Please use this identifier to cite or link to this item:
https://observatorio.fm.usp.br/handle/OPI/33063
Title: | Associations between children's family environment, spontaneous brain oscillations, and emotional and behavioral problems |
Authors: | SATO, Joao Ricardo; JR, Claudinei Eduardo Biazoli; SALUM, Giovanni Abrahao; GADELHA, Ary; CROSSLEY, Nicolas; VIEIRA, Gilson; ZUGMAN, Andre; PICON, Felipe Almeida; PAN, Pedro Mario; HOEXTER, Marcelo Queiroz; JR, Edson Amaro; ANES, Mauricio; MOURA, Luciana Monteiro; DEL'AQUILLA, Marco Antonio Gomes; MCGUIRE, Philip; ROHDEZ, Luis Augusto; MIGUEL, Euripedes Constantino; BRESSAN, Rodrigo Affonseca; JACKOWSKI, Andrea Parolin |
Citation: | EUROPEAN CHILD & ADOLESCENT PSYCHIATRY, v.28, n.6, p.835-845, 2019 |
Abstract: | The family environment in childhood has a strong effect on mental health outcomes throughout life. This effect is thought to depend at least in part on modifications of neurodevelopment trajectories. In this exploratory study, we sought to investigate whether a feasible resting-state fMRI metric of local spontaneous oscillatory neural activity, the fractional amplitude of low-frequency fluctuations (fALFF), is associated with the levels of children's family coherence and conflict. Moreover, we sought to further explore whether spontaneous activity in the brain areas influenced by family environment would also be associated with a mental health outcome, namely the incidence of behavioral and emotional problems. Resting-state fMRI data from 655 children and adolescents (6-15years old) were examined. The quality of the family environment was found to be positively correlated with fALFF in the left temporal pole and negatively correlated with fALFF in the right orbitofrontal cortex. Remarkably, increased fALFF in the temporal pole was associated with a lower incidence of behavioral and emotional problems, whereas increased fALFF in the orbitofrontal cortex was correlated with a higher incidence. |
Appears in Collections: | Artigos e Materiais de Revistas Científicas - FM/MDR Artigos e Materiais de Revistas Científicas - FM/MPS Artigos e Materiais de Revistas Científicas - LIM/23 Artigos e Materiais de Revistas Científicas - LIM/44 |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
art_SATO_Associations_between_childrens_family_environment_spontaneous_brain_oscillations_2019.PDF Restricted Access | publishedVersion (English) | 832.77 kB | Adobe PDF | View/Open Request a copy |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.