Predictors of surgical complications of nephrectomy for urolithiasis

Carregando...
Imagem de Miniatura
Citações na Scopus
9
Tipo de produção
article
Data de publicação
2019
Título da Revista
ISSN da Revista
Título do Volume
Editora
BRAZILIAN SOC UROL
Citação
INTERNATIONAL BRAZ J UROL, v.45, n.1, p.100-107, 2019
Projetos de Pesquisa
Unidades Organizacionais
Fascículo
Resumo
Objectives: Nephrectomy due to stone disease may be a challenging procedure owing to the presence of significant inflammation and infection, involving high complication rate. The objective of our study was to identify predictors for complications of nephrectomy for urolithiasis. Patients and Methods: A retrospective review of 149 consecutive patients > 18y submitted to simple nephrectomy for urolithiasis from January 2006 to July 2012 was performed. Clinical data, computed tomography findings and pathology report were analyzed. Postoperative complications were categorized based on Clavien - Dindo classification. Logistic multivariate regression models assessed the predictors for surgical complications of nephrectomy for urolithiasis. Results: Eighty-three (55.7%) patients were submitted to laparoscopic nephrectomy and 66 (44.2%) to open procedure. Conversion to open surgery was necessary in 19.2% (16 / 83). On univariable analysis, higher preoperative chronic kidney stage (p = 0.02), Charlson comorbidity index >= 2 (p = 0.04), higher ASA score (p = 0.001), urgency due to sepsis (p = 0.01), kidney size >= 12 cm (p = 0.006), renal and perirenal abscess (p = 0.004 and 0.002 respectively) and visceral adhesion (p = 0.04) were associated with Clavien - Dindo score > 1. On multivariate analysis, higher ASA score (p = 0.01), urgency due to sepsis (p = 0.03), kidney size >= 12 cm (p = 0.04) and preoperative abscess (p = 0.04) remained significantly associated with complications. End - stage renal disease with dialysis was needed post - operatively in 3.4% (5 / 144) of patients. Conclusions: We identified that higher ASA score, urgency due to sepsis, kidney size >= 12 cm and preoperative abscess were associated with Clavien - Dindo score > 1.
Palavras-chave
Nephrectomy, Urolithiasis, Postoperative Complications
Referências
  1. Angerri O, 2016, J ENDOUROL, V30, P1095, DOI 10.1089/end.2016.0281
  2. CHARLSON ME, 1987, J CHRON DIS, V40, P373, DOI 10.1016/0021-9681(87)90171-8
  3. Choi YS, 2014, INT UROL NEPHROL, V46, P681, DOI 10.1007/s11255-013-0534-8
  4. Dindo D, 2004, ANN SURG, V240, P205, DOI 10.1097/01.sla.0000133083.54934.ae
  5. Duarte RJ, 2008, J ENDOUROL, V22, P681, DOI 10.1089/end.2007.0291
  6. Gill IS, 1998, UROLOGY, V52, P566, DOI 10.1016/S0090-4295(98)00314-8
  7. Gupta NP, 2008, J ENDOUROL, V22, P693, DOI 10.1089/end.2007.0267
  8. Huang WC, 2006, LANCET ONCOL, V7, P735, DOI 10.1016/S1470-2045(06)70803-8
  9. Keeley FX, 1998, BRIT J UROL, V82, P615
  10. Levey AS, 1999, ANN INTERN MED, V130, P461, DOI 10.7326/0003-4819-130-6-199903160-00002
  11. Manohar T, 2007, J ENDOUROL, V21, P1323, DOI 10.1089/end.2007.9883
  12. Mao SH, 2012, J ENDOUROL, V26, P1356, DOI 10.1089/end.2012.0080
  13. Matin SF, 2003, J UROLOGY, V170, P1115, DOI 10.1097/01.ju.0000086091.64755.ac
  14. Pearle MS, 2014, J UROLOGY, V192, P316, DOI 10.1016/j.juro.2014.05.006
  15. Permpongkosol S, 2007, J UROLOGY, V177, P580, DOI 10.1016/j.juro.2006.09.031
  16. Sankar A, 2014, BRIT J ANAESTH, V113, P424, DOI 10.1093/bja/aeu100
  17. Shoag J, 2015, ADV CHRONIC KIDNEY D, V22, P273, DOI 10.1053/j.ackd.2015.04.004
  18. Stephenson AJ, 2004, J UROLOGY, V171, P130, DOI 10.1097/01.ju.0000101281.04634.13
  19. Tepeler A, 2012, UROL RES, V40, P559, DOI 10.1007/s00240-012-0466-2
  20. Zelhof B, 2016, BJU INT, V117, P138, DOI 10.1111/bju.13141