An innovative laparoscopic and endoscopic technique in an animal model: combined gastric full-thickness tumor resection
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Citações na Scopus
Tipo de produção
article
Data de publicação
2019
Título da Revista
ISSN da Revista
Título do Volume
Editora
GEORG THIEME VERLAG KG
Citação
ENDOSCOPY INTERNATIONAL OPEN, v.7, n.4, p.E440-E445, 2019
Resumo
Background and study aims The combination of endoscopy with laparoscopy for full-thickness gastric resection has received much attention. The advantage in using it is removak of the target lesion without resection of excessive normal tissue. The technique could prevent deformed scars, particularly at the cardia and in the prepyloric arca. The aim of this protocol was to evaluate a new combined operation for full-thickness resection of the gastric wall. Materials and methods Gastric subepithelial lesions in multiple topographic locations of the stomach were simulated in seven live pigs. Full-thickness gastric resection was undertaken and after assessment of the outcome, the animals were euthanized. The primary endpoint was accomplishment of the procedure following all steps in the new technique, in various gastric locations. The secondary endpoints were duration of the procedure, quality of specimen margins, and complications. Results Resections were successful, complete, and complication-free, ensuring a safe surgical margin of healthy tissue. The procedure was completed in 50 minutes. No mucosal perforation or gas escape occurred. Conclusions The combined technique was safe, effective and minimally invasive. No expensive materials were used. Lesion exposure, gastric content leakage, incomplete resection, and excessive normal tissue elimination were avoided. Human trials of this technique may be warranted.
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Referências
- Goto O, 2018, GASTROINTEST ENDOSC, V87, P450, DOI 10.1016/j.gie.2017.08.036
- Goto O, 2016, ENDOSCOPY, V48, P1010, DOI 10.1055/s-0042-111000
- Hiki N, 2008, SURG ENDOSC, V22, P1729, DOI 10.1007/s00464-007-9696-8
- Kikuchi S, 2017, GASTRIC CANCER, V20, P553, DOI 10.1007/s10120-016-0641-1
- Kim Hyung Hun, 2016, Gastrointest Endosc Clin N Am, V26, P335, DOI 10.1016/j.giec.2015.12.011
- Komatsu S, 2016, ANTICANCER RES, V36, P3041
- Maehata T, 2015, WORLD J GASTRO ENDOS, V7, P1208, DOI 10.4253/wjge.v7.i16.1208
- Takeuchi H, 2017, GASTRIC CANCER, V20, pS53, DOI 10.1007/s10120-016-0649-6
- Willingham F F, 2015, GASTROENTEROLOGY RES, V2015, P1