Prevalence and clinical correlates of alcohol use disorders among bipolar disorder patients: Results from the Brazilian Bipolar Research Network

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dc.contributor Sistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP
dc.contributor.author NERY, Fabiano G. FMUSP-HC
MIRANDA-SCIPPA, Angela
NERY-FERNANDES, Fabiana
KAPCZINSKI, Flavio
LAFER, Beny FMUSP-HC
dc.date.issued 2014
dc.identifier.citation COMPREHENSIVE PSYCHIATRY, v.55, n.5, p.1116-1121, 2014
dc.identifier.issn 0010-440X
dc.identifier.uri http://observatorio.fm.usp.br/handle/OPI/7671
dc.description.abstract Objectives: To investigate prevalence rates and clinical correlates of alcohol use disorders (AUD) among bipolar disorder (BD) patients in a large sample from the Brazilian Bipolar Research Network. Methods: Four hundred and eighty-three DSM-IV BD patients, divided according to the presence or absence of a lifetime AUD diagnosis (BD-AUD vs. BD-nonAUD), were included. Demographic and clinical characteristics of these two groups were compared. Logistic regression was performed to identify which characteristics were most strongly associated with a lifetime AUD diagnosis. Results: Nearly 23% presented a lifetime AUD diagnosis. BD-AUD patients were more likely to be male, to present rapid cycling, post-traumatic stress disorder (PTSD), anorexia, other substance use disorders (SUD), family history of SUD, any substance Misuse during the first mood episode, history of psychosis, suicide attempts, and younger age at onset of illness than BD-nonAUD patients. Logistic regression showed that the variables most strongly associated with a lifetime AUD diagnosis were SUD (non-alcohol), any substance misuse during the first mood episode, PTSD, male gender, suicide attempt, family history of SUD, and younger age at onset of BD. Conclusions: BD-AUD patients begin their mood disorder earlier and present more suicidal behaviors than BD-nonAUD patients. Personal and family history of SUD may be good predictors of comorbid AUD among BD patients. These variables are easily assessed in the clinical setting and may help to identify a particularly severe subgroup of BD patients.
dc.description.sponsorship · INCT-TM
· CNPq
· CAPES
· FAPESP
dc.language.iso eng
dc.publisher W B SAUNDERS CO-ELSEVIER INC
dc.relation.ispartof Comprehensive Psychiatry
dc.rights restrictedAccess
dc.subject.other national epidemiologic survey; psychiatric comorbidity; substance-abuse; drug-abuse; i disorder; axis-i; illness; dependence; cooccurrence; anxiety
dc.title Prevalence and clinical correlates of alcohol use disorders among bipolar disorder patients: Results from the Brazilian Bipolar Research Network
dc.type article
dc.rights.holder Copyright W B SAUNDERS CO-ELSEVIER INC
dc.description.group LIM/21
dc.identifier.doi 10.1016/j.comppsych.2014.02.006
dc.identifier.pmid 24746528
dc.type.category original article
dc.type.version publishedVersion
hcfmusp.author NERY, Fabiano G.:HC:LIM/21
hcfmusp.author LAFER, Beny:FM:MPS
hcfmusp.author.external · MIRANDA-SCIPPA, Angela:Univ Fed Bahia, Dept Neurosci & Mental Hlth, Mood & Anxiety Disorders Program CETHA, Salvador, BA, Brazil
· NERY-FERNANDES, Fabiana:Univ Fed Bahia, Dept Neurosci & Mental Hlth, Mood & Anxiety Disorders Program CETHA, Salvador, BA, Brazil
· KAPCZINSKI, Flavio:Univ Fed Rio Grande do Sul, Dept Psychiat, Bipolar Disorder Program PROTAHBI, Porto Alegre, RS, Brazil
hcfmusp.origem.id 2-s2.0-84902533422
hcfmusp.origem.id WOS:000337850300009
hcfmusp.publisher.city PHILADELPHIA
hcfmusp.publisher.country USA
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dc.description.index MEDLINE
dc.identifier.eissn 1532-8384
hcfmusp.citation.scopus 19
hcfmusp.citation.wos 19
hcfmusp.affiliation.country Brasil


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