Hepatitis B: Prevalence and occult infection in HIV-infected patients

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Citações na Scopus
4
Tipo de produção
article
Data de publicação
2020
Título da Revista
ISSN da Revista
Título do Volume
Editora
SOC BRASILEIRA MEDICINA TROPICAL
Autores
CALUX, Samira Julien
SILVA, Vanessa Cristina Martins
COMPRI, Adriana Parise
LEMOS, Marcilio Figueiredo
OBA, Isabel Takano
MOREIRA, Regina Celia
Citação
REVISTA DA SOCIEDADE BRASILEIRA DE MEDICINA TROPICAL, v.53, article ID e20180533, 3p, 2020
Projetos de Pesquisa
Unidades Organizacionais
Fascículo
Resumo
Introduction: HBV and HIV have identical transmission routes. The aim of this study was to determine the prevalence of HBV in HIV patients and to detect the presence of occult HBV infection. Methods: All samples were tested for serology markers and using qPCR. Results: This study included 232 individuals, out of which 36.6% presented with HBV markers and 11.8% presented with HBsAg or HBV-DNA, including 3 patients that showed OBI. Conclusions: We observed a high prevalence of HBV among HIV patients. In addition the results suggest that OBI can occur in patients with serological profiles that are indicative of past infection. Therefore, the application of molecular tests may enable the identification of infections that are not evident solely based on serology.
Palavras-chave
Prevalence, Occult hepatitis B infection, HBV, HIV
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