Cardiovascular risk factors in outpatients with bipolar disorder: a report from the Brazilian Research Network in Bipolar Disorder

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dc.contributor Sistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP
dc.contributor.author GOMES, Fabiano A.
ALMEIDA, Karla M. FMUSP-HC
MAGALHAES, Pedro V.
CAETANO, Sheila C. FMUSP-HC
KAUER-SANT'ANNA, Marcia
LAFER, Beny FMUSP-HC
KAPCZINSKI, Flavio
dc.date.issued 2013
dc.identifier.citation REVISTA BRASILEIRA DE PSIQUIATRIA, v.35, n.2, p.126-130, 2013
dc.identifier.issn 1516-4446
dc.identifier.uri http://observatorio.fm.usp.br/handle/OPI/4224
dc.description.abstract Objective: Bipolar disorder (BD) is associated with significant morbidity and mortality due to comorbid general medical conditions, particularly cardiovascular disease. This study is the first report of the Brazilian Research Network in Bipolar Disorder (BRN-BD) that aims to evaluate the prevalence and clinical correlates of cardiovascular risk factors among Brazilian patients with BD. Methods: A cross-sectional study of 159 patients with DSM-IV BD, 18 years or older, consecutively recruited from the Bipolar Research Program (PROMAN) in Sao Paulo and the Bipolar Disorder Program (PROTAHBI) in Porto Alegre. Clinical, demographic, anthropometric, and metabolic variables were systematically assessed. Results: High rates of smoking (27%), physical inactivity (64.9%), alcohol use disorders (20.8%), elevated fasting glucose (26.4%), diabetes (13.2%), hypertension (38.4%), hypertriglyceridemia (25.8%), low HDL-cholesterol (27.7%), general (38.4%) and abdominal obesity (59.1%) were found in the sample. Male patients were more likely to have alcohol use disorders, diabetes, and hypertriglyceridemia, whereas female patients showed higher prevalence of abdominal obesity. Variables such as medication use pattern, alcohol use disorder, and physical activity were associated with selected cardiovascular risk factors in the multivariable analysis. Conclusion: This report of the BRN-BD provides new data regarding prevalence rates and associated cardiovascular risk factors in Brazilian outpatients with BD. There is a need for increasing both awareness and recognition about metabolic and cardiovascular diseases in this patient population.
dc.description.sponsorship · Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPq)
· Fundo de Incentivo a Pesquisa - Hospital de Clinicas de Porto Alegre (FIPE-HCPA), Brazil
dc.language.iso eng
dc.publisher ASSOC BRASILEIRA PSIQUIATRIA
dc.relation.ispartof Revista Brasileira de Psiquiatria
dc.rights openAccess
dc.subject Bipolar disorder; cardiovascular risk factors; comorbidity
dc.subject.other metabolic syndrome; i-disorder; medical comorbidities; mood disorders; united-states; obesity; prevalence; burden; schizophrenia; psychiatrists
dc.title Cardiovascular risk factors in outpatients with bipolar disorder: a report from the Brazilian Research Network in Bipolar Disorder
dc.type article
dc.rights.holder Copyright ASSOC BRASILEIRA PSIQUIATRIA
dc.description.group LIM/21
dc.identifier.doi 10.1590/1516-4446-2011-0768
dc.identifier.pmid 23904016
dc.type.category original article
dc.type.version publishedVersion
hcfmusp.author ALMEIDA, Karla M.:HC:IPQ
hcfmusp.author CAETANO, Sheila C.:HC:IPQ
hcfmusp.author LAFER, Beny:FM:MPS
hcfmusp.author.external · GOMES, Fabiano A.:Univ Fed Rio Grande do Sul, HCPA, Bipolar Disorder Program PROTAHBI, Porto Alegre, RS, Brazil; Univ Fed Rio Grande do Sul, HCPA, Natl Sci & Technol Inst Translat Med INCT TM, Porto Alegre, RS, Brazil
· MAGALHAES, Pedro V.:Univ Fed Rio Grande do Sul, HCPA, Bipolar Disorder Program PROTAHBI, Porto Alegre, RS, Brazil; Univ Fed Rio Grande do Sul, HCPA, Natl Sci & Technol Inst Translat Med INCT TM, Porto Alegre, RS, Brazil
· KAUER-SANT'ANNA, Marcia:Univ Fed Rio Grande do Sul, HCPA, Bipolar Disorder Program PROTAHBI, Porto Alegre, RS, Brazil; Univ Fed Rio Grande do Sul, HCPA, Natl Sci & Technol Inst Translat Med INCT TM, Porto Alegre, RS, Brazil
· KAPCZINSKI, Flavio:Univ Fed Rio Grande do Sul, HCPA, Bipolar Disorder Program PROTAHBI, Porto Alegre, RS, Brazil; Univ Fed Rio Grande do Sul, HCPA, Natl Sci & Technol Inst Translat Med INCT TM, Porto Alegre, RS, Brazil
hcfmusp.origem.id WOS:000322543200005
hcfmusp.origem.id 2-s2.0-84881020434
hcfmusp.origem.id SCIELO:S1516-44462013000200126
hcfmusp.publisher.city SAO PAULO
hcfmusp.publisher.country BRAZIL
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dc.description.index MEDLINE
hcfmusp.citation.scopus 26
hcfmusp.citation.wos 25
hcfmusp.affiliation.country Brasil


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