Fatal evolution of acute Chagas disease in a child from Northern Brazil: factors that determine poor prognosis
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Citações na Scopus
11
Tipo de produção
article
Data de publicação
2019
Editora
INST MEDICINA TROPICAL SAO PAULO
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Autores
ESPER, Helena Rangel
ASSY, Joao Guilherme Pontes Lima
BERRETA, Olivia Campos Pinheiro
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Citação
REVISTA DO INSTITUTO DE MEDICINA TROPICAL DE SAO PAULO, v.61, article ID UNSP e27, 5p, 2019
Resumo
Trypanosoma cruzi is the causative agent of Chagas disease. Nowadays, the transmission in Brazil occurs mainly by oral ingestion of contaminated food that has been associated with more severe clinical manifestations. We report a case of Acute Chagas disease caused by oral transmission in a child from Northern Brazil. In the hospital admission, physical examination showed tachycardia, hepatomegaly. bipalpebral edema and anasarca. Trypanosoma cruzi trypomastigotes were found in microscopy during blood cell count. Twenty-three days before hospitalization, the child had ingested the ""bacaba palm fruit's wine"". Even with the appropriate diagnosis and starting of treatment, she did not survive. Quantitative analysis of Trypanosoma cruzi DNA in a blood sample resulted in 54,053.42 parasite equivalents/mL and the DTU TcIV was identified. The outcome may have been determined by several factors, including the delay to seek a medical service beyond the high parasitemia, detected by qPCR. DTU TcIV could also have influenced the natural history of the disease.
Palavras-chave
Acute Chagas disease, Trypanosoma cruzi, qPCR, Bacaba palm fruit, Children
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