Artigos e Materiais de Revistas Científicas - LIM/14

Artigos e Materiais de Revistas Científicas - LIM/14

 

A coleção de Artigos e Materiais de Revistas Científicas engloba artigos originais, artigos de revisão, artigos de atualização, artigos técnicos, relatos de experiências, resenhas, ensaios, editoriais, cartas ao editor, debates, notas científicas e técnicas, depoimentos, entrevistas e pontos de vista. Consideram-se como artigos científicos originais os trabalhos redigidos para divulgação de informações e resultados sobre determinada pesquisa científica, publicados em periódico científico após avaliação por outros pesquisadores.

Recent Submissions

  • ALVES, Venancio Avancini Ferreira; RIMOLA, Jordi (THIEME MEDICAL PUBL INC, NEW YORK, USA, 2019)
    Hepatic angiosarcoma and epithelioid hemangioendothelioma (EHE) might be clinically considered a spectrum since, although more frequently presenting indolent behavior, EHE occasionally evolves to high-grade neoplasms. ...
  • POLES, Wagner A.; NISHI, Erika E.; OLIVEIRA, Mariana B. de; EUGENIO, Angela I. P.; ANDRADE, Tathiana A. de; CAMPOS, Antonio Hugo F. M.; CAMPOS JR., Ruy R. de; VASSALLO, Jose; ALVES, Antonio C.; NETO, Cristovam Scapulatempo; PAES, Roberto Antonio Pinto; LANDMAN, Gilles; ZERBINI, Maria Claudia N.; COLLEONI, Gisele W. B. (SPRINGER, NEW YORK, USA, 2019)
    Aging immune deterioration and Epstein-Barr (EBV) intrinsic mechanisms play an essential role in EBV-positive diffuse large B-cell lymphoma (DLBCL) of the elderly (EBV+DLBCLe) pathogenesis, through the expression of viral ...
  • SONG, Alice Tung Wan; ABDALA, Edson; MARTINO, Rodrigo Bronze de; MALBOUISSON, Luis Marcelo Sa; TANIGAWA, Ryan Yukimatsu; ANDRADE, Guilherme Marques; DUCATTI, Liliana; DOI, Andre Mario; PINHO, Joao Renato Rebello; GOMES-GOUVEA, Michele Soares; MALTA, Fernanda de Mello; ARANTES JR., Rubens Macedo; TONACIO, Adriana Coracini; PINTO, Lecio Figueira; HADDAD, Luciana Bertocco Paiva; SANTOS, Vinicius Rocha; PINHEIRO, Rafael Soares Nunes; NACIF, Lucas Souto; GALVAO, Flavio Henrique Ferreira; ALVES, Venancio Avancini Ferreira; ANDRAUS, Wellington; D'ALBUQUERQUE, Luiz Augusto Carneiro (WILEY, HOBOKEN, USA, 2019)
  • RABELO-SANTOS, S. H.; TERMINI, L.; BOCCARDO, E.; DERCHAIN, S.; LONGATTO-FILHO, A.; ANDREOLI, M. A.; COSTA, M. C.; NUNES, R. A. L.; âNGELO-ANDRADE, L. A. L.; VILLA, L. L.; ZEFERINO, L. C. (IMPACT JOURNALS LLC, Brasil, 2018)
    It is well known that persistent infection with high-risk HPV (hr-HPV), mostly HPV-16 and 18, is the main cause of cervical cancer development. Manganese superoxide dismutase (MnSOD or SOD2) are highly expressed in different ...
  • FERNANDES, Locio Flavio Barbour; FREGNANI, Jose Humberto T. G.; STRUNZ, Celia Maria Cassaro; NOGUEIRA, Adriana De Andrade Ramos; LONGATTO-FILHO, Adhemar (SPANDIDOS PUBL LTD, ATHENS, GREECE, 2018)
    The objective of the present study was to evaluate the role of P-selectin in patients with cancer with suspected thromboembolic events (TEEs). Patients with cancer have a four times greater risk of developing TEEs. P-selectin ...
  • PRATI, Bruna; ABJAUDE, Walason da Silva; TERMINI, Lara; MORALE, Mirian; HERBSTER, Suellen; LONGATTO-FILHO, Adhemar; NUNES, Rafaella Almeida Lima; CAMACHO, Lizeth Carolina Cordoba; RABELO-SANTOS, Silvia Helena; ZEFERINO, Luiz Carlos; AGUAYO, Francisco; BOCCARDO, Enrique (NATURE PUBLISHING GROUP, LONDON, ENGLAND, 2019)
    Alterations in specific DNA damage repair mechanisms in the presence of human papillomavirus (HPV) infection have been described in different experimental models. However, the global effect of HPV on the expression of genes ...
