LIM/29 - Laboratório de Nefrologia Celular, Genética e Molecular

LIM/29 - Laboratório de Nefrologia Celular, Genética e Molecular

 

O Laboratório de Nefrologia Celular, Genética e Molecular é ligado ao Departamento de Clínica Médica da Faculdade de Medicina da Universidade de São Paulo (FMUSP).

Linhas de pesquisa: patogênese molecular e celular da doença renal policística autossômica recessiva; células-tronco e doenças renais; mecanismos inflamatórios envolvidos na fibrogênese das doenças renais e análise de estratégias antifibróticas; e mecanismos envolvidos na rejeição e tolerância ao enxerto em transplante de órgãos: rim, pâncreas e transplante experimental de rim e ilhotas pancreáticas.

Site oficial: http://www.lims.fm.usp.br/

Coleções nesta comunidade

Submissões recentes

  • FANELLI, Camilla; DELLE, Humberto; CAVAGLIERI, Rita Cassia; DOMINGUEZ, Wagner Vasques; NORONHA, Irene L. (HINDAWI LTD, LONDON, ENGLAND, 2017)
    Chronic kidney disease (CKD) is considered a public health problem, assuming epidemic proportions worldwide. In this context, the preponderance of CKD prevalence in male over age-matched female patients is of note. In the ...
  • CASTRO-SILVA, A. N.; FREIRE, A. O.; GRINBAUM, R. S.; ARAUJO, M. R. Elmor de; ABENSUR, H.; ARAUJO, M. R. T.; ROMAO JR., J. E.; SAMPAIO, J. L. M.; NORONHA, I. L. (WILEY-BLACKWELL PUBLISHING, INC, MALDEN, USA, 2011)
    P>Mycobacterium haemophilum is a slow-growing nontuberculous mycobacterium that can cause disease in both immunocompetent and immunocompromised patients. The most common clinical presentations of infection are the appearance ...
  • BECKER, Luis E.; KOLEGANOVA, Nadezda; PIECHA, Grzegorz; NORONHA, Irene L.; ZEIER, Martin; GELDYYEV, Aman; KOEKENY, Gabor; RITZ, Eberhard; GROSS, Marie-Luise (AMER PHYSIOLOGICAL SOC, BETHESDA, USA, 2011)
    Becker LE, Koleganova N, Piecha G, Noronha IL, Zeier M, Geldyyev A, Kokeny G, Ritz E, Gross ML. Effect of paricalcitol and calcitriol on aortic wall remodeling in uninephrectomized ApoE knockout mice. Am J Physiol Renal ...
  • FERREIRA, Frederico M.; OLIVEIRA, Leandro C.; GERMINO, Gregory G.; ONUCHIC, Jose N.; ONUCHIC, Luiz F. (NATL ACAD SCIENCES, WASHINGTON, USA, 2011)
    Mutations in PKD2 are responsible for approximately 15% of the autosomal dominant polycystic kidney disease cases. This gene encodes polycystin-2, a calcium-permeable cation channel whose C-terminal intracytosolic tail ...
  • BASTOS, A. P.; ONUCHIC, L. F. (ASSOC BRAS DIVULG CIENTIFICA, SAO PAULO, BRAZIL, 2011)
    Autosomal dominant polycystic kidney disease (ADPKD) is one of the most common human life-threatening monogenic disorders. The disease is characterized by bilateral, progressive renal cystogenesis and cyst and kidney ...
  • BALBO, Bruno Eduardo Pedroso; VICENTINI, Fabio Carvalho; MAZZUCCHI, Eduardo; ONUCHIC, Luiz Fernando (NATURE PUBLISHING GROUP, NEW YORK, USA, 2011)
  • NORONHA, Irene L.; CAVAGLIERI, Rita C.; JANZ, Felipe L.; DUARTE, Sergio A.; LOPES, Marco A. B.; ZUGAIB, Marcelo; BYDLOWSKI, Sergio P. (NATURE PUBLISHING GROUP, NEW YORK, USA, 2011)
    Amniotic fluid (AF) contains a variety of cell types derived from fetal tissues that can easily grow in culture. These cells can be obtained during amniocentesis for prenatal screening of fetal genetic diseases, usually ...
  • MORENO, Carina Nilsen; SIQUEIRA, Raquel Cruzeiro de; NORONHA, Irene L. (ASSOC MEDICA BRASILEIRA, SAO PAULO, BRAZIL, 2011)
    Kidney transplantation in HIV infected patients This review presents current considerations for renal transplantation in HIV patients. In the last decade, with the advent of highly active antiretroviral therapy (HAART), ...
  • KAIMORI, Jun-ya; LIN, Cheng-Chao; OUTEDA, Patricia; GARCIA-GONZALEZ, Miguel A.; MENEZES, Luis F.; HARTUNG, Erum A.; LI, Ao; WU, Guanqing; FUJITA, Hideaki; SATO, Yasunori; NAKANUMA, Yasuni; YAMAMOTO, Satoko; ICHIMARU, Naotsugu; TAKAHARA, Shiro; ISAKA, Yoshitaka; WATNICK, Terry; ONUCHIC, Luiz F.; GUAY-WOODFORD, Lisa M.; GERMINO, Gregory G. (NATURE PUBLISHING GROUP, LONDON, ENGLAND, 2017)
    Autosomal recessive polycystic kidney disease (ARPKD) is an important childhood nephropathy, occurring 1 in 20,000 live births. The major clinical phenotypes are expressed in the kidney with dilatation of the collecting ...
  • COSTALONGA, Elerson C.; FREITAS, Luiza J. de; ARAGONE, Deise da S. P.; SILVA, Filipe M. O.; NORONHA, Irene L. (PUBLIC LIBRARY SCIENCE, SAN FRANCISCO, USA, 2017)
    Background Progressive fibrous thickening of the peritoneal membrane is a complication of long-term peritoneal dialysis (PD). TGF-beta/Smad pathway activation, inflammation, and neoangiogenesis play important roles in ...

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