Epizootics due to Yellow Fever Virus in Sao Paulo State, Brazil: viral dissemination to new areas (2016-2017)

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dc.contributor Sistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP
dc.contributor.author CUNHA, Mariana Sequetin
COSTA, Antonio Charlys da FMUSP-HC
FERNANDES, Natalia Coelho Couto de Azevedo
GUERRA, Juliana Mariotti
SANTOS, Fabiana Cristina Pereira dos
NOGUEIRA, Juliana Silva
D'AGOSTINO, Leandro Guariglia
KOMNINAKIS, Shirley Vasconcelos
WITKIN, Steven S. FMUSP-HC
RESSIO, Rodrigo Albergaria
MAEDA, Adriana Yurika
VASAMI, Fernanda Gisele Silva
KAIGAWA, Ursula Mitsue Abreu
AZEVEDO, Lais Sampaio de
FACIOLI, Paloma Alana de Souza
MACEDO, Fernando Luiz Lima
SABINO, Ester Cerdeira FMUSP-HC
LEAL, Elcio
SOUZA, Renato Pereira de
dc.date.issued 2019
dc.identifier.citation SCIENTIFIC REPORTS, v.9, article ID 5474, 13p, 2019
dc.identifier.issn 2045-2322
dc.identifier.uri http://observatorio.fm.usp.br/handle/OPI/31721
dc.description.abstract Beginning in late 2016 Brazil faced the worst outbreak of Yellow Fever in recent decades, mainly located in southeastern rural regions of the country. In the present study we characterize the Yellow Fever Virus (YFV) associated with this outbreak in Sao Paulo State, Brazil. Blood or tissues collected from 430 dead monkeys and 1030 pools containing a total of 5,518 mosquitoes were tested for YFV by quantitative RT-PCR, immunohistochemistry (IHC) and indirect immunofluorescence. A total of 67 monkeys were YFV-positive and 3 pools yielded YFV following culture in a C6/36 cell line. Analysis of five nearly full length genomes of YFV from collected samples was consistent with evidence that the virus associated with the Sao Paulo outbreak originated in Minas Gerais. The phylogenetic analysis also showed that strains involved in the 2016-2017 outbreak in distinct Brazilian states (i.e., Minas Gerais, Rio de Janeiro, Espirito Santo) intermingled in maximum-likelihood and Bayesian trees. Conversely, the strains detected in Sao Paulo formed a monophyletic cluster, suggesting that they were local-adapted. The finding of YFV by RT-PCR in five Callithrix monkeys who were all YFV-negative by histopathology or immunohistochemistry suggests that this YFV lineage circulating in Sao Paulo is associated with different outcomes in Callithrix when compared to other monkeys.
dc.description.sponsorship · FAPESP [2016/01735-2, 2017/00021-9]
· CNPq [400354/2016-0]
dc.language.iso eng
dc.publisher NATURE PUBLISHING GROUP
dc.relation.ispartof Scientific Reports
dc.rights openAccess
dc.subject.other nonhuman-primates; transmission; outbreak
dc.title Epizootics due to Yellow Fever Virus in Sao Paulo State, Brazil: viral dissemination to new areas (2016-2017)
dc.type article
dc.rights.holder Copyright NATURE PUBLISHING GROUP
dc.description.group LIM/58
dc.description.group LIM/46
dc.identifier.doi 10.1038/s41598-019-41950-3
dc.identifier.pmid 30940867
dc.type.category original article
dc.type.version publishedVersion
hcfmusp.author COSTA, Antonio Charlys da:IMT:
hcfmusp.author WITKIN, Steven S.:HC:LIM/58
hcfmusp.author SABINO, Ester Cerdeira:FM:MIP
hcfmusp.author.external · CUNHA, Mariana Sequetin:Adolfo Lutz Inst, Virol Ctr, Vector Borne Dis Grp, Sao Paulo, Brazil
· FERNANDES, Natalia Coelho Couto de Azevedo:Adolfo Lutz Inst, Pathol Ctr, Sao Paulo, Brazil
· GUERRA, Juliana Mariotti:Adolfo Lutz Inst, Pathol Ctr, Sao Paulo, Brazil
· SANTOS, Fabiana Cristina Pereira dos:Adolfo Lutz Inst, Virol Ctr, Vector Borne Dis Grp, Sao Paulo, Brazil
· NOGUEIRA, Juliana Silva:Adolfo Lutz Inst, Virol Ctr, Vector Borne Dis Grp, Sao Paulo, Brazil
· D'AGOSTINO, Leandro Guariglia:Adolfo Lutz Inst, Virol Ctr, Vector Borne Dis Grp, Sao Paulo, Brazil
· KOMNINAKIS, Shirley Vasconcelos:Univ Fed Sao Paulo, Lab Retrovirol, Sao Paulo, Brazil; FMABC, Postgrad Program Hlth Sci, Santo Andre, Brazil
