LIM/27 - Laboratório de Neurociências

LIM/27 - Laboratório de Neurociências

 

O Laboratório de Neurociências é ligado ao Departamento de Neurologia da Faculdade de Medicina da Universidade de São Paulo (FMUSP).

Linhas de pesquisa: expressão gênica em amostras cerebrais e outros tecidos derivados de pacientes com doenças neuropsiquiátricas; farmacogenética; biologia celular e culturas primárias de neurônios; ressonância magnética e espectroscopia; metabolismo de fosfolípedes na membrana neuronal; estudos clínico-epidemiológicos e ensaios farmacêuticos; biomarcadores moleculares em doenças neuropsiquiátricas; lítio e neuroproteção na doença de Alzheimer, modelos animais em doenças neuropsiquiátricas.

Site oficial: http://www.lims.fm.usp.br/

Coleções nesta comunidade

Submissões recentes

  • HENGARTNER, Michael P.; PASSALACQUA, Silvia; ANDREAE, Andreas; ROSSLER, Wulf; WYL, Agnes von (SAGE PUBLICATIONS LTD, LONDON, ENGLAND, 2017)
    Background: The association between social support, readmissions and psychopathology following discharge from psychiatric hospitals is not clear. Aims: To examine the prospective effects of perceived social support on ...
  • FALKAI, Peter; MALCHOW, Berend; SCHMITT, Andrea (LIPPINCOTT WILLIAMS & WILKINS, PHILADELPHIA, USA, 2017)
    Purpose of review Schizophrenia is a severe neuropsychiatric disorder with incomplete remission because of negative and cognitive symptoms in a large proportion of patients. Antipsychotic medication is successful in ...
  • CAFE-MENDES, C. C.; FERRO, E. S.; TORRAO, A. S.; CRUNFLI, F.; RIOLI, V.; SCHMITT, A.; FALKAI, P.; BRITTO, L. R.; TURCK, C. W.; MARTINS-DE-SOUZA, D. (ELSEVIER SCIENCE BV, AMSTERDAM, NETHERLANDS, 2017)
    Schizophrenia is a complex disorder hypothesized to develop from a combination of genetic, neurodevelopmental, and environmental factors. Molecules that are directly involved in the pathogenesis of schizophrenia and may ...
  • FALKAI, Peter; MALCHOW, Berend; WETZESTEIN, Katharina; NOWASTOWSKI, Verena; BERNSTEIN, Hans-Gert; STEINER, Johann; SCHNEIDER-AXMANN, Thomas; KRAUS, Theo; HASAN, Alkomiet; BOGERTS, Bernhard; SCHMITZ, Christoph; SCHMITT, Andrea (OXFORD UNIV PRESS, OXFORD, ENGLAND, 2016)
    The hippocampus is involved in cognition as well as emotion, with deficits in both domains consistently described in schizophrenia. Moreover, the whole volumes of both the anterior and posterior region have been reported ...
  • BAHARI-JAVAN, Sanaz; VARBANOV, Hristo; HALDER, Rashi; BENITO, Eva; KAURANI, Lalit; BURKHARDT, Susanne; ANDERSON-SCHMIDT, Heike; ANGHELESCU, Ion; BUDDE, Monika; STILLING, Roman M.; COSTA, Joan; MEDINA, Juan; DIETRICH, Detlef E.; FIGGE, Christian; FOLKERTS, Here; GADE, Katrin; HEILBRONNER, Urs; KOLLER, Manfred; KONRAD, Carsten; NUSSBECK, Sara Y.; SCHERK, Harald; SPITZER, Carsten; STIERL, Sebastian; STOECKEL, Judith; THIEL, Andreas; HAGEN, Martin von; ZIMMERMANN, Joerg; ZITZELSBERGER, Antje; SCHULZ, Sybille; SCHMITT, Andrea; DELALLE, Ivana; FALKAI, Peter; SCHULZE, Thomas G.; DITYATEV, Alexander; SANANBENESI, Farahnaz; FISCHER, Andre (NATL ACAD SCIENCES, WASHINGTON, USA, 2017)
    Schizophrenia is a devastating disease that arises on the background of genetic predisposition and environmental risk factors, such as early life stress (ELS). In this study, we show that ELS-induced schizophrenia-like ...
  • PAPIOL, S.; POPOVIC, D.; KEESER, D.; HASAN, A.; SCHNEIDER-AXMANN, T.; DEGENHARDT, F.; ROSSNER, M. J.; BICKEBOELLER, H.; SCHMITT, A.; FALKAI, P.; MALCHOW, B. (NATURE PUBLISHING GROUP, NEW YORK, USA, 2017)
    Preliminary studies suggest that, besides improving cognition, aerobic exercise might increase hippocampal volume in schizophrenia patients; however, results are not consistent. Individual mechanisms of volume changes are ...
  • DONDE, Clement; AMAD, Ali; NIETO, Isabel; BRUNONI, Andre Russowsky; NEUFELD, Nicholas H.; BELLIVIER, Frank; POULET, Emmanuel; GEOFFROY, Pierre-Alexis (PERGAMON-ELSEVIER SCIENCE LTD, OXFORD, ENGLAND, 2017)
    Objective: Bipolar disorder (BD) is a severe and recurrent brain disorder that can manifest in manic or depressive episodes. Transcranial Direct Current Stimulation (tDCS) has been proposed as a novel therapeutic modality ...
  • BRUNONI, A. R.; MOFFA, A. H.; SAMPAIO-JUNIOR, B.; BORRIONE, L.; MORENO, M. L.; FERNANDES, R. A.; VERONEZI, B. P.; NOGUEIRA, B. S.; APARICIO, L. V. M.; RAZZA, L. B.; CHAMORRO, R.; TORT, L. C.; FRAGUAS, R.; LOTUFO, P. A.; GATTAZ, W. F.; FREGNI, F.; BENSENOR, I. M. (MASSACHUSETTS MEDICAL SOC, WALTHAM, USA, 2017)
    BACKGROUND We compared transcranial direct-current stimulation (tDCS) with a selective serotonin-reuptake inhibitor for the treatment of depression. METHODS In a single-center, double-blind, noninferiority trial involving ...
  • MIRANDEZ, Roberta M.; APRAHAMIAN, Ivan; TALIB, Leda L.; FORLENZA, Orestes V.; RADANOVIC, Marcia (CAMBRIDGE UNIV PRESS, NEW YORK, USA, 2017)
    Background: Verbal fluency (VF) tasks are widely used in neuropsychological evaluations, as a measure of executive/semantic dysfunction. The revised criteria for Alzheimer's disease (AD) diagnosis (National Institute on ...
  • LOCH, Alexandre Andrade; CHIANCA, Camille; ALVES, Tania Maria; FREITAS, Elder Lanzani; HORTENCIO, Lucas; ANDRADE, Julio Cesar; BILT, Martinus Theodorus Van de; FONTONI, Marcos Roberto; SERPA, Mauricio H.; GATTAZ, Wagner Farid; ROESSLER, Wulf (ELSEVIER IRELAND LTD, CLARE, IRELAND, 2017)
    The aim of our study was to assess psychotic-like experiences in the general population aged 18-30 years old of the city of Sao Paulo, Brazil. A household survey was conducted with 1950 young-adults randomly drawn from the ...

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