  • KORKUT, Anil; ZAIDI, Sobia; KANCHI, Rupa S.; RAO, Shuyun; GOUGH, Nancy R.; SCHULTZ, Andre; LI, Xubin; LORENZI, Philip L.; BERGER, Ashton C.; ROBERTSON, Gordon; KWONG, Lawrence N.; DATTO, Mike; ROSZIK, Jason; LING, Shiyun; RAVIKUMAR, Visweswaran; MANYAM, Ganiraju; RAO, Arvind; SHELLEY, Simon; LIU, Yuexin; JU, Zhenlin; HANSEL, Donna; VELASCO, Guillermo de; PENNATHUR, Arjun; ANDERSEN, Jesper B.; O'ROURKE, Colm J.; OHSHIRO, Kazufumi; JOGUNOORI, Wilma; Bao-Ngoc Nguyen; LI, Shulin; OSMANBEYOGLU, Hatice U.; AJANI, Jaffer A.; MANI, Sendurai A.; HOUSEMAN, Andres; WIZNEROWICZ, Maciej; CHEN, Jian; GU, Shoujun; MA, Wencai; ZHANG, Jiexin; TONG, Pan; CHERNIACK, Andrew D.; DENG, Chuxia; RESAR, Linda; WEINSTEIN, John N.; MISHRA, Lopa; AKBANI, Rehan (CELL PRESS, CAMBRIDGE, USA, 2018)
    We present an integromic analysis of gene alterations that modulate transforming growth factor beta (TGF-beta)Smad-mediated signaling in 9,125 tumor samples across 33 cancer types in The Cancer Genome Atlas (TCGA). Focusing ...
  • MUNARI, Fernanda Franco; CRUVINEL-CARLONI, Adriana; LACERDA, Croider Franco; OLIVEIRA, Antonio Talvane Torres de; SCAPULATEMPO-NETO, Cristovam; SILVA, Sandra Regina Morini da; CREMA, Eduardo; ADAD, Sheila Jorge; RODRIGUES, Maria Aparecida Marchesan; HENRY, Maria Aparecida Coelho Arruda; GUIMARAES, Denise Peixoto; LONGATTO-FILHO, Adhemar; REIS, Rui Manuel (BMC, LONDON, ENGLAND, 2018)
    BackgroundChronic diseases such as chagasic megaesophagus (secondary to Chagas' disease) have been suggested as etiological factors for esophageal squamous cell carcinoma; however, the molecular mechanisms involved are ...
  • FURUYA, Tatiane K.; JACOB, Carlos E.; TOMITAO, Michele T. P.; CAMACHO, Lizeth C. C.; RAMOS, Marcus F. K. P.; ELUF-NETO, Jose; ALVES, Venancio A. F.; ZILBERSTEIN, Bruno; CECCONELLO, Ivan; RIBEIRO JR., Ulysses; CHAMMAS, Roger (MDPI, BASEL, SWITZERLAND, 2018)
    The chronic inflammatory microenvironment and immune cell dysfunction have been described as critical components for gastric tumor initiation and progression. The diffuse subtype is related to poor clinical outcomes, ...
  • MORON, Roberson A.; JACOB, Carlos Eduardo; BRESCIANI, Claudio Jose Caldas; SIMOES, Kleber; ALVES, Venancio Avancini Ferreira; IRYA, Kyoshi; GAMA-RODRIGUES, Joaquim; CECCONELLO, Ivan; LONGATTO-FILHO, Adhemar; ZILBERSTEIN, Bruno (SPANDIDOS PUBL LTD, ATHENS, GREECE, 2018)
    The aim of the present study was to determine the clinical significance of p53 and p21(ras) p21(wafl), p27(kip1) and p16(ink4a) expression in cases of early gastric cancer. A total of 81 patients who had undergone gastrectomy ...
