Asymptomatic Plasmodium infection in a residual malaria transmission area in the Atlantic Forest region: Implications for elimination

Imagem de Miniatura
Arquivos
art_MIGUEL_Asymptomatic_Plasmodium_infection_in_a_residual_malaria_transmission_2019.PDF (1.65 MB)
Citações na Scopus
8
Tipo de produção
article
Data de publicação
2019
DOI
SciELO
Scopus
Web of Science
PubMed
Título da Revista
ISSN da Revista
Título do Volume
Editora
SOC BRASILEIRA MEDICINA TROPICAL
Autores
MIGUEL, Renata Bortolasse
ALBUQUERQUE, Hermano Gomes
COURA, Jose Rodrigues
SANTOS, Simone da Silva
SILVA, Sidnei da
MOREIRA, Carlos Jose de Carvalho
SUAREZ-MUTIS, Martha Cecilia
Citação
REVISTA DA SOCIEDADE BRASILEIRA DE MEDICINA TROPICAL, v.52, article ID UNSP e20180537, 9p, 2019
Projetos de Pesquisa
Unidades Organizacionais
Fascículo
Resumo
Introduction: Elimination of malaria in areas of interrupted transmission warrants careful case assessment to avoid the reintroduction of this disease. Occasional malaria cases are reported among visitors of the Atlantic Forest area of Brazil, while data on residents of this area are scarce. Methods: A sectional study was carried out to examine 324 individuals living in a municipality where autochthonous cases were detected. Results: Asymptomatic Plasmodium infections were detected in 2.8% of the individuals by polymerase chain reaction (PCR), with one case of P. falciparum (0.3%), two cases of P. vivax (0.6%), and six cases of P. malariae (1.9%). The thick blood smears were negative in all individuals. Serological tests performed in 314 subjects were reactive in 11.1%, with 3.5% for P. falciparum and 7.7% for R. vivax. A subsample of 42 reactive individuals for any Plasmodium species showed R. malariae in 30.9% of specimens. Individuals who entered the Atlantic Forest region were 2.7 times more likely to exhibit reactive serology for P. vivax compared with individuals who did not enter this region (p<0.05). Children <15 years had a higher chance of reactive serology for P. falciparum and P. vivax than individuals >= 15 years of age (p<0.05). Individuals living in the Paraiso district had a higher chance of reactive serology for P. vivax compared to other districts (p<0.05). No associations were found between sex, past exposure to malaria, or serological response to antibodies of any Plasmodium species. Conclusions: The implications of these results for the elimination of malaria were discussed.
Palavras-chave
Malaria, Plasmodium infection, Extra-Amazonian region, Elimination, Rio de Janeiro State
URI
https://observatorio.fm.usp.br/handle/OPI/32034
Referências
  1. Albuquerque HG, 2018, PARASITE VECTOR, V11, DOI 10.1186/s13071-018-2844-2
  2. Marques GRAM, 2008, REV SOC BRAS MED TRO, V41, P386, DOI 10.1590/S0037-86822008000400012
  3. Branquinho M S, 1997, Rev Panam Salud Publica, V2, P189, DOI 10.1590/S1020-49891997000900004
  4. Brasil P, 2017, LANCET GLOB HEALTH, V5, pE1038, DOI 10.1016/S2214-109X(17)30333-9
  5. Carvalho FF, 1950, REV BRAS MALARIOL DO, V3, P473
