Biological therapies in breast cancer: Common toxicities and management strategies
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Citações na Scopus
21
Tipo de produção
article
Data de publicação
2013
Editora
CHURCHILL LIVINGSTONE
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Citação
BREAST, v.22, n.6, p.1009-1018, 2013
Resumo
In recent years, a number of new molecules e commonly known as biological therapies e have been approved or are in late stages of regulatory evaluation for the treatment of advanced breast cancer. These innovative compounds have improved treatment efficacy and have probably contributed to the increase in survival length observed in some breast cancer subtypes. However, these agents are not deprived of toxicity, which can impair quality of life and may occasionally be life-threatening. In this article, we reviewed the most common toxicities associated with these drugs and provided a number of practical recommendations on their optimal clinical management.
Palavras-chave
Breast cancer, Trastuzumab, Pertuzumab, Lapatinib, Bevacizumab, Trastuzumab-emtansine, Everolimus
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