LIM/33 - Laboratório de Oftalmologia

O Laboratório de Oftalmologia é ligado ao Departamento de oftalmologia e otorrinolaringologia da Faculdade de Medicina da Universidade de São Paulo (FMUSP).

Linhas de pesquisa: fatores biopsicossociais na prevenção da cegueira; modelos de avaliação dos distúrbios da fisiologia do humor aquoso; investigação e tratamento das afecções da retina; protocolos de investigação e tratamento cirúrgico da disfunções dos anexos oculares e imunopatologia da superfície ocular.

Site oficial: http://limhc.fm.usp.br/portal/lim33-laboratorio-de-oftalmologia/

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Recent Submissions

  1. Retinal arterial macroaneurysms in patients recovered from COVID-19

    REVISTA BRASILEIRA DE OFTALMOLOGIA, v.82, p.e0034, 2023

    ABSTRACT This is a case series about retinal arterial macroaneurysms in three patients recovered from COVID-19. None of them had previous past ocular and systemic history. The first patient was a 47-year-old man, with best-corrected visual acuity of 20/20 in both eyes. He presented a cotton wool ...

  2. Situation of ophthalmology education in Brazil: versus demand

    ARQUIVOS BRASILEIROS DE OFTALMOLOGIA, v.87, n.6, article ID e20210482, 5p, 2024

    Purpose: The number of medical schools in Brazil has increased in recentyears; however, vacancies for specialization in ophthalmology probably have not kept up with the growing demand. This study wants to estimate the increase in medical schools, the demand for ophthalmology specialization, and e...

  3. OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY BIOMARKERS AND MICROPERIMETRY FEATURES IN BEHÇET'S UVEITIS

    RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES, v.43, n.10, p.1680-1690, 2023

    Purpose: To evaluate the parafoveal macular microvasculature and the macular function in patients with retinal vasculitis associated with Beh & ccedil;et's uveitis.Methods: In 14 patients with inactive Beh & ccedil;et's uveitis and 26 control individuals (13 with nonocul...

  4. Transforming growth factor beta-3 localization in the corneal response to epithelial-stromal injury and effects on corneal fibroblast transition to myofibroblasts

    EXPERIMENTAL EYE RESEARCH, v.235, article ID 109631, 16p, 2023

    The purpose of this study was to evaluate the localization of TGF beta-3 in situ in unwounded rabbit corneas and corneas that had epithelial-stromal injuries produced by photorefractive keratectomy (PRK) in rabbits and to evaluate the in vitro effects of TGF beta-3 compared to TGF beta-1 on alpha...

  5. Topical Losartan Decreases Myofibroblast Generation But Not Corneal Opacity After Surface Blast-Simulating Irregular PTK in Rabbits

    TRANSLATIONAL VISION SCIENCE & TECHNOLOGY, v.12, n.9, article ID 20, 10p, 2023

    Purpose: To evaluate the efficacy of topical losartan after blast injury-simulating irregular phototherapeutic keratectomy (PTK) in rabbits.Methods: Twelve NZW rabbits underwent 100 pulse 6.5 mm diameter PTK over a metal screen to generate severe surface irregularity and inhibit epithelial baseme...

  6. The influence of topical anesthetic and fluorescein on non-contact tonometry measurements using ultra-high-speed dynamic Scheimpflug

    SCIENTIFIC REPORTS, v.13, n.1, article ID 17864, 7p, 2023

    This study aimed to investigate the effects of topical anesthetic and fluorescein drops on intraocular pressure (IOP), central corneal thickness (CCT) and biomechanical properties as measured by Corvis ST (CST-Oculus; Wezlar, Germany) in healthy eyes. A cross-sectional observational study was con...

  7. Profile of patients with essential blepharospasm and hemifacial spasm in the two largest ophthalmology reference centers in Brazil

    ARQUIVOS BRASILEIROS DE OFTALMOLOGIA, v.87, n.6, article ID e20220160, 6p, 2024

    Purpose: Information is scarce regarding the comprehensive profile of patients with essential blepharospasm and hemifacial spasm in Brazil. The present study aimed to assess the clinical features of patients with these conditions, followed up in two reference centers in Brazil. Methods: The study...

  8. Immunoglobulin A Antibodies Against Myelin Oligodendrocyte Glycoprotein in a Subgroup of Patients With Central Nervous System Demyelination

    JAMA NEUROLOGY, v.80, n.9, p.989-995, 2023

    IMPORTANCE Differential diagnosis of patients with seronegative demyelinating central nervous system (CNS) disease is challenging. In this regard, evidence suggests that immunoglobulin (Ig) A plays a role in the pathogenesis of different autoimmune diseases. Yet little is known about the presence...

  9. Assessing Keratoconus Progression

    Tzelikis, P. F.; Silva, L. N. P.; Rocha, G.. Assessing Keratoconus Progression. In: . Keratoconus: A Comprehensive Guide to Diagnosis and Treatment: SPRINGER INTERNATIONAL PUBLISHING, 2022. p.185-198.

    A variety of methods have been described to both evaluate and document keratoconus progression. In a clinical practice, the ophthalmologist usually evaluates two scans of a patient performed a few months apart to estimate if there is a progression of the disease. Today, besides corneal keratometr...

  10. Clinical Presentation and Evolution of Keratoconus

    Cresta, F. B.; Orlandin, L. F.; Lucas, M. B.. Clinical Presentation and Evolution of Keratoconus. In: . Keratoconus: A Comprehensive Guide to Diagnosis and Treatment: SPRINGER INTERNATIONAL PUBLISHING, 2022. p.3-12.

    Corneal ectasia is a group of disorders affecting the shape of the cornea. Keratoconus is the most common primary ectasia. It usually appears in the second decade of the life and affects both genders and all ethnicities. It is bilateral, usually asymmetric, and characterized by central or paracen...