Please use this identifier to cite or link to this item:
https://observatorio.fm.usp.br/handle/OPI/33514
Title: | Spinal Cord Stimulation for Freezing of Gait: From Bench to Bedside |
Authors: | FONOFF, Erich Talamoni; LIMA-PARDINI, Andrea C. De; COELHO, Daniel Boari; MONACO, Bernardo Assumpcao; MACHADO, Birajara; SOUZA, Carolina Pinto de; GHILARDI, Maria Gabriela dos Santos; HAMANI, Clement |
Citation: | FRONTIERS IN NEUROLOGY, v.10, article ID 905, 15p, 2019 |
Abstract: | Spinal cord stimulation (SCS) has been used for the treatment of chronic pain for nearly five decades. With a high degree of efficacy and a low incidence of adverse events, it is now considered to be a suitable therapeutic alternative in most guidelines. Experimental studies suggest that SCS may also be used as a therapy for motor and gait dysfunction in parkinsonian states. The most common and disabling gait dysfunction in patients with Parkinson's disease (PD) is freezing of gait (FoG). We review the evolution of SCS for gait disorders from bench to bedside and discuss potential mechanisms of action, neural substrates, and clinical outcomes. |
Appears in Collections: | Artigos e Materiais de Revistas Científicas - FM/MNE Artigos e Materiais de Revistas Científicas - HC/ICHC Artigos e Materiais de Revistas Científicas - HC/IPq Artigos e Materiais de Revistas Científicas - LIM/45 |
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File | Description | Size | Format | |
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art_FONOFF_Spinal_Cord_Stimulation_for_Freezing_of_Gait_From_2019.PDF | publishedVersion (English) | 2.38 MB | Adobe PDF | View/Open |
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