  • SCHAUB, Franz X.; DHANKANI, Varsha; BERGER, Ashton C.; TRIVEDI, Mihir; RICHARDSON, Anne B.; SHAW, Reid; ZHAO, Wei; ZHANG, Xiaoyang; VENTURA, Andrea; LIU, Yuexin; AYER, Donald E.; HURLIN, Peter J.; CHERNIACK, Andrew D.; EISENMAN, Robert N.; BERNARD, Brady; GRANDORI, Carla (CELL PRESS, CAMBRIDGE, USA, 2018)
    Although the MYC oncogene has been implicated in cancer, a systematic assessment of alterations of MYC, related transcription factors, and co-regulatory proteins, forming the proximal MYC network (PMN), across human cancers ...
  • ELLROTT, Kyle; BAILEY, Matthew H.; SAKSENA, Gordon; COVINGTON, Kyle R.; KANDOTH, Cyriac; STEWART, Chip; HESS, Julian; MA, Singer; CHIOTTI, Kami E.; MCLELLAN, Michael; SOFIA, Heidi J.; HUTTER, Carolyn; GETZ, Gad; WHEELER, David; DING, Li (CELL PRESS, CAMBRIDGE, USA, 2018)
    The Cancer Genome Atlas (TCGA) cancer genomics dataset includes over 10,000 tumor-normal exome pairs across 33 different cancer types, in total >400 TB of raw data files requiring analysis. Here we describe the Multi-Center ...
  • RICKETTS, Christopher J.; CUBAS, Aguirre A. de; FAN, Huihui; SMITH, Christof C.; LANG, Martin; REZNIK, Ed; BOWLBY, Reanne; GIBB, Ewan A.; AKBANI, Rehan; BEROUKHIM, Rameen; BOTTARO, Donald P.; CHOUEIRI, Toni K.; GIBBS, Richard A.; GODWIN, Andrew K.; HAAKE, Scott; HAKIMI, A. Ari; HENSKE, Elizabeth P.; HSIEH, James J.; HO, Thai H.; KANCHI, Rupa S.; KRISHNAN, Bhavani; KWAITKOWSKI, David J.; LUI, Wembin; MERINO, Maria J.; MILLS, Gordon B.; MYERS, Jerome; NICKERSON, Michael L.; REUTER, Victor E.; SCHMIDT, Laura S.; SHELLEY, C. Simon; SHEN, Hui; SHUCH, Brian; SIGNORETTI, Sabina; SRINIVASAN, Ramaprasad; TAMBOLI, Pheroze; THOMAS, George; VINCENT, Benjamin G.; VOCKE, Cathy D.; WHEELER, David A.; YANG, Lixing; KIM, William T.; ROBERTSON, A. Gordon; SPELLMAN, Paul T.; RATHMELL, W. Kimryn; LINEHAN, W. Marston (CELL PRESS, CAMBRIDGE, USA, 2018)
    Renal cell carcinoma(RCC) is not a single disease, but several histologically defined cancers with different genetic drivers, clinical courses, and therapeutic responses. The current study evaluated 843 RCC from the three ...
  • CHIU, Hua-Sheng; SOMVANSHI, Sonal; PATEL, Ektaben; CHEN, Ting-Wen; SINGH, Vivek P.; ZORMAN, Barry; PATIL, Sagar L.; PAN, Yinghong; CHATTERJEE, Sujash S.; SOOD, Anil K.; GUNARATNE, Preethi H.; SUMAZIN, Pavel (CELL PRESS, CAMBRIDGE, USA, 2018)
    Long noncoding RNAs (lncRNAs) are commonly dysregulated in tumors, but only a handful are known to play pathophysiological roles in cancer. We inferred lncRNAs that dysregulate cancer pathways, oncogenes, and tumor suppressors ...
  • JAYASINGHE, Reyka G.; CAO, Song; GAO, Qingsong; WENDL, Michael C.; VO, Nam Sy; REYNOLDS, Sheila M.; ZHAO, Yanyan; CLIMENTE-GONZALEZ, Hector; CHAI, Shengjie; WANG, Fang; VARGHESE, Rajees; HUANG, Mo; LIANG, Wen-Wei; WYCZALKOWSKI, Matthew A.; SENGUPTA, Sohini; LI, Zhi; PAYNE, Samuel H.; FENYO, David; MINER, Jeffrey H.; WALTER, Matthew J.; VINCENT, Benjamin; EYRAS, Eduardo; CHEN, Ken; SHMULEVICH, Ilya; CHEN, Feng; DING, Li (CELL PRESS, CAMBRIDGE, USA, 2018)
    For the past decade, cancer genomic studies have focused on mutations leading to splice-site disruption, overlooking those having splice-creating potential. Here, we applied a bioinformatic tool, MiSplice, for the large-scale ...
