LIM/24 - Laboratório de Oncologia Experimental

LIM/24 - Laboratório de Oncologia Experimental

 

O Laboratório de Oncologia Experimental é ligado ao Departamento de Radiologia da Faculdade de Medicina da Universidade de São Paulo (FMUSP).

Linhas de pesquisa: marcadores moleculares em câncer; bases moleculares de tumorigênese, com ênfase em câncer de mama, hepatocarcionoma e melanoma; papel funcional de genes regulados por hormônios esteroides e por vitamina D em câncer de mama; marcadores preditivos à resposta a quimioterapia em câncer de mama, câncer de cabeça e pescoço e melanoma; mecanismos moleculares de quimiossensibilização e quimiorresistência; microRNAs na progressão de câncer de mama; interações celulares no microambiente tumoral como alvo terapêutico; terapias moleculares alvo-dirigidas em oncologia clínica.

Site oficial:http://www.lims.fm.usp.br/

Coleções nesta comunidade

Submissões recentes

  • LYRA, Eduardo Carneiro de; ENCINAS, Giselly; FOLGUEIRA, Maria Aparecida Azevedo Koike (Atheneu, RIO DE JANEIRO, BRAZIL, 2017)
  • MANO, Max; LINCK, Rudinei Diogo Marques (Atheneu, RIO DE JANEIRO, BRAZIL, 2017)
  • EUGENIO, Angela Isabel Pereira; FOOK-ALVES, Veruska Lia; OLIVEIRA, Mariana Bleker de; FERNANDO, Rodrigo Carlini; ZANATTA, Daniela B.; STRAUSS, Bryan Eric; SILVA, Maria Regina Regis; PORCIONATTO, Marimelia Aparecida; COLLEONI, Gisele Wally Braga (IMPACT JOURNALS LLC, ORCHARD PARK, USA, 2017)
    HSP70 connects multiple signaling pathways that work synergistically to protect tumor cells from death by proteotoxic stress and represents a possible target to establish a new approach for multiple myeloma treatment. ...
  • MARTA, Gustavo Nader; POORTMANS, Philip; BARROS, Alfredo C. de; FILASSI, Jose Roberto; FREITAS JUNIOR, Ruffo; AUDISIO, Riccardo A.; MANO, Max Senna; METERISSIAN, Sarkis; DESNYDER, Sarah M.; BUCHHOLZ, Thomas A.; HIJAL, Tarek (ELSEVIER SCI LTD, OXFORD, ENGLAND, 2017)
    Purpose/Objective(s): Skin sparing mastectomy (SSM) and nipple-sparing mastectomy (NSM) have entered routine surgical practice for breast cancer, though their oncologic safety has not been established in randomized controlled ...
  • BONATTO, Naieli; CARLINI, Maria Jose; GARCIA, Simone Aparecida de Bessa; NAGAI, Maria Aparecida (TAYLOR & FRANCIS INC, PHILADELPHIA, USA, 2018)
    PHLDA1 (pleckstrin homology-like domain, family A, member 1) is a multifunctional protein that plays distinct roles in several biological processes including cell death and therefore its altered expression has been identified ...
  • RANJEVA, Sylvia L.; BASKERVILLE, Edward B.; DUKIC, Vanja; VILLA, Luisa L.; LAZCANO-PONCE, Eduardo; GIULIANO, Anna R.; DWYER, Greg; COBEY, Sarah (NATL ACAD SCIENCES, WASHINGTON, USA, 2017)
    The high prevalence of human papillomavirus (HPV), the most common sexually transmitted infection, arises from the coexistence of over 200 genetically distinct types. Accurately predicting the impact of vaccines that target ...
  • COSTA, Allini Mafra da; FREGNANI, Jose Humberto Tavares Guerreiro; PASTREZ, Paula Roberta Aguiar; MARIANO, Vania Sammartino; SCAPULATEMPO NETO, Cristovam; GUIMARAES, Denise Peixoto; OLIVEIRA, Kelly Menezio Giordina de; ZEMI NETO, Said Abdala; NUNES, Emily Montosa; FERREIRA, Silvaneide; SICHERO, Laura; VILLA, Luisa Lina; SYRJANEN, Kari Juhani; LONGATTO-FILHO, Adhemar (F HERNANDEZ, MURCIA, SPAIN, 2018)
    Background. The first publication that associated Human Papillomavirus (HPV) infection and esophageal cancer was published in 1982. However, data are still contradictory and require further investigation. The aim of this ...
  • BARR, Kenneth A.; MARTINEZ, Carlos; MORAN, Jennifer R.; KIM, Ah-Ram; RAMOS, Alexandre F.; REINITZ, John (BIOMED CENTRAL LTD, LONDON, ENGLAND, 2017)
    Background: Models that incorporate specific chemical mechanisms have been successful in describing the activity of Drosophila developmental enhancers as a function of underlying transcription factor binding motifs. Despite ...
  • NOGUEIRA, Pericles Alves; ABRAHAO, Regina Maura Cabral de Melo; GALESI, Vera Maria Neder; LOPEZ, Rossana Veronica Mendoza (REVISTA DE SAUDE PUBLICA, SAO PAULO, BRAZIL, 2018)
    OBJECTIVE: Estimate the prevalence of active tuberculosis and latent tuberculosis infection among the staff that is in contact and the staff that is not in contact with prisoners, and investigate factors associated with ...
  • AMORIM, Aline Teixeira; MARQUES, Lucas Miranda; CAMPOS, Guilherme Barreto; LOBAO, Tassia Neves; LINO, Vanesca de Souza; CINTRA, Ricardo Cesar; ANDREOLI, Maria Antonieta; VILLA, Luisa Lina; BOCCARDO, Enrique; BRAGA JUNIOR, Antonio Carlos Ricardo; LOPEZ, Rossana Veronica Mendoza; SANTOS, Djanilson Barbosa dos; SOUZA, Gerson Maciel de; ROMANO, Carla Cristina; TIMENETSKY, Jorge (BIOMED CENTRAL LTD, LONDON, ENGLAND, 2017)
    Background: Some sexually transmitted infectious agents, such as Chlamydia trachomatis and Herpes simplex, cause local inflammation, and could contribute to Human Papillomavirus (HPV) and cervical lesion progression. Thus, ...

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