  6. Cerutti C, 2007, MALARIA J, V6, DOI 10.1186/1475-2875-6-33
  7. Chagas C., 1935, C PROF NUCL COL SAO, P191
  8. Costa AD, 2010, REV SOC BRAS MED TRO, V43, P571, DOI 10.1590/S0037-86822010000500020
  9. Costa DC, 2014, MEM I OSWALDO CRUZ, V109, P641, DOI 10.1590/0074-0276130578
  10. Couto RD, 2010, REV SOC BRAS MED TRO, V43, P52, DOI 10.1590/S0037-86822010000100012
  11. Curado I, 2006, ACTA TROP, V100, P54, DOI 10.1016/j.actatropica.2006.09.010
  12. de Alencar FEC, 2018, MALARIA J, V17, DOI 10.1186/s12936-018-2263-z
  13. de Pina-Costa A, 2014, MEM I OSWALDO CRUZ, V109, P618, DOI 10.1590/0074-0276140228
  14. Deane L. M., 1968, Revista do Instituto de Medicina Tropical de Sao Paulo, V10, P287
  15. DEANE LM, 1992, MEM I OSWALDO CRUZ, V87, P1
  16. Duarte AMRC, 2013, PARASITE VECTOR, V6, DOI 10.1186/1756-3305-6-58
  17. FERREIRA AW, 1988, REV I MED TROP, V30, P137, DOI 10.1590/S0036-46651988000300003
  18. Ferreira MU, 2016, MALARIA J, V15, DOI 10.1186/s12936-016-1335-1
  19. Folegatti PM, 2017, MALARIA J, V16, DOI 10.1186/s12936-017-1762-7
  20. Gadelha P., 1994, Parassitologia (Rome), V36, P175
  21. Greiner M, 2000, PREV VET MED, V45, P23, DOI 10.1016/S0167-5877(00)00115-X
  22. Laporta GZ, 2015, MALARIA J, V14, DOI 10.1186/s12936-015-0680-9
  23. Lupi O, 2014, RESEARCH, V1, DOI [10.13070/rs.pt.DOI:10.13070/rs.pt.1.613, DOI 10.13070/RS.PT.DOI:10.13070/RS.PT.1.613]
  24. de Alvarenga DAM, 2015, MALARIA J, V14, DOI 10.1186/s12936-015-0606-6
  25. Marrelli MT, 2007, MALARIA J, V6, DOI 10.1186/1475-2875-6-127
  26. Maselli LMF, 2014, MALARIA J, V13, DOI 10.1186/1475-2875-13-224
  27. Mattos M. S, 1993, P 4 REUN NAC PESQ MA
  28. Miguel RB, 2014, MEM I OSWALDO CRUZ, V109, P634, DOI 10.1590/0074-0276130558
  29. Ministerio da Saude (MS), 2009, NORMAS MANUAIS TEC A
  30. Moraes HF, 1990, SUCAM SUA ORIGEM SUA
  31. Sallum MAM, 2014, MALARIA J, V13, DOI 10.1186/1475-2875-13-337
  32. Oliveira-Ferreira J, 2010, MALARIA J, V9, DOI 10.1186/1475-2875-9-115
  33. Rezende HR, 2013, J MED ENTOMOL, V50, P598, DOI 10.1603/ME12085
  34. Rezende HR, 2009, NEOTROP ENTOMOL, V38, P272, DOI 10.1590/S1519-566X2009000200017
  35. Duarte AMRD, 2008, ACTA TROP, V107, P179, DOI 10.1016/j.actatropica.2008.05.020
  36. Sanchez Maria Carmen Arroyo, 1993, Revista do Instituto de Medicina Tropical de Sao Paulo, V35, P495, DOI 10.1590/S0036-46651993000600004
  37. SNOUNOU G, 1993, MOL BIOCHEM PARASIT, V58, P283, DOI 10.1016/0166-6851(93)90050-8
  38. Snounou G, 1996, Methods Mol Biol, V50, P263
  39. Suárez-Mutis Martha C., 2007, Rev. Inst. Med. trop. S. Paulo, V49, P159, DOI 10.1590/S0036-46652007000300005
  40. WANDERLEY DMV, 1994, REV SAUDE PUBL, V28, P192, DOI 10.1590/S0034-89101994000300005
  41. WHO, 2016, GLOB TECHN STRAT MAL
  42. World Health Organization (WHO), 2007, GUID PREV REINTR MAL
  43. Yamasaki T, 2011, J MED PRIMATOL, V40, P392, DOI 10.1111/j.1600-0684.2011.00498.x

Coleções
Artigos e Materiais de Revistas Científicas - IMT
Artigos e Materiais de Revistas Científicas - LIM/38
Artigos e Materiais de Revistas Científicas - ODS/03