Early Parental Death and Risk of Psychosis in Offspring: A Six-Country Case-Control Study

Imagem de Miniatura
Arquivos
art_MISRA_Early_Parental_Death_and_Risk_of_Psychosis_in_2019.PDF (909.58 KB)
Citações na Scopus
9
Tipo de produção
article
Data de publicação
2019
DOI
Scopus
Web of Science
PubMed
Título da Revista
ISSN da Revista
Título do Volume
Editora
MDPI
Autores
MISRA, Supriya
GELAYE, Bizu
KOENEN, Karestan C.
WILLIAMS, David R.
BORBA, Christina P. C.
QUATTRONE, Diego
FORTI, Marta Di
CASCIA, Caterina La
BARBERA, Daniele La
TARRICONE, Ilaria
Citação
JOURNAL OF CLINICAL MEDICINE, v.8, n.7, article ID 1081, 13p, 2019
Projetos de Pesquisa
Unidades Organizacionais
Fascículo
Resumo
Evidence for early parental death as a risk factor for psychosis in offspring is inconclusive. We analyzed data from a six-country, case-control study to examine the associations of early parental death, type of death (maternal, paternal, both), and child's age at death with psychosis, both overall and by ethnic group. In fully adjusted multivariable mixed-effects logistic regression models, experiencing early parental death was associated with 1.54-fold greater odds of psychosis (95% confidence interval (CI): 1.23, 1.92). Experiencing maternal death had 2.27-fold greater odds (95% CI: 1.18, 4.37), paternal death had 1.14-fold greater odds (95% CI: 0.79, 1.64), and both deaths had 4.42-fold greater odds (95% CI: 2.57, 7.60) of psychosis compared with no early parental death. Experiencing parental death between 11 and 16 years of age had 2.03-fold greater odds of psychosis than experiencing it before five years of age (95% CI: 1.02, 4.04). In stratified analyses, experiencing the death of both parents had 9.22-fold greater odds of psychosis among minority ethnic groups (95% CI: 2.02-28.02) and no elevated odds among the ethnic majority (odds ratio (OR): 0.96; 95% CI: 0.10-8.97), which could be due in part to the higher prevalence of early parental death among minority ethnic groups but should be interpreted cautiously given the wide confidence intervals.
Palavras-chave
childhood adversities, early parental death, early bereavement, ethnic minorities, psychosis, schizophrenia, population-based, case-control, multi-country
URI
https://observatorio.fm.usp.br/handle/OPI/33548
Referências
  1. Abel KM, 2014, BMJ-BRIT MED J, V348, DOI 10.1136/bmj.f7679
  2. Agid O, 1999, MOL PSYCHIATR, V4, P163, DOI 10.1038/sj.mp.4000473
  3. BIFULCO A, 1994, J CHILD PSYCHOL PSYC, V35, P1419, DOI 10.1111/j.1469-7610.1994.tb01284.x
  4. BIRTCHNELL J, 1974, SOC SCI MED, V8, P335, DOI 10.1016/0037-7856(74)90079-1
  5. BIRTCHNELL J, 1972, PSYCHOL MED, V2, P166, DOI 10.1017/S0033291700040630
  6. BOWLBY J, 1982, AM J ORTHOPSYCHIAT, V52, P664, DOI 10.1111/j.1939-0025.1982.tb01456.x
  7. Cantor-Graae E, 2005, AM J PSYCHIAT, V162, P12, DOI 10.1176/appi.ajp.162.1.12
  8. Clarke MC, 2013, SCHIZOPHR RES, V143, P363, DOI 10.1016/j.schres.2012.11.024
  9. Class QA, 2014, PSYCHOL MED, V44, P71, DOI 10.1017/S0033291713000780
  10. Di Forti M, 2019, LANCET PSYCHIAT, V6, P427, DOI 10.1016/S2215-0366(19)30048-3
