Guidelines of the Brazilian Society of Rheumatology for the treatment of systemic autoimmune myopathies

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dc.contributor Sistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP SOUZA, Fernando Henrique Carlos de FMUSP-HC
ARAUJO, Daniel Brito de
VILELA, Veronica Silva
BEZERRA, Mailze Campos
SIMOES, Ricardo Santos FMUSP-HC
BERNARDO, Wanderley Marques FMUSP-HC
CUNHA, Bernardo Matos da
SHINJO, Samuel Katsuyuki FMUSP-HC 2019
dc.identifier.citation ADVANCES IN RHEUMATOLOGY, v.59, article ID 6, 12p, 2019
dc.identifier.issn 2523-3106
dc.description.abstract Background: Recommendations of the Myopathy Committee of the Brazilian Society of Rheumatology for the management and therapy of systemic autoimmune myopathies (SAM). Main body: The review of the literature was done in the search for the Medline (PubMed), Embase and Cochrane databases including studies published until June 2018. The Prisma was used for the systematic review and the articles were evaluated according to the levels of Oxford evidence. Ten recommendations were developed addressing the management and therapy of systemic autoimmune myopathies. Conclusions: Robust data to guide the therapeutic process are scarce. Although not proven effective in controlled clinical trials, glucocorticoid represents first-line drugs in the treatment of SAM. Intravenous immunoglobulin is considered in induction for refractory cases of SAM or when immunosuppressive drugs are contra-indicated. Consideration should be given to the early introduction of immunosuppressive drugs. There is no specific period determined for the suspension of glucocorticoid and immunosuppressive drugs when individually evaluating patients with SAM. A key component for treatment in an early rehabilitation program is the inclusion of strength-building and aerobic exercises, in addition to a rigorous evaluation of these activities for remission of disease and the education of the patient and his/her caregivers.
dc.description.sponsorship · Brazilian Society of Rheumatology
dc.language.iso eng
dc.publisher BMC
dc.relation.ispartof Advances in Rheumatology
dc.rights restrictedAccess
dc.subject Dermatomyositis; Guidelines; Polymyositis; Systemic autoimmune myopathies; Treatment
dc.subject.other pneumocystis-carinii-pneumonia; interstitial lung-disease; idiopathic inflammatory myopathies; cell activating factor; term-follow-up; refractory polymyositis; juvenile dermatomyositis; mycophenolate-mofetil; myositis patients; cyclosporine-a
dc.title Guidelines of the Brazilian Society of Rheumatology for the treatment of systemic autoimmune myopathies
dc.type article
dc.rights.holder Copyright BMC LIM/17
dc.identifier.doi 10.1186/s42358-019-0048-x
dc.identifier.pmid 30670084
dc.type.category original article
dc.type.version publishedVersion SOUZA, Fernando Henrique Carlos de:HC:ICHC SIMOES, Ricardo Santos:HC:ICHC BERNARDO, Wanderley Marques:FM: MIOSSI, Renata:HC:ICHC SHINJO, Samuel Katsuyuki:FM:MCM · ARAUJO, Daniel Brito de:UFP, Pelotas, RS, Brazil
· VILELA, Veronica Silva:Univ Estado Rio De Janeiro, Rio De Janeiro, RJ, Brazil
· BEZERRA, Mailze Campos:HGF, Fortaleza, Ceara, Brazil
· CUNHA, Bernardo Matos da:Rede Sarah Hosp Reabilitacao, Brasilia, DF, Brazil WOS:000457521000003 2-s2.0-85060375842 SCIELO:S2523-31062019000100301 LONDON ENGLAND
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