERNANDEZ, Laura Melina
JULIAO, Guilherme Pagin Sao
VAILATI, Bruna Borba
Citação
ANNALS OF LAPAROSCOPIC AND ENDOSCOPIC SURGERY, v.3, article ID UNSP 50, 9p, 2018
Projetos de Pesquisa
Unidades Organizacionais
Fascículo
Resumo
The traditional concept of rectal cancer management has changed significantly over the last few years. Although surgical resection remains central the treatment of distal rectal cancer by proctectomy and total mesorectal excision (TME), there has been increased interest in organ preservation strategies. Neoadjuvant chemoradiation (nCRT) may result in significant tumor regression and complete pathological response may be observed in up to 42% of patients. In order to avoid the morbidity, mortality and functional consequences of major surgery, selected patients with clinical and radiological evidence of significant tumor regression after nCRT have been managed non-operatively with strict follow-up (Watch & Wait Strategy-WW) with acceptable outcomes and minimal functional consequences. In addition, close surveillance may allow early detection of local recurrences and salvage alternatives with no oncological compromise.
Palavras-chave
Rectal cancer, organ-preservation, Watch & Wait
URI
https://observatorio.fm.usp.br/handle/OPI/29934
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Coleções
Artigos e Materiais de Revistas Científicas - FM/MGT