LIM/08 - Laboratório de Anestesiologia

URI Permanente desta comunidade

https://observatorio.fm.usp.br/handle/OPI/3626
O Laboratório de Anestesiologia é ligado ao Departamento de Cirurgia da Faculdade de Medicina da Universidade de São Paulo (FMUSP).

Linhas de pesquisa: hemodiluição normovolêmica aguda, transporte de oxigênio, hemorragia e sepse; estudo dos métodos dinâmicos na responsividade cardiovascular aos fluidos; ação de substâncias analgésicas em receptores centrais periféricos; métodos aplicativos de imagem e mecânica na modelagem respiratória.

Site oficial: http://limhc.fm.usp.br/portal/lim08-laboratorio-de-anestesiologia/

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Challenges in using the dynamic components of the SOFA score in health care databases
(2024) ROEPKE, R. M. L.; SENDAGIRE, C.; PILCHER, D.
article 0 Citação(ões) na Scopus
VATICAN (Ventilator-Associated Tracheobronchitis Initiative to Conduct Antibiotic Evaluation): protocol for a multicenter randomized open-label trial of watchful waiting versus antimicrobial therapy for ventilator-associated tracheobronchitis
(2024) TOMAZINI, B. M.; BESEN, B. A. M. P.; DIETRICH, C.; GANDARA, A. P. R.; SILVA, D. P.; PINHEIRO, C. C. G.; LUZ, M. N.; MATTOS, R. R. de; REIS, L. F. L.; ROEPKE, R. M. L.; DUARTE, C. S. L. G.; JúNIOR, A. P. N.; VEIGA, V. C.; ARNS, B.; NASCIMENTO, G. M.; PEREIRA, A. J.; CAVALCANTI, A. B.; MACHADO, F. R.; AZEVEDO, L. C. P.
Background: Ventilator-associated tracheobronchitis is a common condition among invasively ventilated patients in intensive care units, for which the best treatment strategy is currently unknown. We designed the VATICAN (Ventilator-Associated Tracheobronchitis Initiative to Conduct Antibiotic Evaluation) trial to assess whether a watchful waiting antibiotic treatment strategy is noninferior to routine antibiotic treatment for ventilator-associated tracheobronchitis regarding days free of mechanical ventilation. Methods: VATICAN is a randomized, controlled, open-label, multicenter noninferiority trial. Patients with suspected ventilator-associated tracheobronchitis without evidence of ventilator-associated pneumonia or hemodynamic instability due to probable infection will be assigned to either a watchful waiting strategy, without antimicrobial administration for ventilator-associated tracheobronchitis and prescription of antimicrobials only in cases of ventilator-associated pneumonia, sepsis or septic shock, or another infectious diagnosis, or to a routine antimicrobial treatment strategy for seven days. The primary outcome will be mechanical ventilation-free days at 28 days, and a key secondary outcome will be ventilator-associated pneumonia-free survival. Through an intention-to-treat framework with a per-protocol sensitivity analysis, the primary outcome analysis will address noninferiority with a 20% margin, which translates to a 1.5 difference in ventilator-free days. Other analyses will follow a superiority analysis framework. Conclusion: The VATICAN trial will follow all national and international ethical standards. We aim to publish the trial in a high-visibility general journal and present it at critical care and infectious disease conferences for dissemination. These results will likely be immediately applicable to the bedside upon trial completion and will provide information with a low risk of bias for guideline development. © 2024, Associacao de Medicina Intensiva Brasileira - AMIB. All rights reserved.
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Evaluation of Nephrotoxicity of Liposomal Amphotericin in Three Administration Regimens for the Treatment of Disseminated Histoplasmosis in AIDS Patients
(2022) GUIMARAES, Marilia Rodovalho; SOARES, Renata B.; SANCHES, Talita R.; GODOY, Cassia S.; FALCI, Diego R.; PASQUALOTTO, Alessandro C.; ANDRADE, Lucia
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Obesity Aggravates Ischemia-Reperfusion Injury (IRI)-Induced AKI in Mice
(2022) SILVA, Igor O. Da; MENEZES, Nicole K. De; JACOBINA, Heloisa D.; PARRA, Antonio C.; SOUZA, Felipe L.; CASTRO, Leticia U. De; ROELOFS, Joris; TAMMARO, Alessandra; SANCHES, Talita R.; ANDRADE, Lucia
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Simulated Impact of Double Antithrombotic Therapy in White and Non-White Patients With Stable Peripheral, Cerebrovascular and/or Coronary Artery Disease
(2024) NEVES, Celso Ricardo Bregalda; REGES, Zally Siqueira; CASELLA, Ivan Benaduce; BERGANTINI NETO, Helio; PINESI, Henrique; FRANCOLIN, Peter Celio; CALDERARO, Daniela; CARDOZO, Francisco Akira Malta; CARAMELLI, Bruno; SERRANO JUNIOR, Carlos Vicente; PRESTI, Calogero; LUCCIA, Nelson De; LEAO, Pedro Puech
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IMMUNE-RELATED TOXOPLASMA GONDII MYOCARDITIS: A CASE REPORT
(2024) MARTINHAGO, Gustavo; SANTOS, Julia; CORSO, Mariana P. Xerfan; FUZISSIMA, Bruno; CARDOZO, Francisco Akira Malta; CALDERARO, Daniela; CARAMELLI, Bruno
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RENAL OUTCOMES OF HEPARIN AND TOCILIZUMAB IN PATIENTS WITH SEVERE COVID-19: A SUBANALYSIS OF THE HEPMAB RANDOMIZED CLINICAL TRIAL (HEPMAB-AKI)
(2024) IKEOKA, Lucas Takeshi; RIBEIRO, Lucas; QUINTAO, Vinicius Caldeira; RIZK, Stephanie Itala; ANDRADE, Fernanda; MELO, Edielle Sant Anna; SANTOS NETO, Nestor; GONZALEZ, Thalita Barbosa; COSTA, Isabela Bispo; ANDRADE, Fernanda Thereza de Almeida; FUKUSHIMA, Julia Tizue; BARROS, Cecilia; KAWAHARA, Lucas; NAKADA, Leticia; KALIL, Roberto; HAJJAR, Ludhmila
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Air Pollution Aggravates Ischemia-Reperfusion-Induced AKI in Mice
(2021) PARRA, Antonio C.; TAMMARO, Alessandra; GRANER, Mariana; ITTO, Lucas Yuji Umesaki; KERS, Jesper; ROELOFS, Joris; VERAS, Mariana; RODRIGUES, Camila E.; FLORQUIN, Sandrine; SANCHES, Talita R.; ANDRADE, Lucia
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Paciente com via aérea difícil
(2024) ALVES, Felipe Guedes Ricarte; QUINTãO, Vinicius Caldeira; RANGEL, Bruno Soares da Silva; RIZK, Stéphanie Itala
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Manejo das arritmias
(2024) SILVEIRA, Saullo Queiroz; TARGUETA, Eduardo Pelegrineti; RIBEIRO, Fernanda Teles; BELLICIERI, Fernando Nardy