LIM/13 - Laboratório de Genética e Cardiologia Molecular

LIM/13 - Laboratório de Genética e Cardiologia Molecular

 

O Laboratório de Genética e Cardiologia Molecular é ligado ao Departamento de Cardiopneumologia da Faculdade de Medicina da Universidade de São Paulo (FMUSP).

Linhas de pesquisa: identificação e caracterização de biomarcadores para utilização em algoritmos de apoio à decisão médica; desenvolvimento de estratégias para reparação de órgãos com baixa capacidade regenerativa; genética das doenças cardiovasculares; evolução das câmaras cardíacas; biologia do desenvolvimento do coração; cardiopatias congênitas; sinalização pelo ácido retinoico; desenvolvimento de vetores virais portadores de genes supressores de tumor e imunoestimuladores para terapia gênica do câncer.

Site oficial: http://www.lims.fm.usp.br/

Coleções nesta comunidade

Submissões recentes

  • SCALCO, Renata C.; GONCALVES, Fernanda T.; SANTOS, Hadassa C.; CARDENA, Mari M. S. G.; TONELLI, Carlos A.; FUNARI, Mariana F. A.; ARACAVA, Rosana M.; PEREIRA, Alexandre C.; FRIDMAN, Cintia; JORGE, Alexander A. L. (SOC BRASIL GENETICA, RIBEIRAO PRET, BRAZIL, 2017)
    Homozygous STAT5B mutations causing growth hormone insensitivity with immune dysfunction were described in 10 patients since 2003, including two Brazilian brothers from the south of Brazil. Our objectives were to evaluate ...
  • CHRISTOPHERSEN, Ingrid E.; RIENSTRA, Michiel; ROSELLI, Carolina; YIN, Xiaoyan; GEELHOED, Bastiaan; BARNARD, John; LIN, Honghuang; ARKING, Dan E.; SMITH, Albert V.; ALBERT, Christine M.; CHAFFIN, Mark; TUCKER, Nathan R.; LI, Molong; KLARIN, Derek; BIHLMEYER, Nathan A.; LOW, Siew-Kee; WEEKE, Peter E.; MUELLER-NURASYID, Martina; SMITH, J. Gustav; BRODY, Jennifer A.; NIEMEIJER, Maartje N.; DOERR, Marcus; TROMPET, Stella; HUFFMAN, Jennifer; GUSTAFSSON, Stefan; SCHURMANN, Claudia; KLEBER, Marcus E.; LYYTIKAINEN, Leo-Pekka; SEPPALA, Ilkka; MALIK, Rainer; HORIMOTO, Andrea R. V. R.; PEREZ, Marco; SINISALO, Juha; AESCHBACHER, Stefanie; THERIAULT, Sebastien; YAO, Jie; RADMANESH, Farid; WEISS, Stefan; TEUMER, Alexander; CHOI, Seung Hoan; WENG, Lu-Chen; CLAUSS, Sebastian; DEO, Rajat; RADER, Daniel J.; SHAH, Svati H.; SUN, Albert; HOPEWELL, Jemma C.; DEBETTE, Stephanie; CHAUHAN, Ganesh; YANG, Qiong; WORRALL, Bradford B.; PARE, Guillaume; KAMATANI, Yoichiro; HAGEMEIJER, Yanick P.; VERWEIJ, Niek; SILAND, Joylene E.; KUBO, Michiaki; SMITH, Jonathan D.; WAGONER, David R. Van; BIS, Joshua C.; PERZ, Siegfried; PSATY, Bruce M.; RIDKER, Paul M.; MAGNANI, Jared W.; HARRIS, Tamara B.; LAUNER, Lenore J.; SHOEMAKER, M. Benjamin; PADMANABHAN, Sandosh; HAESSLER, Jeffrey; BARTZ, Traci M.; WALDENBERGER, Melanie; LICHTNER, Peter; ARENDT, Marina; KRIEGER, Jose E.; KAHONEN, Mika; RISCH, Lorenz; MANSUR, Alfredo J.; PETERS, Annette; SMITH, Blair H.; LIND, Lars; SCOTT, Stuart A.; LU, Yingchang; BOTTINGER, Erwin B.; HERNESNIEMI, Jussi; LINDGREN, Cecilia M.; WONG, Jorge A.; HUANG, Jie; ESKOLA, Markku; MORRIS, Andrew P.; FORD, Ian; REINER, Alex P.; DELGADO, Graciela; CHEN, Lin Y.; CHEN, Yii-Der Ida; SANDHU, Roopinder K.; LI, Man; BOERWINKLE, Eric; EISELE, Lewin; LANNFELT, Lars; ROST, Natalia; ANDERSON, Christopher D.; TAYLOR, Kent D.; CAMPBELL, Archie; MAGNUSSON, Patrik K.; PORTEOUS, David; HOCKING, Lynne J.; VLACHOPOULOU, Efthymia; PEDERSEN, Nancy L.; NIKUS, Kjell; ORHO-MELANDER, Marju; HAMSTEN, Anders; HEERINGA, Jan; DENNY, Joshua C.; KRIEBEL, Jennifer; DARBAR, Dawood; NEWTON-CHEH, Christopher; SHAFFER, Christian; MACFARLANE, Peter W.; HEILMANN-HEIMBACH, Stefanie; ALMGREN, Peter; HUANG, Paul L.; SOTOODEHNIA, Nona; SOLIMAN, Elsayed Z.; UITTERLINDEN, Andre G.; HOFMAN, Albert; FRANCO, Oscar H.; VOELKER, Uwe; JOECKEL, Karl-Heinz; SINNER, Moritz F.; LIN, Henry J.; GUO, Xiuqing; DICHGANS, Martin; INGELSSON, Erik; KOOPERBERG, Charles; MELANDER, Olle; LOOS, Ruth J. F.; LAURIKKA, Jari; CONEN, David; ROSAND, Jonathan; HARST, Pim van der; LOKKI, Marja-Liisa; KATHIRESAN, Sekar; PEREIRA, Alexandre; JUKEMA, J. Wouter; HAYWARD, Caroline; ROTTER, Jerome I.; MAERZ, Winfried; LEHTIMAKI, Terho; STRICKER, Bruno H.; CHUNG, Mina K.; FELIX, Stephan B.; GUDNASON, Vilmundur; ALONSO, Alvaro; RODEN, Dan M.; KAEAEB, Stefan; CHASMAN, Daniel I.; HECKBERT, Susan R.; BENJAMIN, Emelia J.; TANAKA, Toshihiro; LUNETTA, Kathryn L.; LUBITZ, Steven A.; ELLINOR, Patrick T. (NATURE PUBLISHING GROUP, NEW YORK, USA, 2017)
