LIM/16 - Laboratório de Fisiopatologia Renal

LIM/16 - Laboratório de Fisiopatologia Renal


O Laboratório de Fisiopatologia Renal é ligado ao Departamento de Clínica Médica da Faculdade de Medicina da Universidade de São Paulo (FMUSP).

Linhas de pesquisa: hipertensão experimental: cloreto de sódio; nefropatias progressivas e doença óssea metabólica (osteodistrofia renal, osteoporose).

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Submissões recentes

  • SANTOS, Francisco V.; CHIAPPA, Gaspar R.; RAMALHO, Sergio Henrique Rodolpho; LIMA, Alexandra Correa Gervazoni Balbuena de; SOUZA, Fausto Stauffer Junqueira de; CAHALIN, Lawrence P.; DURIGAN, Joao Luiz Quagliotti; CASTRO, Isac de; CIPRIANO JR., Gerson (SPRINGER, DORDRECHT, NETHERLANDS, 2018)
    Recent literature suggests that resistance training (RT) improves peak oxygen uptake ( peak), similarly to aerobic exercise (AE) in patients with heart failure (HF), but its effect on cardiac remodeling is controversial. ...
  • CARMO, Wander Barros do; CASTRO, Barbara Bruna Abreu; RODRIGUES, Clovis Antonio; CUSTODIO, Melani Ribeiro; SANDERS-PINHEIRO, Helady (WILEY, HOBOKEN, USA, 2018)
    Phosphate retention and hyperphosphataemia are associated with increased mortality in patients with chronic kidney disease (CKD). We tested the use of cross-linked iron chitosan III (CH-FeCl) as a potential phosphate ...
    As the world's population ages, the incidence of chronic kidney disease (CKD) is growing. There is ongoing debate regarding whether high levels of parathyroid hormone (PTH) would be more common in elderly than young patients, ...
  • SANTOS, Daniela Cristina Dos; CAMARA, Niels Olsen Saraiva; DAVID, Daisa Silva Ribeiro; MALHEIROS, Denise Maria Avancini Costa (WILEY, HOBOKEN, USA, 2017)
    BackgroundThe study investigated whether immunohistochemical features of interstitial and glomerular CD56 and CD16 infiltrates - NK cells markers - could be associated with microcirculation injury scores - peritubular ...
  • RECKZIEGEL, Patricia; FESTUCCIA, William T.; BRITTO, Luiz R. G.; JANG, Karen L. Lopes; ROMAO, Carolina M.; HEIMANN, Joel C.; FOGACA, Manoela V.; RODRIGUES, Naielly S.; SILVA, Nicole R.; GUIMARAES, Francisco S.; EICHLER, Rosangela A. S.; GUPTA, Achla; GOMES, Ivone; DEVI, Lakshmi A.; HEIMANN, Andrea S.; FERRO, Emer S. (NATURE PUBLISHING GROUP, LONDON, ENGLAND, 2017)
    Intracellular peptides generated by limited proteolysis are likely to function inside and outside cells and could represent new possibilities for drug development. Here, we used several conformational-sensitive antibodies ...
  • FANELLI, Camilla; DELLE, Humberto; CAVAGLIERI, Rita Cassia; DOMINGUEZ, Wagner Vasques; NORONHA, Irene L. (HINDAWI LTD, LONDON, ENGLAND, 2017)
    Chronic kidney disease (CKD) is considered a public health problem, assuming epidemic proportions worldwide. In this context, the preponderance of CKD prevalence in male over age-matched female patients is of note. In the ...
  • BARRETO, Fellype Carvalho; OLIVEIRA, Rodrigo Azevedo de; OLIVEIRA, Rodrigo Bueno; JORGETTI, Vanda (INFORMA HEALTHCARE, LONDON, ENGLAND, 2011)
    Introduction: Disturbances of the bone and mineral metabolism are a common complication of chronic kidney disease (CKD); these disturbances are known as CKD-mineral bone disorder (CKD-MBD). A better understanding of the ...
  • LUCATO JR., Rui V.; ABDULKADER, Regina C. R. M.; BARBARO, Katia C.; MENDES, Gloria E.; CASTRO, Isac; BAPTISTA, Maria A. S. F.; CURY, Patricia M.; MALHEIROS, Denise M. C.; SCHOR, Nestor; YU, Luis; BURDMANN, Emmanuel A. (PUBLIC LIBRARY SCIENCE, SAN FRANCISCO, USA, 2011)
    Background: Accidents caused by Loxosceles spider may cause severe systemic reactions, including acute kidney injury (AKI). There are few experimental studies assessing Loxosceles venom effects on kidney function in vivo. ...
  • PEREIRA, Rafael L.; BUSCARIOLLO, Bruna N.; CORREA-COSTA, Matheus; SEMEDO, Patricia; OLIVEIRA, Cassiano D.; REIS, Vanessa O.; MAQUIGUSSA, Edgar; ARAUJO, Ronaldo C.; BRAGA, Tarcio T.; SOARES, Maria F.; MOURA, Ivan C.; MALHEIROS, Denise M. A. C.; PACHECO-SILVA FILHO, Alvaro; KELLER, Alexandre C.; CAMARA, Niels O. S. (NATURE PUBLISHING GROUP, NEW YORK, USA, 2011)
    Focal and segmental glomerulosclerosis (FSGS) is one of the most important causes of end-stage renal failure. The bradykinin B1 receptor has been associated with tissue inflammation and renal fibrosis. To test for a role ...
  • CANCELA, Ana L. E.; OLIVEIRA, Rodrigo B.; GRACIOLLI, Fabiana G.; REIS, Luciene M. dos; BARRETO, Fellype; BARRETO, Daniela V.; CUPPARI, Lilian; JORGETTI, Vanda; CARVALHO, Aluizio B.; CANZIANI, Maria Eugenia; MOYSES, Rosa M. A. (KARGER, BASEL, SWITZERLAND, 2011)
    Background: Fibroblast growth factor 23 (FGF23) concentrations increase early in chronic kidney disease (CKD), and the influence of current CKD-mineral and bone disorder (MBD) therapies on serum FGF23 levels is still under ...

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