  11. Dopp AR, 2012, DEATH STUD, V36, P41, DOI 10.1080/07481187.2011.573175
  12. Dowdney L, 2000, J CHILD PSYCHOL PSYC, V41, P819, DOI 10.1017/S0021963099006216
  13. FINKELSTEIN H, 1988, J CLIN PSYCHOL, V44, P3, DOI 10.1002/1097-4679(198801)44:1<3::AID-JCLP2270440102>3.0.CO;2-1
  14. Furukawa T, 1998, PSYCHIAT RES, V81, P353, DOI 10.1016/S0165-1781(98)00113-9
  15. GRANVILL.KL, 1966, BRIT J PSYCHIAT, V112, P1027, DOI 10.1192/bjp.112.491.1027
  16. Hjorthoj C, 2017, LANCET PSYCHIAT, V4, P295, DOI 10.1016/S2215-0366(17)30078-0
  17. Jacobs JR, 2009, J NERV MENT DIS, V197, P24, DOI 10.1097/NMD.0b013e3181927723
  18. Jongsma HE, 2018, JAMA PSYCHIAT, V75, P36, DOI 10.1001/jamapsychiatry.2017.3554
  19. Laursen TM, 2007, J CLIN PSYCHIAT, V68, P1673, DOI 10.4088/JCP.v68n1106
  20. Laursen TM, 2014, ANNU REV CLIN PSYCHO, V10, P425, DOI 10.1146/annurev-clinpsy-032813-153657
  21. Laursen TM, 2011, PLOS ONE, V6, DOI 10.1371/journal.pone.0024597
  22. Leaune E, 2019, PSYCHOL MED, V49, P545, DOI 10.1017/S0033291718002271
  23. Liang H, 2016, MEDICINE, V95, DOI 10.1097/MD.0000000000002434
  24. Luecken LJ, 2012, SOC PERSONAL PSYCHOL, V6, P243, DOI 10.1111/j.1751-9004.2011.00422.x
  25. McGrath J, 2004, BMC MED, V2, DOI 10.1186/1741-7015-2-13
  26. Morgan C, 2007, PSYCHOL MED, V37, P495, DOI 10.1017/S0033291706009330
  27. Murray RM, 2017, SCHIZOPHRENIA BULL, V43, P1190, DOI 10.1093/schbul/sbx121
  28. Pearlin LI, 2005, J HEALTH SOC BEHAV, V46, P205, DOI 10.1177/002214650504600206
  29. Piotrowski P, 2017, PSYCHIAT DANUB, V29, P108, DOI 10.24869/psyd.2017.108
  30. RAGAN PV, 1986, AM J PSYCHIAT, V143, P153
  31. Rostila M, 2015, SOC SCI MED, V131, P190, DOI 10.1016/j.socscimed.2015.03.012
  32. Schiffman J., 2001, INT J MENTAL HLTH, V30, P3, DOI 10.1080/00207411.2001.11449507
  33. Sorensen HJ, 2014, SCHIZOPHR RES, V153, P214, DOI 10.1016/j.schres.2014.01.008
  34. StataCorp, STAT STAT SOFTW REL
  35. Stilo SA, 2017, PSYCHOL MED, V47, P913, DOI 10.1017/S0033291716002993
  36. Stroebe M, 2007, LANCET, V370, P1960, DOI 10.1016/S0140-6736(07)61816-9
  37. TENNANT C, 1980, PSYCHOL MED, V10, P289, DOI 10.1017/S0033291700044044
  38. Tremblay GC, 1998, CLIN PSYCHOL-SCI PR, V5, P424, DOI 10.1111/j.1468-2850.1998.tb00165.x
  39. Umberson D, 2017, J HEALTH SOC BEHAV, V58, P405, DOI 10.1177/0022146517739317
  40. Umberson D, 2017, P NATL ACAD SCI USA, V114, P915, DOI 10.1073/pnas.1605599114
  41. Varese F, 2012, SCHIZOPHRENIA BULL, V38, P661, DOI 10.1093/schbul/sbs050
  42. WATT NF, 1979, AM J ORTHOPSYCHIAT, V49, P465, DOI 10.1111/j.1939-0025.1979.tb02629.x
  43. Wilcox HC, 2010, J AM ACAD CHILD PSY, V49, P514, DOI 10.1016/j.jaac.2010.01.020
  44. Williams DR, 2019, ANNU REV PUBL HEALTH, V40, P105, DOI 10.1146/annurev-publhealth-040218-043750
  45. Williams DR, 2018, J HEALTH SOC BEHAV, V59, P466, DOI 10.1177/0022146518814251

Coleções
Artigos e Materiais de Revistas Científicas - FM/MPR
Artigos e Materiais de Revistas Científicas - LIM/39
Artigos e Materiais de Revistas Científicas - ODS/03