    Atrial fibrillation affects more than 33 million people worldwide and increases the risk of stroke, heart failure, and death(1,2). Fourteen genetic loci have been associated with atrial fibrillation in European and Asian ...
  • DEZAN, Marcia R.; RIBEIRO, Ingrid Helena; OLIVEIRA, Valeria B.; VIEIRA, Juliana B.; GOMES, Francisco C.; FRANCO, Lucas A. M.; VARUZZA, Leonardo; RIBEIRO, Roberto; CHINOCA, Karen Ziza; LEVI, Jose Eduardo; KRIEGER, Jose Eduardo; PEREIRA, Alexandre Costa; GUALANDRO, Sandra F. M.; ROCHA, Vanderson G.; MENDRONE-JUNIOR, Alfredo; SABINO, Ester Cerdeira; DINARDO, Carla Luana (ACADEMIC PRESS INC ELSEVIER SCIENCE, SAN DIEGO, USA, 2017)
    Background: The complexity of Rh genetic variation among sickle cell disease (SCD) patients is high. Conventional molecular assays cannot identify all genetic variants already described for the RH locus as well as foresee ...
  • FRANCO, Andre Silva; FREITAS, Thiago Quadrante; BERNARDO, Wanderley M.; PEREIRA, Rosa Maria R. (LIPPINCOTT WILLIAMS & WILKINS, PHILADELPHIA, USA, 2017)
    Background:Vitamin D serum levels and the presence and activity of rheumatic conditions have been associated. However, many studies are merely observational, and the existent randomized clinical trials were never systematically ...
  • FRANCO, Andre Silva; IUAMOTO, Leandro Ryuchi; PEREIRA, Rosa Maria Rodrigues (HOSPITAL CLINICAS, UNIV SAO PAULO, SAO PAULO, BRAZIL, 2017)
    Rheumatic diseases are very prevalent, affecting about 7 million people in North America; they affect the musculoskeletal system, often with systemic involvement and potential for serious consequences and limitation on ...
  • BALDO, Marcelo P.; CUNHA, Roberto S.; RIBEIRO, Antonio L. P.; LOTUFO, Paulo A.; CHOR, Dora; BARRETO, Sandhi M.; BENSENOR, Isabela M.; PEREIRA, Alexandre C.; MILL, Jose Geraldo (WILEY, HOBOKEN, USA, 2017)
    Background-Black people have a higher risk of developing hypertension and presenting higher vascular stiffening. Our aim was to investigate whether the association between race and aortic stiffness could be explained by ...
  • PEIXOTO-MIRANDA, Erique J.; BITTENCOURT, Marcio S.; STANIAK, Henrique L.; PEREIRA, Alexandre C.; FOPPA, Murilo; SANTOS, Itamar S.; LOTUFO, Paulo A.; BENSENOR, Isabela M. (LIPPINCOTT WILLIAMS & WILKINS, PHILADELPHIA, USA, 2017)
  • MARCHINI, Julio Flavio; ESTEVES, Vinicius; LEMOS, Pedro A. (Atheneu, Rio de Janeiro, BRAZIL, 2016)
  • GOWDAK, Luís Henrique Wolff; KRIEGER, José Eduardo (Atheneu, Rio de Janeiro, BRAZIL, 2016)
  • MARQUES, Cintia Rodrigues; COSTA, Gustavo N. O.; SILVA, Thiago Magalhaes da; OLIVEIRA, Pablo; CRUZ, Alvaro A.; ALCANTARA-NEVES, Neuza Maria; FIACCONE, Rosemeire L.; HORTA, Bernardo L.; HARTWIG, Fernando Pires; BURCHARD, Esteban G.; PINO-YANES, Maria; RODRIGUES, Laura C.; LIMA-COSTA, Maria Fernanda; PEREIRA, Alexandre C.; GOUVEIA, Mateus H.; ANNA, Hanaisa P. Sant; TARAZONA-SANTOS, Eduardo; BARRETO, Mauricio Lima; FIGUEIREDO, Camila Alexandrina (NATURE PUBLISHING GROUP, LONDON, ENGLAND, 2017)
    Several genome-wide association studies have been conducted to investigate the influence of genetic polymorphisms in the development of allergic diseases, but few of them have included the X chromosome. The aim of present ...

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