· RESSIO, Rodrigo Albergaria:Adolfo Lutz Inst, Pathol Ctr, Sao Paulo, Brazil
· MAEDA, Adriana Yurika:Adolfo Lutz Inst, Virol Ctr, Vector Borne Dis Grp, Sao Paulo, Brazil
· VASAMI, Fernanda Gisele Silva:Adolfo Lutz Inst, Virol Ctr, Vector Borne Dis Grp, Sao Paulo, Brazil
· KAIGAWA, Ursula Mitsue Abreu:Adolfo Lutz Inst, Virol Ctr, Vector Borne Dis Grp, Sao Paulo, Brazil
· AZEVEDO, Lais Sampaio de:Adolfo Lutz Inst, Virol Ctr, Vector Borne Dis Grp, Sao Paulo, Brazil
· FACIOLI, Paloma Alana de Souza:Adolfo Lutz Inst, Virol Ctr, Vector Borne Dis Grp, Sao Paulo, Brazil
· MACEDO, Fernando Luiz Lima:Adolfo Lutz Inst, Virol Ctr, Vector Borne Dis Grp, Sao Paulo, Brazil
· LEAL, Elcio:Fed Univ Para, Inst Biol Sci, Belem, Para, Brazil
· SOUZA, Renato Pereira de:Adolfo Lutz Inst, Virol Ctr, Vector Borne Dis Grp, Sao Paulo, Brazil
hcfmusp.origem.id WOS:000462990000016
hcfmusp.origem.id 2-s2.0-85063730574
hcfmusp.publisher.city LONDON
hcfmusp.publisher.country ENGLAND
hcfmusp.relation.reference · Amraoui F, 2018, SCI REP-UK, V8, DOI 10.1038/s41598-018-32198-4
· Auguste AJ, 2015, EMERG INFECT DIS, V21, P99, DOI 10.3201/eid2101.140814
· de Almeida MAB, 2012, AM J PRIMATOL, V74, P68, DOI 10.1002/ajp.21010
· Barrett Alan D, 2003, Adv Virus Res, V61, P291, DOI 10.1016/S0065-3527(03)61007-9
· Bielejec F, 2016, MOL BIOL EVOL, V33, P2167, DOI 10.1093/molbev/msw082
· Bonaldo MC, 2017, MEM I OSWALDO CRUZ, V112, P447, DOI 10.1590/0074-02760170134
· Bryant JE, 2003, FEMS IMMUNOL MED MIC, V39, P103, DOI 10.1016/S0928-8244(03)00238-4
· Cardoso JD, 2010, EMERG INFECT DIS, V16, P1918, DOI 10.3201/eid1612.100608
· Fernandes NCCD, 2017, EMERG INFECT DIS, V23, P2038, DOI 10.3201/eid2312.170685
· Couto-Lima D, 2017, SCI REP-UK, V7, DOI 10.1038/s41598-017-05186-3
· Vasconcelos PFD, 2010, REV SAUDE PUBL, V44, P1144, DOI 10.1590/S0034-89102010005000046
· Davis N C, 1930, J Exp Med, V52, P405
· Davis NC, 1929, J EXP MED, V50, P81, DOI 10.1084/jem.50.1.81
· de Rezende IM, 2018, PLOS NEGLECT TROP D, V12, DOI 10.1371/journal.pntd.0006538
· de Souza RP, 2010, J MED VIROL, V82, P175, DOI 10.1002/jmv.21606
· Domingo C, 2012, J CLIN MICROBIOL, V50, P4054, DOI 10.1128/JCM.01799-12
· Emergencia M. S., 2017, B EPIDEMIOLOGICO SVS, V48, P1
· Faria NR, 2018, SCIENCE, V361, P894, DOI 10.1126/science.aat7115
· GUBLER DJ, 1984, AM J TROP MED HYG, V33, P158, DOI 10.4269/ajtmh.1984.33.158
· Larkin MA, 2007, BIOINFORMATICS, V23, P2947, DOI 10.1093/bioinformatics/btm404
· Lemey P, 2009, PLOS COMPUT BIOL, V5, DOI 10.1371/journal.pcbi.1000520
· Ministerio da Saude. Secretaria de Vigilancia em Saude, 2017, 432017 MIN SAUD SECR, P1
· Mir D, 2017, SCI REP-UK, V7, DOI 10.1038/s41598-017-07873-7
· Monath TP, 2015, J CLIN VIROL, V64, P160, DOI 10.1016/j.jcv.2014.08.030
· MONATH TP, 1991, AM J TROP MED HYG, V45, P1
· Moreira-Soto A, 2018, CLIN MICROBIOL INFEC, V24, DOI 10.1016/j.cmi.2018.01.026
· Moreno ES, 2013, REV INST MED TROP SP, V55, P45, DOI 10.1590/S0036-46652013000100008
· Mucci LF, 2016, J AM MOSQUITO CONTR, V32, P329, DOI 10.2987/16-6587.1
· Posada D, 2008, MOL BIOL EVOL, V25, P1253, DOI 10.1093/molbev/msn083
· Price MN, 2010, PLOS ONE, V5, DOI 10.1371/journal.pone.0009490
· Rambaut A, 2018, SYST BIOL, V67, P901, DOI 10.1093/sysbio/syy032
· Souza Renato Pereira de, 2011, Rev. Inst. Med. trop. S. Paulo, V53, P133, DOI 10.1590/S0036-46652011000300004
· Suchard MA, 2018, VIRUS EVOL, V4, DOI 10.1093/ve/vey016
· Tranquilin MV, 2013, REV SOC BRAS MED TRO, V46, P522, DOI 10.1590/0037-8682-0106-2013
· Vasconcelos Pedro Fernando da Costa, 2003, Rev. Soc. Bras. Med. Trop., V36, P275, DOI 10.1590/S0037-86822003000200012
· Vasconcelos PFC, 2004, EMERG INFECT DIS, V10, P1578, DOI 10.3201/eid1009.040197
· Wang E, 1996, VIROLOGY, V225, P274, DOI 10.1006/viro.1996.0601
dc.description.index MEDLINE
hcfmusp.citation.scopus 1
hcfmusp.citation.wos 0
hcfmusp.affiliation.country Brasil


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