  • SEILER, Michael; PENG, Shouyong; AGRAWAL, Anant A.; PALACINO, James; TENG, Teng; ZHU, Ping; SMITH, Peter G.; BUONAMICI, Silvia; YU, Lihua (CELL PRESS, CAMBRIDGE, USA, 2018)
    Hotspot mutations in splicing factor genes have been recently reported at high frequency in hematological malignancies, suggesting the importance of RNA splicing in cancer. We analyzed whole-exome sequencing data across ...
  • KNIJNENBURG, Theo A.; WANG, Linghua; ZIMMERMANN, Michael T.; CHAMBWE, Nyasha; GAO, Galen F.; CHERNIACK, Andrew D.; FAN, Huihui; SHEN, Hui; WAY, Gregory P.; GREENE, Casey S.; LIU, Yuexin; AKBANI, Rehan; FENG, Bin; DONEHOWER, Lawrence A.; MILLER, Chase; SHEN, Yang; KARIMI, Mostafa; CHEN, Haoran; KIM, Pora; JIA, Peilin; SHINBROT, Eve; ZHANG, Shaojun; LIU, Jianfang; HU, Hai; BAILEY, Matthew H.; YAU, Christina; WOLF, Denise; ZHAO, Zhongming; WEINSTEIN, John N.; LI, Lei; DING, Li; MILLS, Gordon B.; LAIRD, Peter W.; WHEELER, David A.; SHMULEVICH, Ilya; MONNAT JR., Raymond J.; XIAO, Yonghong; WANG, Chen (CELL PRESS, CAMBRIDGE, USA, 2018)
    DNA damage repair (DDR) pathways modulate cancer risk, progression, and therapeutic response. We systematically analyzed somatic alterations to provide a comprehensive view of DDR deficiency across 33 cancer types. Mutations ...
  • PENG, Xinxin; CHEN, Zhongyuan; FARSHIDFAR, Farshad; XU, Xiaoyan; LORENZI, Philip L.; WANG, Yumeng; CHENG, Feixiong; TAN, Lin; MOJUMDAR, Kamalika; DU, Di; GE, Zhongqi; LI, Jun; THOMAS, George V.; BIRSOY, Kivanc; LIU, Lingxiang; ZHANG, Huiwen; ZHAO, Zhongming; MARCHAND, Calena; WEINSTEIN, John N.; BATHE, Oliver F.; LIANG, Han (CELL PRESS, CAMBRIDGE, USA, 2018)
    Metabolic reprogramming provides critical information for clinical oncology. Using molecular data of 9,125 patient samples from The Cancer Genome Atlas, we identified tumor subtypes in 33 cancer types based on mRNA expression ...
  • GAO, Qingsong; LIANG, Wen-Wei; FOLTZ, Steven M.; MUTHARASU, Gnanavel; JAYASINGHE, Reyka G.; CAO, Song; LIAO, Wen-Wei; REYNOLDS, Sheila M.; WYCZALKOWSKI, Matthew A.; YAO, Lijun; YU, Lihua; SUN, Sam Q.; CHEN, Ken; LAZAR, Alexander J.; FIELDS, Ryan C.; WENDL, Michael C.; TINE, Brian A. Van; VIJ, Ravi; CHEN, Feng; NYKTER, Matti; SHMULEVICH, Ilya; DING, Li (CELL PRESS, CAMBRIDGE, USA, 2018)
    Gene fusions represent an important class of somatic alterations in cancer. We systematically investigated fusions in 9,624 tumors across 33 cancer types using multiple fusion calling tools. We identified a total of 25,664 ...
  • GE, Zhongqi; LEIGHTON, Jake S.; WANG, Yumeng; PENG, Xinxin; CHEN, Zhongyuan; CHEN, Hu; SUN, Yutong; YAO, Fan; LI, Jun; ZHANG, Huiwen; LIU, Jianfang; SHRIVER, Craig D.; HU, Hai; PIWNICA-WORMS, Helen; MA, Li; LIANG, Han (CELL PRESS, CAMBRIDGE, USA, 2018)
    Protein ubiquitination is a dynamic and reversible process of adding single ubiquitin molecules or various ubiquitin chains to target proteins. Here, using multidimensional omic data of 9,125 tumor samples across 33 cancer ...

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