LIM/19 - Laboratório de Histocompatibilidade e Imunidade Celular

LIM/19 - Laboratório de Histocompatibilidade e Imunidade Celular

 

O Laboratório de Histocompatibilidade e Imunidade Celular é ligado ao Departamento de Cardiopneumologia da Faculdade de Medicina da Universidade de São Paulo (FMUSP).

Linhas de pesquisa: atuação focada no estudo do reconhecimento imunológico através do complexo trimolecular – molécula apresentadora (MHC), peptídeo e molécula de reconhecimento (LTCR) – e das consequências de tal reconhecimento, através de uma resposta de defesa ou de regulação; estuda como modelo as doenças do coração: febre reumática, Chagas ou aterosclerose e também o transplante de órgãos.

Site oficial: http://www.lims.fm.usp.br/

Coleções nesta comunidade

Submissões recentes

  • TANAKA, Leonardo Y.; LAURINDO, Francisco R. M. (LIPPINCOTT WILLIAMS & WILKINS, PHILADELPHIA, USA, 2018)
  • GIAVINA-BIANCHI, Pedro; AUN, Marcelo V.; KALIL, Jorge (LIPPINCOTT WILLIAMS & WILKINS, PHILADELPHIA, USA, 2018)
    Purpose of reviewThe present review addresses the epidemiology, analyzes the current data and promotes global awareness of drug-induced anaphylaxis.Recent findingsAnaphylaxis is a medical emergency that may cause death! ...
  • LIBERMAN, Marcel; FARIAS-SILVA, Elisângela; LAURINDO, Francisco Rafael Martins (Atheneu, SÃO PAULO, BRAZIL, 2016)
  • AUN, Marcelo Vivolo; KALIL, Jorge; GIAVINA-BIANCHI, Pedro (W B SAUNDERS CO-ELSEVIER INC, PHILADELPHIA, USA, 2017)
    Drugs are among the main triggers of anaphylaxis, but identification of the culprit drug is frequently difficult. To confirm diagnosis of the causative agent, medical records and clinical history are fundamental. There are ...
  • MAGNANI, Diogo M.; SILVEIRA, Cassia G. T.; RICCIARDI, Michael J.; GONZALEZ-NIETO, Lucas; PEDRENO-LOPEZ, Nuria; BAILEY, Varian K.; GUTMAN, Martin J.; MAXWELL, Helen S.; DOMINGUES, Aline; COSTA, Priscilla R.; FERRARI, Lilian; GOULART, Raphaella; MARTINS, Mauricio A.; MARTINEZ-NAVIO, Jose M.; FUCHS, Sebastian P.; KALIL, Jorge; TIMENETSKY, Maria do Carmo; WRAMMERT, Jens; WHITEHEAD, Stephen S.; BURTON, Dennis R.; DESROSIERS, Ronald C.; KALLAS, Esper G.; WATKINS, David I. (AMER SOC MICROBIOLOGY, WASHINGTON, USA, 2017)
    Exposure to dengue virus (DENV) is thought to elicit lifelong immunity, mediated by DENV-neutralizing antibodies (nAbs). However, Abs generated by primary infections confer serotype-specific protection, and immunity against ...
  • GIAVINA-BIANCHI, Pedro; KALIL, Jorge (ELSEVIER SCIENCE BV, AMSTERDAM, NETHERLANDS, 2017)
  • AUN, Marcelo Vivolo; BONAMICHI-SANTOS, Rafael; ARANTES-COSTA, Fernanda Magalhaes; KALIL, Jorge; GIAVINA-BIANCHI, Pedro (DOVE MEDICAL PRESS LTD, ALBANY, NEW ZEALAND, 2017)
    Clinical studies in asthma are not able to clear up all aspects of disease pathophysiology. Animal models have been developed to better understand these mechanisms and to evaluate both safety and efficacy of therapies ...
  • RIBEIRO, Susan Pereira; MILUSH, Jeffrey M.; CUNHA-NETO, Edecio; KAILAS, Esper G.; KALIL, Jorge; PASSERO, Luiz Felipe D.; HUNT, Peter W.; DEEKS, Steven G.; NIXON, Douglas F.; SENGUPTA, Devi (PUBLIC LIBRARY SCIENCE, SAN FRANCISCO, USA, 2017)
  • TERZIAN, Ana Carolina Bernardes; SCHANOSKI, Alessandra Soares; MOTA, Minh' Tasso de Oliveira; SILVA, Rafael Alves da; ESTOFOLETE, Cassia Fernanda; COLOMBO, Tatiana Elias; RAHAL, Paula; HANLEY, Kathryn A.; VASILAKIS, Nikos; KALIL, Jorge; NOGUEIRAL, Mauricio Lacerda (OXFORD UNIV PRESS INC, CARY, USA, 2017)
    Background. The pathogenesis of severe dengue disease involves immune components as biomarkers. The mechanism by which some dengue virus (DENV)-infected individuals progress to severe disease is poorly understood. Most ...
  • CERQUEIRA, Fernanda M.; LAURINDO, Francisco R. M.; KOWALTOWSKI, Alicia J. (PUBLIC LIBRARY SCIENCE, SAN FRANCISCO, USA, 2011)
    Enhanced mitochondrial biogenesis promoted by eNOS activation is believed to play a central role in the beneficial effects of calorie restriction (CR). Since treatment of mice with dinitrophenol (DNP) promotes health and ...

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